Pre-steady-state kinetics of the activation of rabbit skeletal muscle myosin light chain kinase by Ca2+/calmodulin.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Enzyme kinetics; behavior and analysis of rapid equilibrium and steady state enzyme systems

1994 • 3,007 citations

Solid Phase Peptide Synthesis

1976 • 1,798 citations

Enzyme Kinetics Behavior and analysis of rapid equilibrium and steady state enzyme systems

1975 • 1,447 citations

Physiology of the Gastrointestinal Tract

1988 • 732 citations

Structural similarities between the Ca2+-dependent regulatory proteins of 3':5'-cyclic nucleotide phosphodiesterase and actomyosin ATPase.

1976 • 517 citations

Conformational transition accompanying the binding of calcium(2+) ion to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase

1977 • 472 citations

Alteration of cross-bridge kinetics by myosin light chain phosphorylation in rabbit skeletal muscle: implications for regulation of actin-myosin interaction.

1990 • 269 citations

Test reactions for a stopped-flow apparatus

1978 • 247 citations

Different phosphorylated forms of myosin in contracting tracheal smooth muscle.

1986 • 187 citations

Cross-bridge kinetics, cooperativity, and negatively strained cross-bridges in vertebrate smooth muscle. A laser-flash photolysis study.

1988 • 140 citations

Interaction of calmodulin and a calmodulin-binding peptide from myosin light chain kinase: major spectral changes in both occur as the result of complex formation

1985 • 133 citations

Rabbit skeletal muscle myosin light chain kinase. The calmodulin binding domain as a potential active site-directed inhibitory domain.

1987 • 122 citations

Solid Phase Peptide Synthesis

1993 • 121 citations

Quantitation of energy coupling between Ca2+, calmodulin, skeletal muscle myosin light chain kinase, and kinase substrates.

1984 • 120 citations

Spinach calmodulin: isolation, characterization, and comparison with vertebrate calmodulins

1980 • 118 citations

Changes in the structure of calmodulin induced by a peptide based on the calmodulin-binding domain of myosin light chain kinase

1989 • 118 citations

Relationship between force and Ca2+ concentration in smooth muscle as revealed by measurements on single cells.

1988 • 115 citations

Discrete Numerical Methods in Physics and Engineering

1974 • 112 citations

4 Calmodulin-Dependent Protein Kinases

1986 • 111 citations

Determination of the free-energy coupling for binding of calcium ion and troponin I to calmodulin

1982 • 110 citations

Restoration of the calcium binding activity of mutant calmodulins toward normal by the presence of a calmodulin binding structure

1991 • 103 citations

Activation of Smooth Muscle Contraction: Relation Between Myosin Phosphorylation and Stiffness

1986 • 102 citations

A Symposium on the Mechanism of Enzyme Action

1954 • 95 citations

Pseudosubstrates turn off protein kinases

1988 • 81 citations

Calmodulin and intracellular Ca2+ receptors

1983 • 58 citations

Shape and substructure of skeletal muscle myosin light chain kinase

1983 • 52 citations

Domain characterization of rabbit skeletal muscle myosin light chain kinase.

1990 • 52 citations

Myosin light chain kinases and myosin phosphorylation in skeletal muscle

1985 • 50 citations

Phosphorylation of synthetic peptides by skeletal muscle myosin light chain kinases.

1986 • 48 citations

Ammonium 4-chloro-7-sulfobenzofurazan: A new fluorigenic thiol-specific reagent

1982 • 46 citations

Fluorescence studies of the interaction of calmodulin with myosin light chain kinase.

1981 • 46 citations

Biologically active fluorescent derivatives of spinach calmodulin that report calmodulin target protein binding

1988 • 46 citations

Characterization of chicken skeletal muscle myosin light chain kinase. Evidence for muscle-specific isozymes.

1985 • 44 citations

Amino Acid Sequence of Calmodulin from Wheat Germ

1985 • 44 citations

Structural characterization of the interactions between calmodulin and skeletal muscle myosin light chain kinase: effect of peptide (576-594)G binding on the calcium-binding domains

1989 • 44 citations

A continuous fluorescence assay for protein kinase C

1991 • 31 citations

Calcium release from calmodulin and its C‐terminal or N‐terminal halves in the presence of the calmodulin antagonists phenoxybenzamine and melittin measured by stopped‐flow fluorescence with Quin 2 and intrinsic tyrosine

1986 • 27 citations

[8] Spectroscopic analyses of calmodulin and its interactions

1983 • 22 citations

Fluorometric assay for adenosine 3',5'-cyclic monophosphate-dependent protein kinase and phosphoprotein phosphatase activities.

1981 • 20 citations

[2] Purification of plant calmodulin

1983 • 14 citations

Fluorescent adducts of wheat calmodulin implicate the amino-terminal region in the activation of skeletal muscle myosin light chain kinase.

1990 • 13 citations

Activation mechanism of rabbit skeletal muscle myosin light chain kinase 5′‐p‐Fluorosulfonylbenzoyl adenosine as a probe of the MgATP‐binding site of the calmodulin‐bound and calmodulin‐free enzyme

1991 • 9 citations

Ligand‐triggered conformational perturbations elicit changes at the single cysteinyl residue of spinach calmodulin

1988 • 6 citations