Therapy with monoclonal antibodies. An in vivo model for the assessment of therapeutic potential.

Reshaping human antibodies for therapy

1988 • 1,555 citations

Reshaping Human Antibodies: Grafting an Antilysozyme Activity

1988 • 348 citations

Induction of classical transplantation tolerance in the adult.

1989 • 325 citations

Induction of tolerance by monoclonal antibody therapy

1986 • 307 citations

Localization of the binding site for the human high-affinity Fc receptor on IgG

1988 • 287 citations

IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells.

1982 • 285 citations

Induction of tolerance in peripheral T cells with monoclonal antibodies

1990 • 285 citations

Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.

1988 • 269 citations

The binding affinity of human IgG for its high affinity Fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region.

1991 • 261 citations

Monoclonal Antibodies Against Rat Immunoglobulin Kappa Chains

1982 • 257 citations

Monoclonal-Antibody Therapy in Systemic Vasculitis

1990 • 238 citations

The induction of skin graft tolerance in major histocompatibility complex‐mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti‐CD4 and anti‐CD8 antibodies

1990 • 157 citations

Therapeutic potential of rat monoclonal antibodies: isotype specificity of antibody-dependent cell-mediated cytotoxicity with human lymphocytes.

1985 • 147 citations

Importance of antibody isotype in monoclonal anti-idiotype therapy of a murine B cell lymphoma. A study of hybridoma class switch variants.

1986 • 129 citations

Structure and Function of Antibodies

2021 • 57 citations

Mechanisms of anti-CD4-mediated depletion and immunotherapy. A study using a set of chimeric anti-CD4 antibodies.

1990 • 47 citations

Removal of T cells from bone marrow for transplantation. Comparison of rat monoclonal anti-lymphocyte antibodies of different isotypes.

1983 • 44 citations

Complement activation by immunoglobulin does not depend solely on C1q binding

1990 • 31 citations

[52] The detection and characterization of antigen-specific monoclonal antibodies using anti-immunoglobulin isotype antibodies coupled to red blood cells

1986 • 11 citations