Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

Parametric and nonparametric linkage analysis: a unified multipoint approach.

1996 • 2,905 citations

Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)

1996 • 1,607 citations

Allele-Sharing Models: LOD Scores and Accurate Linkage Tests

1997 • 993 citations

Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1)

1996 • 941 citations

Linkage strategies for genetically complex traits. II. The power of affected relative pairs.

1990 • 886 citations

Familial Hyperglycemia Due to Mutations in Glucokinase -- Definition of a Subtype of Diabetes Mellitus

1993 • 737 citations

A genome–wide search for human non–insulin–dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2

1996 • 601 citations

Development of a Novel Polygenic Model of NIDDM in Mice Heterozygous for IR and IRS-1 Null Alleles

1997 • 549 citations

Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families

1996 • 330 citations

On the statistical determination of major gene mechanisms in continuous human traits: Regressive models

1984 • 254 citations

Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits.

1993 • 175 citations

Two-locus maximum lod score analysis of a multifactorial trait: joint consideration of IDDM2 and IDDM4 with IDDM1 in type 1 diabetes.

1995 • 145 citations

Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.

1997 • 144 citations

Mutations in the Hepatocyte Nuclear Factor-1α/MODY3 Gene in Japanese Subjects With Early- and Late-Onset NIDDM

1997 • 93 citations

Joint linkage of multiple loci for a complex disorder.

1993 • 34 citations

Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1)

1999 • 19 citations

Linkage Analyses in Type I Diabetes mellitus Using CASPAR, a Software and Statistical Program for Conditional Analysis of Polygenic Diseases

1997 • 18 citations

Deleted Work

1955 • 0 citations