Novel Injury Mechanism in Anoxia and Trauma of Spinal Cord White Matter: Glutamate Release via Reverse Na⁺-dependent Glutamate Transport

Glutamate: A Neurotransmitter in Mammalian Brain

1984 • 1,981 citations

Localization of neuronal and glial glutamate transporters

1994 • 1,668 citations

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1994 • 988 citations

Nonvesicular release of neurotransmitter

1993 • 837 citations

Flux coupling in a neuronal glutamate transporter

1996 • 835 citations

Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger

1992 • 656 citations

A Mechanistic Analysis of Nondisruptive Axonal Injury: A Review

1997 • 571 citations

Glutamate Transporter Protein Subtypes Are Expressed Differentially during Rat CNS Development

1997 • 553 citations

Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity

1998 • 538 citations

Stoichiometry of the Glial Glutamate Transporter GLT-1 Expressed Inducibly in a Chinese Hamster Ovary Cell Line Selected for Low Endogenous Na⁺-Dependent Glutamate Uptake

1998 • 454 citations

Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons

1995 • 366 citations

Vascular mechanisms in the pathophysiology of human spinal cord injury

1997 • 353 citations

Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes

1997 • 352 citations

Mechanisms of secondary injury to spinal cord axons in vitro: role of Na+, Na(+)-K(+)-ATPase, the Na(+)-H+ exchanger, and the Na(+)-Ca2+ exchanger

1996 • 275 citations

Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX

1994 • 238 citations

Role of NMDA and Non-NMDA Ionotropic Glutamate Receptors in Traumatic Spinal Cord Axonal Injury

1997 • 227 citations

Cellular and Subcellular Distribution of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and Its mRNA in the Rat Central Nervous System

1988 • 210 citations

Calcium signaling of glial cells along mammalian axons

1993 • 204 citations

Expression of the glutamate transporter GLT1 in neural cells of the rat central nervous system: Non-radioactive in situ hybridization and comparative immunocytochemistry

1996 • 150 citations

Neuronal Expression of the Glutamate Transporter GLT-1 in Hippocampal Microcultures

1998 • 141 citations

Local Blockade of Sodium Channels by Tetrodotoxin Ameliorates Tissue Loss and Long-Term Functional Deficits Resulting from Experimental Spinal Cord Injury

1997 • 139 citations

Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS

1996 • 131 citations

2,3-Dihydroxy-6-Nitro-7-Sulfamoyl-Benzo(f)Quinoxaline Reduces Glial Loss and Acute White Matter Pathology after Experimental Spinal Cord Contusion

1999 • 122 citations

Mechanisms of calcium and sodium fluxes in anoxic myelinated central nervous system axons

1997 • 113 citations

Mechanism of glutamate release from rat hippocampal slices during in vitro ischemia

1996 • 111 citations

Effects of Glucose Deprivation, Chemical Hypoxia, and Simulated Ischemia on Na⁺Homeostasis in Rat Spinal Cord Astrocytes

1998 • 111 citations

Delayed Antagonism of AMPA/Kainate Receptors Reduces Long-Term Functional Deficits Resulting from Spinal Cord Trauma

1997 • 108 citations

Pharmacological characterization of swelling-induced<scp>d</scp>-[³H]aspartate release from primary astrocyte cultures

1998 • 106 citations

Differences in degree of trapping of low-affinity uncompetitive N-methyl-D-aspartic acid receptor antagonists with similar kinetics of block.

1999 • 92 citations

L-TRANs-Pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1, 3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters

1994 • 85 citations

Elemental composition and water content of rat optic nerve myelinated axons and glial cells: effects of in vitro anoxia and reoxygenation

1995 • 77 citations

Anoxia-Induced Changes in Extracellular K⁺and pH in Mammalian Central White Matter

1992 • 71 citations

Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.

1997 • 70 citations

Anoxie Injury in the Rat Spinal Cord: Pharmacological Evidence for Multiple Steps in Ca²⁺-Dependent Injury of the Dorsal Columns

1997 • 66 citations

Anoxic injury of CNS white matter

1990 • 66 citations

Ion Transport and Membrane Potential in CNS Myelinated Axons II. Effects of Metabolic Inhibition

1997 • 49 citations

Vascular mechanisms in the pathophysiology of human spinal cord injury

1997 • 24 citations

Expression of high-affinity neuronal and glial glutamate transporters in the rat optic nerve

1997 • 24 citations

Overview of Spinal Cord Injury

1992 • 17 citations

Diffuse axonal injury

1995 • 16 citations

Expression of high‐affinity neuronal and glial glutamate transporters in the rat optic nerve

1997 • 1 citations