Cutting Edge: Nociceptin Stimulates Neutrophil Chemotaxis and Recruitment: Inhibition by Aspirin-Triggered-15-Epi-Lipoxin A4

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1995 • 1,887 citations

ORL1, a novel member of the opioid receptor family

1994 • 1,060 citations

Effect of Neuropeptides on Production of Inflammatory Cytokines by Human Monocytes

1988 • 929 citations

A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration

1980 • 915 citations

A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration

1980 • 589 citations

Neurogenic vasodilatation and plasma leakage in the skin

1998 • 448 citations

Rapid quantitation of neutrophil chemotaxis: Use of a polyvinylpyrrolidone-free polycarbonate membrane in a multiwell assembly

1980 • 348 citations

Activation of Lipoxin a4 Receptors by Aspirin-Triggered Lipoxins and Select Peptides Evokes Ligand-Specific Responses in Inflammation

2000 • 262 citations

Primary structure and tissue distribution of the orphanin FQ precursor.

1996 • 251 citations

Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): A jungle of cell-cell interactions or a therapeutic opportunity?

1997 • 243 citations

Chemokine networks in vivo: involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-alpha.

1997 • 237 citations

Lipoxin (LX)A4 and Aspirin-triggered 15-epi-LXA4 Inhibit Tumor Necrosis Factor 1α–initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis

1999 • 198 citations

Structure-Activity Relationship Studies on the Novel Neuropeptide Orphanin FQ

1996 • 196 citations

Dialogue between the CNS and the immune system in lymphoid organs

1998 • 159 citations

Neurotransmitters of the sympathetic nerve terminal are powerful chemoattractants for monocytes

2000 • 131 citations

Expression and activity of prostaglandin endoperoxide synthase‐2 in agonist‐activated human neutrophils

1998 • 118 citations

Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice

1998 • 109 citations

Crystal‐induced neutrophil activation VI. Involvement of FcγRIIIB (CD16) and CD11b in response to inflammatory microcrystals

1998 • 101 citations

Aspirin and other anti-inflammatory drugs

2000 • 89 citations

Loss of Antinociception Induced by Naloxone Benzoylhydrazone in Nociceptin Receptor-Knockout Mice

1998 • 85 citations

Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system

1999 • 71 citations

Mast cells in newly formed lining tissue during acute inflammation: a six day air pouch model in the mouse.

1986 • 66 citations

LXA₄, aspirin-triggered 15-epi-LXA₄, and their analogs selectively downregulate PMN azurophilic degranulation

1999 • 66 citations

[Phe1Ψ(CH2-NH)Gly2]-nociceptin-(1-13)NH2, a proposed antagonist of the nociceptin receptor, is a potent and stable agonist in the rat spinal cord

1998 • 61 citations

Detection of substance P immunoreactivity in human peripheral leukocytes

1998 • 58 citations

“Turning Brain into Blood” — Clinical Applications of Stem-Cell Research in Neurobiology and Hematology

1999 • 35 citations

Peripheral non-opioid analgesic effects of kyotorphin in mice

1997 • 25 citations

Local and Systemic Delivery of an Aspirin-Triggered Lipoxin Stable Analog Inhibits Neutrophil Trafficking

2000 • 12 citations