Adenosine deaminase impairment and ribonucleotide reductase activity and levels in HeLa cells.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

ADENOSINE-DEAMINASE DEFICIENCY IN TWO PATIENTS WITH SEVERELY IMPAIRED CELLULAR IMMUNITY

1972 • 1,654 citations

NUCLEOSIDE-PHOSPHORYLASE DEFICIENCY IN A CHILD WITH SEVERELY DEFECTIVE T-CELL IMMUNITY AND NORMAL B-CELL IMMUNITY

1975 • 855 citations

RAPID, SIMULTANEOUS MEASUREMENT OF DNA, PROTEIN, AND CELL VOLUME IN SINGLE CELLS FROM LARGE MAMMALIAN CELL POPULATIONS

1973 • 560 citations

The Role of Adenosine and 2'-Deoxyadenosine in Mammalian Cells

1978 • 518 citations

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

1977 • 416 citations

Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency.

1978 • 399 citations

Regulation of Mammalian Deoxyribonucleotide Biosynthesis by Nucleotides as Activators and Inhibitors

1966 • 395 citations

Ribonucleotide Reductase and Cell Proliferation

1970 • 307 citations

Identification and quantitation of adenine deoxynucleotides in erythrocytes of a patient with adenosine deaminase deficiency and severe combined immunodeficiency.

1978 • 277 citations

Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

1978 • 230 citations

Deoxyguanosine Triphosphate as a Possible Toxic Metabolite in the Immunodeficiency Associated with Purine Nucleoside Phosphorylase Deficiency

1978 • 215 citations

Purinogenic immunodeficiency diseases: selective toxicity of deoxyribonucleosides for T cells.

1978 • 209 citations

A method for the determination of dATP and dTTP in picomole amounts

1970 • 206 citations

Overproduction of adenine deoxynucleosides and deoxynucletides in adenosine deaminase deficiency with severe combined immunodeficiency disease.

1978 • 200 citations

Differential Sensitivity of Human Leukemic T Cell Lines and B Cell Lines to Growth Inhibition by Deoxyadenosine

1978 • 167 citations

Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease

1979 • 158 citations

Cell-cycle-dependent variations of deoxyribonucleoside triphosphate pools in chinese hamster cells

1973 • 156 citations

Formation of Deoxycytidine Phosphates from Cytidine Phosphates in Extracts from Escherichia coli

1961 • 142 citations

The Ability of Purine and Thymine Derivatives and of Glycine to Support the Growth of Mammalian Cells in Culture

1959 • 136 citations

Deoxyribonucleoside‐Triphosphate Pools and DNA Synthesis in Synchronized Hamster Cells

1973 • 136 citations

ADENOSINE-DEAMINASE DEFICIENCY AND COMBINED IMMUNODEFICIENCY SYNDROME

1972 • 133 citations

Levels of Ribonucleotide Reductase Activity during the Division Cycle of the L Cell

1968 • 103 citations

CELL‐CYCLE ANALYSIS OF PERTURBED CELL POPULATIONS: COMPUTER SIMULATION OF SEQUENTIAL DNA DISTRIBUTIONS

1976 • 90 citations

On the effect of some adenine derivatives on the incorporation in vitro of isotopically labelled compounds into the nucleic acids of ehrlich ascites tumor cells

1959 • 81 citations

Synchronized mammalian cell cultures

1969 • 71 citations

Rates of DNA synthesis during the S-phase of HeLa cells.

1978 • 62 citations

The effect of external deoxyribonucleosides on deoxyribonucleoside triphosphate concentrations in human lymphocytes

1975 • 58 citations

Ribonucleic Acid Biosynthesis of Human Cells during Amino Acid Deprivation

1969 • 54 citations

Formation in vitro of deoxyadenosine triphosphate from deoxyadenosine in Ehrlich ascites cells

1960 • 54 citations

Functional Regulation of Mammalian Ribonucleotide Reductase

1972 • 54 citations

Adenosine metabolism in cultured lymphoid cells

1977 • 39 citations

Toxicities of adenosine and 2'-deoxyadenosine in l cells treated with inhibitors of adenosine deaminase

1977 • 38 citations

Effect of methotrexate and 5-fluorodeoxyuridine on ribonucleotide reductase activity in mammalian cells.

1977 • 38 citations