Synthesis of plus- and minus-strand RNA from poliovirion RNA template in vitro

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Methylmercury as a reversible denaturing agent for agarose gel electrophoresis

1976 • 1,323 citations

A New Method for the Large Scale Purification of Escherichia coli Deoxyribonucleic Acid-dependent Ribonucleic Acid Polymerase

1969 • 955 citations

Primary structure, gene organization and polypeptide expression of poliovirus RNA

1981 • 897 citations

Molecular cloning of poliovirus cDNA and determination of the complete nucleotide sequence of the viral genome.

1981 • 545 citations

A protein covalently linked to poliovirus genome RNA.

1977 • 424 citations

Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus.

1977 • 344 citations

Poliovirus-specific primer-dependent RNA polymerase able to copy poly(A).

1977 • 188 citations

Membrane-dependent uridylylation of the genome-linked protein VPg of poliovirus.

1983 • 157 citations

Identification of poliovirus polypeptide P63 as a soluble RNA-dependent RNA polymerase

1980 • 154 citations

Membrane fractions active in poliovirus RNA replication contain VPg precursor polypeptides

1983 • 136 citations

Dependence of the activity of the poliovirus replicase on a host cell protein

1980 • 129 citations

Characterization of poliovirus-specific structures associated with cytoplasmic membranes

1970 • 114 citations

Poliovirus Polyuridylic Acid Polymerase and RNA Replicase Have the Same Viral Polypeptide

1979 • 112 citations

Poliovirus replicase: a soluble enzyme able to initiate copying of poliovirus RNA.

1979 • 96 citations

Genome-linked protein VPg of poliovirus is present as free VPg and VPg-pUpU in poliovirus-infected cells.

1983 • 90 citations

Isolation of a Viral Polypeptide Associated with Poliovirus RNA Polymerase

1974 • 88 citations

Isolation of a soluble and template-dependent poliovirus RNA polymerase that copies virion RNA in vitro

1979 • 83 citations

Poliovirus replicase stimulation by terminal uridylyl transferase.

1985 • 71 citations

Poliovirus RNA-dependent RNA polymerase and host cell protein synthesize product RNA twice the size of poliovirion RNA in vitro

1985 • 68 citations

Genome-length copies of poliovirion RNA are synthesized in vitro by the poliovirus RNA-dependent RNA polymerase.

1982 • 64 citations

In vitro copying of viral positive strand RNA by poliovirus replicase. Characterization of the reaction and its products.

1982 • 64 citations

Purification of host factor required for in Vitro transcription of poliovirus RNA

1983 • 61 citations

Synthesis, cleavage and sequence analysis of DNA complementary to the 26 S messenger RNA of Sindbis virus

1981 • 61 citations

The host protein required for in vitro replication of poliovirus is a protein kinase that phosphorylates eukaryotic initiation factor-2

1985 • 58 citations

Purification and properties of a host cell protein required for poliovirus replication in vitro.

1982 • 56 citations

Comparison of replication complexes synthesizing poliovirus RNA

1981 • 50 citations

Poliovirus RNA-Dependent RNA Polymerase Synthesizes Full-Length Copies of Poliovirion RNA, Cellular mRNA, and Several Plant Virus RNAs In Vitro

1982 • 48 citations

Anti-VPg antibody inhibition of the poliovirus replicase reaction and production of covalent complexes of VPg-related proteins and RNA

1982 • 48 citations

Effect of Poliovirus Double-Stranded RNA on Viral and Host-Cell Protein Synthesis

1974 • 46 citations

The Reproduction of Picornaviruses

1974 • 40 citations

Secondary structure of poliovirus RNA: Correlation of computer-predicted with electron microscopically observed structure

1986 • 32 citations

Antibody to a synthetic nonapeptide corresponding to the NH2 terminus of poliovirus genome-linked protein VPg reacts with native VPg and inhibits in vitro replication of poliovirus RNA

1983 • 31 citations

ATP is required for initiation of poliovirus RNA synthesis in vitro: demonstration of tyrosine-phosphate linkage between in vitro-synthesized RNA and genome-linked protein

1984 • 31 citations

Antibody to poliovirus genome-linked protein (VPg) precipitates in vitro synthesized RNA attached to VPg-precursor polypeptide(s)

1984 • 23 citations

Antibody to a host protein prevents initiation by the poliovirus replicase

1982 • 14 citations