Atorvastatin Reduces Neurological Deficit and Increases Synaptogenesis, Angiogenesis, and Neuronal Survival in Rats Subjected to Traumatic Brain Injury

The rat nervous system

1985 • 3,774 citations

Therapeutic Benefit of Intravenous Administration of Bone Marrow Stromal Cells After Cerebral Ischemia in Rats

2001 • 1,642 citations

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

2000 • 1,427 citations

A controlled cortical impact model of traumatic brain injury in the rat

1991 • 1,123 citations

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

2002 • 1,074 citations

Clinical Trials in Head Injury

2002 • 891 citations

Human marrow stromal cell therapy for stroke in rat

2002 • 858 citations

Statins Have Biphasic Effects on Angiogenesis

2002 • 659 citations

Treatment of neural injury with marrow stromal cells

2002 • 621 citations

Mapping the body representation in the SI cortex of anesthetized and awake rats

1984 • 597 citations

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

2003 • 532 citations

Behavioral Tests After Intracerebral Hemorrhage in the Rat

2002 • 477 citations

HMG-CoA Reductase Inhibitors Improve Endothelial Dysfunction in Normocholesterolemic Hypertension via Reduced Production of Reactive Oxygen Species

2001 • 468 citations

Bone Marrow-Derived Endothelial Progenitor Cells Participate in Cerebral Neovascularization After Focal Cerebral Ischemia in the Adult Mouse

2002 • 452 citations

Ischaemic brain damage in fatal non-missile head injuries

1978 • 450 citations

A Model of Parasagittal Controlled Cortical Impact in the Mouse: Cognitive and Histopathologic Effects

1995 • 445 citations

Neuroprotective Properties of Statins in Cerebral Ischemia and Stroke

1999 • 394 citations

Atorvastatin Upregulates Type III Nitric Oxide Synthase in Thrombocytes, Decreases Platelet Activation, and Protects From Cerebral Ischemia in Normocholesterolemic Mice

2000 • 393 citations

A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia

2002 • 381 citations

Sustained Sensory/Motor and Cognitive Deficits With Neuronal Apoptosis Following Controlled Cortical Impact Brain Injury in the Mouse

1998 • 311 citations

Novel Pharmacologic Strategies in the Treatment of Experimental Traumatic Brain Injury: 1998

1998 • 298 citations

Treatment of Relapsing Paralysis in Experimental Encephalomyelitis by Targeting Th1 Cells through Atorvastatin

2003 • 281 citations

Correlation between Brain Reorganization, Ischemic Damage, and Neurologic Status after Transient Focal Cerebral Ischemia in Rats: A Functional Magnetic Resonance Imaging Study

2003 • 280 citations

Intravenous Administration of Human Umbilical Cord Blood Reduces Neurological Deficit in the Rat after Traumatic Brain Injury

2002 • 266 citations

A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats

2001 • 251 citations

Traumatic brain injury: physiology, mechanisms, and outcome

2004 • 216 citations

Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice

1999 • 209 citations

Enhanced Hippocampal Neurogenesis by Intraventricular S100B Infusion Is Associated with Improved Cognitive Recovery after Traumatic Brain Injury

2005 • 203 citations

Functional subdivisions of the rat somatic sensorimotor cortex

1990 • 183 citations

The Synaptophysin–Synaptobrevin Complex: a Hallmark of Synaptic Vesicle Maturation

1999 • 179 citations

Intracranial bone marrow transplantation after traumatic brain injury improving functional outcome in adult rats

2001 • 169 citations

Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats

2004 • 127 citations

Pravastatin Improves Cerebral Vasomotor Reactivity in Patients With Subcortical Small-Vessel Disease

2001 • 124 citations

Atorvastatin reduction of intravascular thrombosis, increase in cerebral microvascular patency and integrity, and enhancement of spatial learning in rats subjected to traumatic brain injury

2004 • 111 citations

Neuronal death after brain injury

1999 • 92 citations

Cholesterol, statins and dementia

2004 • 91 citations

HMG-CoA reductase inhibitors (statins) in the treatment of Alzheimer's disease and why it would be ill-advise to use one that crosses the blood-brain barrier.

2002 • 83 citations

Functional role of regrowing pyramidal tract fibers

1982 • 82 citations

Delayed Thrombosis after Traumatic Brain Injury in Rats

2004 • 74 citations

Atorvastatin stimulates the production of osteoprotegerin by human osteoblasts

2005 • 72 citations

Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization

2000 • 72 citations

Nitric Oxide and Angiogenesis in Cardiovascular Disease

2002 • 64 citations

Effect of atorvastatin on spatial memory, neuronal survival, and vascular density in female rats after traumatic brain injury

2005 • 59 citations

The Pathobiology of Traumatic Brain Injury

1997 • 57 citations

The Effects of Amphetamine on Recovery of Function after Cortical Damage in the Rat Depend on the Behavioral Requirements of the Task

1996 • 54 citations

Atorvastatin improves metabolic control and endothelial function in Type 2 diabetic patients: A placebo-controlled study

2003 • 48 citations

Atorvastatin reduction of intracranial hematoma volume in rats subjected to controlled cortical impact

2004 • 48 citations

High doses of simvastatin upregulate dopamine D₁ and D₂ receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase

2005 • 43 citations

Biologic Transplantation and Neurotrophin-Induced Neuroplasticity After Traumatic Brain Injury

2003 • 43 citations

Effects of atorvastatin on blood–brain barrier permeability during l-NAME hypertension followed by angiotensin-II in rats

2005 • 36 citations

Somatosensorimotor function of the superior colliculus, somatosensory cortex, and lateral hypothalamus in the rat

1987 • 34 citations