Primary structure of the lactose permease gene from the yeast Kluyveromyces lactis. Presence of an unusual transcript structure.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Experiments in molecular genetics

1972 • 28,260 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

Analysis of membrane and surface protein sequences with the hydrophobic moment plot

1984 • 2,234 citations

Rapid similarity searches of nucleic acid and protein data banks.

1983 • 1,577 citations

Sequence and Structure of a Human Glucose Transporter

1985 • 1,557 citations

Hybridization of nucleic acids immobilized on solid supports

1984 • 1,357 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

1982 • 801 citations

The pIC plasmid and phage vectors with versatile cloning sites for recombinant selection by insertional inactivation

1984 • 718 citations

Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast.

1985 • 526 citations

Sequence of the lactose permease gene

1980 • 501 citations

Bifunctional messenger RNAs in eukaryotes

1986 • 405 citations

Mammalian and bacterial sugar transport proteins are homologous

1987 • 400 citations

Specific labeling and partial purification of the M protein, a component of the beta-galactoside transport system of Escherichia coli.

1965 • 374 citations

Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae.

1985 • 342 citations

Point mutations identify the conserved, intron-contained TACTAAC box as an essential splicing signal sequence in yeast

1984 • 339 citations

Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium

1982 • 322 citations

Nucleotide sequence of a yeast Ty element: evidence for an unusual mechanism of gene expression.

1985 • 321 citations

Nucleosomes will not form on double-stranded RNA or over poly(dA)-poly(dT) tracts in recombinant DNA

1981 • 244 citations

Nucleotide sequence of The yeastSUC2gene for invertase

1983 • 225 citations

Structure-independent nucleotide sequence analysis.

1979 • 199 citations

Nucleotide sequence of the melB gene and characteristics of deduced amino acid sequence of the melibiose carrier in Escherichia coli.

1984 • 171 citations

Molecular characterization of the CAN1 locus in Saccharomyces cerevisiae. A transmembrane protein without N-terminal hydrophobic signal sequence.

1985 • 161 citations

Analysis of theKluyveromyces lactispositive regulatory geneLAC9reveals functional homology to, but sequence divergence from, theSaccharomyces cerevisiae GALAgene

1986 • 158 citations

The histidine permease gene (HIP1) of Saccharomyces cerevisiae

1985 • 154 citations

Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein.

1988 • 139 citations

Nucleosome reconstitution on plasmid-inserted poly(dA) . poly(dT).

1982 • 139 citations

Lac permease of Escherichia: histidine-322 and glutamic acid-325 may be components of a charge-relay system

1986 • 137 citations

Structural and functional role of leucine residues in proteins

1973 • 135 citations

Characterization of a Positive Regulatory Gene, LAC9, That Controls Induction of the Lactose-Galactose Regulon of Kluyveromyces lactis: Structural and Functional Relationships to GAL4 of Saccharomyces cerevisiae

1987 • 128 citations

Nucleotide sequence of Saccharomyces cerevisiae genes TRP2 and TRP3 encoding bifunctional anthranilate synthase: indole-3-glycerol phosphate synthase.

1984 • 127 citations

GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae

1986 • 127 citations

Construction of strains of Saccharomyces cerevisiae that grow on lactose.

1985 • 117 citations

MOLECULAR ASPECTS OF SUGAR:ION COTRANSPORT

1986 • 108 citations

Use of site-directed mutagenesis to study the mechanism of a membrane transport protein

1987 • 87 citations

Lac permease of Escherichia coli: arginine-302 as a component of the postulated proton relay

1987 • 86 citations

Lac permease of Escherichia coli: histidine-205 and histidine-322 play different roles in lactose/protein symport

1986 • 84 citations

Characterization of lactose transport in Kluyveromyces lactis

1983 • 81 citations

Rapid sequence determination of late simian virus 40 16S mRNA leader by using inhibitors of reverse transcriptase.

1979 • 78 citations

Site-specific mutagenesis of histidine residues in the lac permease of Escherichia coli.

1985 • 74 citations

One-step gene replacement in yeast by cotransformation

1985 • 70 citations

Nucleotide sequence of Klebsiella pneumoniae lac genes

1985 • 64 citations

cys154 Is important for lac permease activity in Escherichia coli

1985 • 62 citations

The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport.

1985 • 60 citations

Role of cysteine residues in the lac permease of Escherichia coli

1987 • 58 citations

Genetic and biochemical characterization of the galactose gene cluster in Kluyveromyces lactis

1984 • 48 citations

LAC4 IS THE STRUCTURAL GENE FOR β-GALACTOSIDASE IN KLUYVEROMYCES LACTIS

1981 • 46 citations

Structure and function of the yeast tRNA ligase gene.

1988 • 43 citations

Defective plasma membrane assembly in yeast secretory mutants

1984 • 43 citations

Positive regulation of the beta-galactosidase gene from Kluyveromyces lactis is mediated by an upstream activation site that shows homology to the GAL upstream activation site of Saccharomyces cerevisiae.

1987 • 40 citations

Isolation and characterization of mutants of Kluyveromyces lactis defective in lactose transport

1987 • 40 citations

Identification of Upstream Activator Sequences That Regulate Induction of the β-Galactosidase Gene in Kluyveromyces lactis

1987 • 34 citations

Site-specific alteration of cysteine 176 and cysteine 234 in the lactose carrier of Escherichia coli.

1986 • 32 citations

Lactose permease of Escherichia coli: properties of mutants defective in substrate translocation.

1987 • 30 citations

The amino acid sequence of the histidine binding protein of Salmonella typhimurium.

1981 • 21 citations