Intracellular glutathione levels regulate Fos/Jun induction and activation of glutathione S-transferase gene expression.

[1] Role of free radicals and catalytic metal ions in human disease: An overview

1990 • 5,041 citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Oxidative stress: From basic research to clinical application

1991 • 1,302 citations

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

1991 • 906 citations

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1992 • 874 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants.

1990 • 522 citations

Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver.

1988 • 408 citations

Glutathione S-Transferases: Gene Structure and Regulation of Expression

1993 • 300 citations

Transcriptional activation of early‐response genes by hydrogen peroxide in a mouse osteoblastic cell line

1991 • 298 citations

[8] Chemical depletion of glutathione in vivo

1981 • 242 citations

Two adjacent AP-1-like binding sites form the electrophile-responsive element of the murine glutathione S-transferase Ya subunit gene.

1992 • 230 citations

Lest I Forget Thee, Glutathione …

1969 • 190 citations

Induction of cystine and glutamate transport activity in human fibroblasts by diethyl maleate and other electrophilic agents.

1984 • 140 citations

Induction of AP-1 (Fos/Jun) by chemical agents mediates activation of glutathione S-transferase and quinone reductase gene expression.

1994 • 97 citations

Phenobarbital induction of AP-1 binding activity mediates activation of glutathione S-transferase and quinone reductase gene expression

1993 • 74 citations

Molecular Mechanisms in Protection Against Carcinogenesis

1987 • 53 citations

EPR method for the measurement of cellular sulfhydryl groups

1991 • 35 citations