Platelet membrane glycoprotein IIb heavy chain forms a complex with glycoprotein IIIa that binds Arg-Gly-Asp peptides

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

The platelet membrane glycoprotein IIb-IIIa complex

1988 • 1,031 citations

Platelet Membrane Glycoprotein IIb/IIIa: Member of a Family of Arg-Gly-Asp—Specific Adhesion Receptors

1986 • 945 citations

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

1979 • 868 citations

Human platelets possess an inducible and saturable receptor specific for fibrinogen.

1979 • 713 citations

The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets.

1985 • 594 citations

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.

1985 • 517 citations

Amino acid sequence of human von Willebrand factor

1986 • 486 citations

Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to “integrin”.

1987 • 466 citations

Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis.

1977 • 451 citations

Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors.

1987 • 428 citations

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.

1983 • 315 citations

Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets.

1981 • 300 citations

Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin

1985 • 299 citations

Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion.

1988 • 280 citations

Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.

1982 • 261 citations

Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human platelets

1985 • 253 citations

Evidence that arginyl-glycyl-aspartate peptides and fibrinogen gamma chain peptides share a common binding site on platelets.

1987 • 222 citations

Inhibition of fibronectin binding to platelets by proteolytic fragments and synthetic peptides which support fibroblast adhesion.

1985 • 220 citations

Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets.

1982 • 190 citations

Comparison of cDNA-derived protein sequences of the human fibronectin and vitronectin receptor .alpha.-subunits and platelet glycoprotein IIb

1987 • 183 citations

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3

1985 • 175 citations

Reduced surface expression and binding of fibronectin by thrombin-stimulated thrombasthenic platelets.

1983 • 168 citations

Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins

1987 • 168 citations

Arginyl-glycyl-aspartic acid sequences and fibrinogen binding to platelets

1987 • 165 citations

Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia.

1986 • 161 citations

Platelet glycoproteins IIb and IIIa: evidence for a family of immunologically and structurally related glycoproteins in mammalian cells.

1986 • 157 citations

Immunologic relationship between platelet membrane glycoprotein GPIIb/IIIa and cell surface molecules expressed by a variety of cells.

1986 • 152 citations

Platelet-collagen adhesion: inhibition by a monoclonal antibody that binds glycoprotein IIb.

1984 • 148 citations

Comparison of fibrinogen association with normal and thrombasthenic platelets on exposure to ADP or chymotrypsin

1979 • 138 citations

Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa.

1987 • 133 citations

Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits.

1987 • 131 citations

Chemical cross-linking of arginyl-glycyl-aspartic acid peptides to an adhesion receptor on platelets.

1988 • 119 citations

The mechanism of thrombin-induced platelet factor 4 secretion

1980 • 104 citations

ADP-dependent common receptor mechanism for binding of von Willebrand factor and fibrinogen to human platelets.

1984 • 79 citations

Alternative proteolytic processing of platelet membrane glycoprotein IIb.

1988 • 54 citations

Platelet membrane proteins.

1985 • 27 citations