Endogenous epoxyeicosatrienoyl-phospholipids. A novel class of cellular glycerolipids containing epoxidized arachidonate moieties.

ARACHIDONIC ACID METABOLISM

1986 • 1,802 citations

Mechanisms and Consequences of Lipid Peroxidation in Biological Systems

1985 • 520 citations

A new role for phospholipase A2: protection of membranes from lipid peroxidation damage

1987 • 428 citations

PHOSPHOLIPID BIOSYNTHESIS IN YEAST

1989 • 326 citations

Metabolism of arachidonic acid in ionophore-stimulated neutrophils. Esterification of a hydroxylated metabolite into phospholipids.

1979 • 297 citations

Cytochrome P-450 metabolism of arachidonic acid: formation and biological actions of "epoxygenase"-derived eicosanoids.

1988 • 261 citations

Oxygenation of biological membranes by the pure reticulocyte lipoxygenase.

1990 • 244 citations

Regulation of the biosynthesis of triacylglycerol, phosphatidylcholine and phosphatidylethanolamine in the liver

1989 • 228 citations

Reduced Triphosphopyridine Nucleotide Oxidase-catalyzed Alterations of Membrane Phospholipids

1971 • 223 citations

A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria

1975 • 202 citations

Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension.

1990 • 169 citations

Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: agonist-induced deacylation and transformation of stored hydroxyeicosanoids.

1990 • 164 citations

Acylation of lysophospholipids by rabbit alveolar macrophages. Specificities of CoA-dependent and CoA-independent reactions.

1985 • 156 citations

Lipid peroxidation and phospholipase A2 activity in liposomes composed of unsaturated phospholipids: a structural basis for enzyme activation

1988 • 154 citations

Analysis of a specific oxygenation reaction of soybean lipoxygenase-1 with fatty acids esterified in phospholipids

1987 • 152 citations

Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal arachidonic acid epoxygenase.

1990 • 143 citations

The maturational breakdown of mitochondria in reticulocytes

1986 • 137 citations

Identification, isolation and characterization of epidermal lipids containing linoleic acid

1985 • 131 citations

Prostaglandins and Membrane Ion Transport

1984 • 130 citations

Arachidonoyl-CoA synthetase. Separation from nonspecific acyl-CoA synthetase and distribution in various cells and tissues.

1985 • 105 citations

Occurrence of lipoxygenase products in membranes of rabbit reticulocytes. Evidence for a role of the reticulocyte lipoxygenase in the maturation of red cells.

1990 • 100 citations

Epoxyeicosatrienoic acids activate Na⁺/H⁺ exchange and are mitogenic in cultured rat glomerular mesangial cells

1990 • 97 citations

Cytochrome P-450-dependent oxidation of arachidonic acid to 16-, 17-, and 18-hydroxyeicosatetraenoic acids.

1990 • 96 citations

Endogenous epoxyeicosatrienoic acids

1989 • 96 citations

Esterification of an endogenously synthesized lipoxygenase product into granulocyte cellular lipids

1981 • 93 citations

[43] Cytochrome P-450 arachidonate oxygenase

1990 • 92 citations

COA-independent transfer of arachidonic acid from 1,2-diacyl-sn-glycero-3-phosphocholine to 1-0-alkyl-sn-glycero-3-phosphocholine (lyso plateletactivating factor) by macrophage microsomes

1985 • 85 citations

Arachidonic acid epoxygenase

1990 • 70 citations

Epoxygenase Products of Arachidonic Acid Are Endogenous Constituents of the Hypothalamus Involved in D₂Receptor-Mediated, Dopamine-Induced Release of Somatostatin

1990 • 60 citations

5,6-epoxyeicosatrienoic acid mobilizes Ca2+ in anterior pituitary cells

1986 • 59 citations

Arachidonate epoxygenase: identification of epoxyeicosatrienoic acids in rabbit kidney.

1987 • 57 citations

Free and esterified 13(R,S)-hydroxyoctadecadienoic acids: principal oxygenase products in psoriatic skin scales.

1990 • 56 citations

Resolution of epoxyeicosatrienoate enantiomers by chiral phase chromatography

1989 • 54 citations

Quantitative and mechanistic aspects of the hydroperoxide‐induced release of Ca²⁺ from rat liver mitochondria

1985 • 52 citations

Incorporation of arachidonic acid into 1-acyl-2-lyso-sn-glycero-3-phosphocholine of the human neutrophil

1987 • 50 citations

Preferential hydrolysis of peroxidized phospholipid by lysosomal phospholipase C

1988 • 47 citations

A novel pool of rat liver inositol and ethanolamine phospholipids contains epoxyeicosatrienoic acids (EETs)

1987 • 43 citations

Auto-oxidation-induced fusion of lipid vesicles

1982 • 43 citations

Studies on the conformational mobility of arachidonic acid. Facile macrolactonization of 20-hydroxyarachidonic acid.

1983 • 34 citations

Occurrence of 9- and 13-keto-octadecadienoic acid in biological membranes oxygenated by the reticulocyte lipoxygenase

1990 • 26 citations

[5] Separation of S-acyl-CoA thioesters and related compounds by reversed-phase ion-pair chromatography

1981 • 22 citations

Incorporation of hydroxyeicosatetraenoic acids into cellular lipips of adrenal glomerulosa cells: Inhibition of aldosterone release by 5-HETE

1989 • 18 citations

Formation of cis-14,15-oxido-5,8,11-icosatrienoic acid from phosphatidylinositol in human platelets.

1987 • 17 citations

Tris(tetraphenylimidodiphosphinato)praseodymium: a powerful tool for the analysis of fatty acids by 1H n.m.r. spectroscopy

1988 • 14 citations

[39] Long-chain acyl-CoA synthetases I and II from Candida lipolytica

1981 • 12 citations

Does arachidonic acid exist in a well defined tertiary structure ?

1989 • 4 citations