BRCA2 Germline Mutations in Familial Pancreatic Carcinoma

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Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinase

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1998 • 426 citations

Germline and Somatic Mutations of the STK11/LKB1 Peutz-Jeghers Gene in Pancreatic and Biliary Cancers

1999 • 417 citations

Diabetes mellitus, other medical conditions and familial history of cancer as risk factors for pancreatic cancer

1999 • 398 citations

The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%

1996 • 385 citations

Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer.

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A Familial Syndrome of Pancreatic Cancer and Melanoma with a Mutation in theCDKN2Tumor-Suppressor Gene

1995 • 283 citations

Mutation analysis of the BRCA2 gene in 49 site–specific breast cancer families

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Inherited predisposition to pancreatic adenocarcinoma: role of family history and germ-line p16, BRCA1, and BRCA2 mutations.

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BRCA2 Is Inactivated Late in the Development of Pancreatic Intraepithelial Neoplasia

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Update of Familial Pancreatic Cancer in Germany

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