Copper-induced trafficking of the cU-ATPases: a key mechanism for copper homeostasis.

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

1993 • 1,905 citations

Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper–transporting ATPase

1993 • 1,395 citations

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

1993 • 1,345 citations

Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein

1993 • 720 citations

A Delicate Balance: Homeostatic Control of Copper Uptake and Distribution

1999 • 715 citations

Isolation of a partial candidate gene for Menkes disease by positional cloning

1993 • 690 citations

The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake

1994 • 659 citations

Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking.

1996 • 623 citations

A family of yeast expression vectors containing the phage f1 intergenic region1

1987 • 514 citations

Isolation and Characterization of a Human Liver cDNA as a Candidate Gene for Wilson Disease

1993 • 501 citations

Biochemistry of Copper

1991 • 473 citations

The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake.

1995 • 431 citations

Biochemical Characterization of the Wilson Disease Protein and Functional Expression in the Yeast Saccharomyces cerevisiae

1997 • 324 citations

Cellular Copper Transport and Metabolism

2000 • 308 citations

Cellular Copper Transport

1995 • 281 citations

Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion

2000 • 260 citations

Menkes' Kinky Hair Disease: Further Definition of the Defect in Copper Transport

1973 • 217 citations

Disorders of copper transport

1995 • 195 citations

Gene amplification of the Menkes (MNK; ATP7A) P-type ATPase gene of CHO cells is associated with copper resistance and enhanced copper efflux

1995 • 178 citations

Characterization of the Interaction between the Wilson and Menkes Disease Proteins and the Cytoplasmic Copper Chaperone, HAH1p

1999 • 168 citations

The Role of GMXCXXC Metal Binding Sites in the Copper-induced Redistribution of the Menkes Protein

1999 • 167 citations

Copper-dependent trafficking of Wilson disease mutant ATP7B proteins

2000 • 167 citations

Functional Characterization of Missense Mutations in ATP7B: Wilson Disease Mutation or Normal Variant?

1998 • 166 citations

Sequence, mapping and disruption of CCC2, a gene that cross‐complements the Ca²⁺‐sensitive phenotype of csg1 mutants and encodes a P‐type ATPase belonging to the Cu²⁺‐ATPase subfamily

1995 • 166 citations

Role of the Copper-binding Domain in the Copper Transport Function of ATP7B, the P-type ATPase Defective in Wilson Disease

1999 • 163 citations

Functional Expression of the Menkes Disease Protein Reveals Common Biochemical Mechanisms Among the Copper-transporting P-type ATPases

1998 • 158 citations

Copper absorption, excretion, and retention by young men consuming low dietary copper determined by using the stable isotope 65Cu

1998 • 134 citations

Effect of the toxic milk mutation (tx) on the function and intracellular localization of Wnd, the murine homologue of the Wilson copper ATPase

2001 • 96 citations

Functional analysis and intracellular localization of the human menkes protein (MNK) stably expressed from a cDNA construct in Chinese hamster ovary cells (CHO-K1)

1998 • 89 citations

Characterization of the Menkes Protein Copper-Binding Domains and Their Role in Copper-Induced Protein Relocalization

1999 • 77 citations

Defective Copper-Induced Trafficking and Localization of the Menkes Protein in Patients With Mild and Copper-Treated Classical Menkes Disease

1999 • 68 citations

Intracellular localization and loss of copper responsiveness of Mnk, the murine homologue of the Menkes protein, in cells from blotchy (Mo blo) and brindled (Mo br) mouse mutants

1999 • 60 citations

Structure of the P-type ATPases

1998 • 51 citations

Copper Transport in Mammals

1999 • 48 citations

On the Mechanism of ATP‐Driven Ca²⁺ Transport by the Calcium ATPase of Sarcoplasmic Reticulum

1992 • 19 citations