Limiting dilution analysis of helper T-cell function.

Statistical Methods for Research Workers

1945 • 11,140 citations

Antitrinitrophenyl (TNP) Plaque Assay. Primary Response of Balb/c Mice to Soluble and Particulate Immunogen

1969 • 935 citations

Is There Evidence for a Non-Antigen Specific Diffusable Chemical Mediator from the Thymus-Derived Cell in the Initiation of the Immune Response?**Supported by U. S. Public Health Service Research Grant AI-08795-03 and American Cancer Society Research Grant E-395-D.

1971 • 276 citations

Studies on Mouse Leukaemia. The Role of the Thymus in Leukaemogenesis by Cell-free Leukaemic Filtrates

1960 • 249 citations

Immunogenicity of Trinitrophenyl-Hemocyanin: Production of Primary and Secondary Anti-Hapten Precipitins

1966 • 248 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 162 citations

Induction of antibody‐forming cell clones in microcultures

1972 • 155 citations

CELL INTERACTIONS IN THE IMMUNE RESPONSE IN VITRO

1972 • 153 citations

INDUCTION OF A HEMOLYSIN RESPONSE IN VITRO

1970 • 126 citations

Precursor cells specific to sheep red cells in nude mice. estimation of frequency in the microculture system

1973 • 118 citations

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

1968 • 94 citations

T Cell-dependent Mediator in the Immune Response

1973 • 70 citations

When Allogeneic Mouse Spleen Cells Are Mixed in Vitro the T‐Cells Secrete a Product Which Guides the Maturation of B‐Cells

1972 • 67 citations

RESTRICTION OF THE CAPACITY TO RESPOND TO TWO ANTIGENS BY SINGLE PRECURSORS OF ANTIBODY-PRODUCING CELLS IN CULTURE

1969 • 64 citations

IMMUNOLOGICAL ADJUVANTS AND THE MECHANISM OF CELL COOPERATION

1972 • 63 citations

Mode of Action of a Supernatant Activity from T-Cell Cultures that Nonspecifically Stimulates the Humoral Immune Response

1974 • 54 citations

Specific heterologous enhancement of immune responses. 3. Partial characterization of supernatant material with enhancing activity.

1972 • 54 citations

A Model for the Interaction of Cell Types in the Generation of Hemolytic Plaque-Forming Cells

1970 • 49 citations

Enhancing Activity of Thymocyte Culture Cell-Free Medium on the in vitro Immune Response of Spleen Cells from Neonatally Thymectomized Mice to Sheep RBC

1972 • 46 citations

Soluble mediators of t‐b interaction

1973 • 46 citations

T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response.

1975 • 42 citations

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

1970 • 40 citations

The clonal nature of antibody formation. I. Clones of antibody-forming cells of poly-D-alanine specificity.

1970 • 35 citations

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

1969 • 34 citations

T cell-dependent mediator in the immune response. II. Physical and biological properties.

1974 • 33 citations

Clones of antibody‐forming cells in pokeweed mitogen‐stimulated microcultures. I. Requirements for the induction of the antibody response of nude spleen cells

1974 • 18 citations

Plaque-Forming Cells of Two Different Origins in Single Hemolytic Foci

1970 • 13 citations

Analysis of the limiting-dilution assay used for estimating frequencies of immunocompetent units

1974 • 13 citations

In vitro primary response in microcultures containing less than fifty thousand lymphoid cells

1973 • 10 citations

B CELL ACTIVATION IN VIVO BY NONANTIGEN-SPECIFIC INTERACTION WITH T CELLS

1972 • 5 citations

Equivalence of limiting dilution analysis and the hemolytic focus assay. Test of a prediction based on a model of cellular interaction between T and B cells.

1973 • 2 citations