Structure and expression of the rat apolipoprotein E gene.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

Cytoplasmic dot hybridization. Simple analysis of relative mRNA levels in multiple small cell or tissue samples.

1982 • 1,333 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Lipoprotein receptors and cholesterol homeostasis

1983 • 755 citations

Human apolipoprotein E. The complete amino acid sequence.

1982 • 731 citations

Repetitive Sequences in Eukaryotic DNA and their Expression

1982 • 575 citations

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

1981 • 568 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.

1985 • 500 citations

Disturbances in Lipid and Lipoprotein Metabolism

1978 • 482 citations

Sequence of introns and flanking exons in wild-type and box3 mutants of cytochrome b reveals an interlaced splicing protein coded by an intron

1980 • 477 citations

Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

1984 • 435 citations

Lipoprotein apoprotein metabolism.

1978 • 390 citations

Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene.

1985 • 352 citations

Structural basis for receptor binding heterogeneity of apolipoprotein E from type III hyperlipoproteinemic subjects.

1982 • 349 citations

Structural and functional analysis of the human metallothionein-IA gene: Differential induction by metal ions and glucocorticoids

1984 • 331 citations

Adenosine deaminase: characterization and expression of a gene with a remarkable promoter.

1985 • 329 citations

Biochemical and genetic studies of the apoprotein E secreted by mouse macrophages and human monocytes.

1982 • 296 citations

Nucleotide sequence and structure of the human apolipoprotein E gene.

1985 • 289 citations

DNA Sequences Mediating Class Switching in α-Immunoglobulins

1980 • 243 citations

Apolipoprotein E synthesis in human kidney, adrenal gland, and liver.

1983 • 224 citations

Expression of Plasmodium falciparum blood-stage antigens in Escherichia coli: detection with antibodies from immune humans.

1983 • 211 citations

Switch region of immunoglobulin Cμ gene is composed of simple tandem repetitive sequences

1981 • 173 citations

Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement.

1985 • 160 citations

Human apolipoprotein E mRNA. cDNA cloning and nucleotide sequencing of a new variant.

1984 • 151 citations

Rat apolipoprotein E mRNA. Cloning and sequencing of double-stranded cDNA.

1983 • 137 citations

Gene encoding parathyroid hormone. Nucleotide sequence of the rat gene and deduced amino acid sequence of rat preproparathyroid hormone.

1984 • 120 citations

A novel electrophoretic variant of human apolipoprotein E. Identification and characterization of apolipoprotein E1.

1984 • 112 citations

Isolation of the bacteriophage lambda A-gene protein.

1975 • 102 citations

Endotoxin suppresses expression of apoprotein E by mouse macrophages in vivo and in culture. A biochemical and genetic study.

1983 • 86 citations

Cloning and regulation of messenger RNA for mouse apolipoprotein E.

1984 • 84 citations

Structure of the promoter of the rat type II procollagen gene.

1985 • 68 citations

Effect of dietary cholesterol on apolipoprotein E synthesis in the rabbit

1984 • 19 citations

Synthesis of rat apolipoprotein E by escherichia coli infected with recombinant bacteriophage

1984 • 19 citations