The cyclophilin component of the unactivated estrogen receptor contains a tetratricopeptide repeat domain and shares identity with p59 (FKBP59)

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Basic local alignment search tool

1990 • 87,358 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

1990 • 507 citations

Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein.

1985 • 492 citations

Common non-hormone binding component in non-transformed chick oviduct receptors of four steroid hormones

1984 • 442 citations

Evidence That the 90-kDa Heat Shock Protein Is Necessary for the Steroid Binding Conformation of the L Cell Glucocorticoid Receptor

1989 • 394 citations

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence.

1991 • 319 citations

Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

1992 • 307 citations

Snap helix with knob and hole: Essential repeats in S. pombe nuclear protein nuc2 +

1990 • 306 citations

A 90,000-dalton binding protein common to both steroid receptors and the Rous sarcoma virus transforming protein, pp60v-src.

1985 • 304 citations

Isolation and amino acid sequence of cyclophilin.

1986 • 294 citations

The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein

1989 • 288 citations

A region in the steroid binding domain determines formation of the non-DNA-binding, 9 S glucocorticoid receptor complex.

1988 • 267 citations

A 59-kilodalton protein associated with progestin, estrogen, androgen, and glucocorticoid receptors

1986 • 261 citations

Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes.

1992 • 252 citations

Isolation and characterization of STI1, a stress-inducible gene from Saccharomyces cerevisiae.

1989 • 248 citations

Purification of unactivated progesterone receptor and identification of novel receptor-associated proteins.

1990 • 229 citations

Hsp56: a novel heat shock protein associated with untransformed steroid receptor complexes.

1990 • 221 citations

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

1988 • 220 citations

The 56-59-kilodalton protein identified in untransformed steroid receptor complexes is a unique protein that exists in cytosol in a complex with both the 70- and 90-kilodalton heat shock proteins

1990 • 210 citations

Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.

1990 • 201 citations

Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae.

1987 • 192 citations

Binding of heat shock proteins to the avian progesterone receptor.

1989 • 192 citations

Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes

1990 • 189 citations

Immunological evidence that the nonhormone binding component of avian steroid receptors exists in a wide range of tissues and species

1985 • 188 citations

Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90

1990 • 187 citations

P59, an hsp 90-binding protein. Cloning and sequencing of its cDNA and preparation of a peptide-directed polyclonal antibody.

1992 • 181 citations

Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events.

1992 • 178 citations

Evidence that the 90-kDa heat shock protein (HSP90) exists in cytosol in heteromeric complexes containing HSP70 and three other proteins with Mr of 63,000, 56,000, and 50,000.

1991 • 177 citations

The non-DNA-binding heterooligomeric form of mammalian steroid hormone receptors contains a hsp90-bound 59-kilodalton protein.

1990 • 174 citations

The Hsp56 component of steroid receptor complexes binds to immobilized FK506 and shows homology to FKBP-12 and FKBP-13.

1992 • 170 citations

Molecular cloning and expression of a transformation-sensitive human protein containing the TPR motif and sharing identity to the stress-inducible yeast protein STI1.

1992 • 160 citations

A novel secreted cyclophilin-like protein (SCYLP)

1991 • 138 citations

Isolation and characterization of a 40-kDa cyclophilin-related protein.

1992 • 125 citations

Import of proteins into mitochondria: nucleotide sequence of the gene for a 70-kd protein of the yeast mitochondrial outer membrane.

1983 • 110 citations

Isolation of a feline leukaemia provirus containing the oncogene myc from a feline lymphosarcoma

1984 • 109 citations

Protein components of the nonactivated glucocorticoid receptor.

1991 • 83 citations

The murine plasma cell antigen PC-1: purification and partial amino acid sequence.

1985 • 66 citations

Structure and nuclear localization signal of the SK13 antiviral protein of Saccharomyces cerevisiae

1989 • 66 citations

Isolation of untransformed bovine estrogen receptor without molybdate stabilization

1990 • 41 citations

Purification of the molybdate-stabilized 9-10 S estradiol receptor from calf uterus.

1985 • 27 citations

The Interaction Site for Tamoxifen Aziridine with the Bovine Estrogen Receptor

1989 • 10 citations