Monoclonal Antibodies to Murine Lipopolysaccharide (LPS)-Binding Protein (LBP) Protect Mice from Lethal Endotoxemia by Blocking Either the Binding of LPS to LBP or the Presentation of LPS/LBP Complexes to CD14

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

1990 • 4,041 citations

Structure and Function of Lipopolysaccharide Binding Protein

1990 • 1,689 citations

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS.

1994 • 435 citations

Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection

1997 • 354 citations

Identification of a Lipid A Binding Site in the Acute Phase Reactant Lipopolysaccharide Binding Protein

1989 • 351 citations

LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria.

1998 • 346 citations

Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein.

1995 • 268 citations

Lipopolysaccharide (LPS) Signal Transduction and Clearance

1995 • 260 citations

Recognition of endotoxin by cells leading to transmembrane signaling

1994 • 241 citations

Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids.

1997 • 232 citations

Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes.

1992 • 213 citations

Catalytic Properties of Lipopolysaccharide (LPS) Binding Protein

1996 • 198 citations

Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact

1997 • 179 citations

Lipopolysaccharide-binding protein and soluble CD14 transfer lipopolysaccharide to phospholipid bilayers: preferential interaction with particular classes of lipid.

1997 • 145 citations

The BPI/LBP family of proteins: A structural analysis of conserved regions

1998 • 144 citations

Lipopolysaccharide-binding protein as a major plasma protein responsible for endotoxemic shock.

1993 • 124 citations

CD14-mediated translocation of nuclear factor-kappa B induced by lipopolysaccharide does not require tyrosine kinase activity.

1994 • 120 citations

Plasma Lipopolysaccharide-binding Protein Is Found Associated with a Particle Containing Apolipoprotein A-I, Phospholipid, and Factor H-related Proteins

1996 • 100 citations

Mode of action of anti-lipopolysaccharide-binding protein antibodies for prevention of endotoxemic shock in mice.

1994 • 87 citations

An amino-terminal fragment of human lipopolysaccharide-binding protein retains lipid A binding but not CD14-stimulatory activity.

1994 • 85 citations

Stimulation of T-independent antibody responses by hapten-lipopolysaccharides without repeating polymeric structure

1979 • 55 citations

Two functionally independent pathways for lipopolysaccharide-dependent activation of mouse peritoneal macrophages.

1997 • 33 citations

Reactivity of murine and human recombinant LPS-binding protein (LBP) within LPS and gram negative bacteria.

1995 • 23 citations

Lipopolysaccharide and Its Analog Antagonists Display Differential Serum Factor Dependencies for Induction of Cytokine Genes in Murine Macrophages

1998 • 21 citations