Effects of thalassemia and microcytosis on the hematologic and vasoocclusive severity of sickle cell anemia

Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease

1959 • 14,850 citations

Applied Multivariate Statistical Analysis.

1988 • 11,858 citations

Applied Regression Analysis and Other Multivariable Methods

1989 • 8,685 citations

Estimation of Small Percentages of Fœtal Hæmoglobin

1959 • 1,047 citations

Multivariate Analysis: With Applications in Education and Psychology.

1977 • 566 citations

Erythrocyte Adherence to Endothelium in Sickle-Cell Anemia

1980 • 524 citations

Kinetics and Mechanism of Deoxyhemoglobin S Gelation: A New Approach to Understanding Sickle Cell Disease

1974 • 497 citations

Insertion of synthetic copies of human globin genes into bacterial plasmids

1978 • 350 citations

The Interaction of Alpha-Thalassemia and Homozygous Sickle-Cell Disease

1982 • 306 citations

Concurrent Sickle-Cell Anemia and α-Thalassemia

1982 • 242 citations

Sickle-Cell Anemia: Molecular and Cellular Bases of Therapeutic Approaches

1978 • 241 citations

α-Globin gene organisation in blacks precludes the severe form of α-thalassaemia

1979 • 229 citations

The intracellular polymerization of sickle hemoglobin and its relevance to sickle cell disease

1981 • 216 citations

Identification of a Nondeletion Defect in α-Thalassemia

1977 • 194 citations

Requirements for therapeutic inhibition of sickle haemoglobin gelation

1978 • 138 citations

Lack of influence of fetal hemoglobin levels or erythrocyte indices on the severity of sickle cell anemia.

1980 • 105 citations

A New Genetic Basis for Hemoglobin-H Disease

1980 • 99 citations

Modulation of erythrocyte-endothelial interactions and the vasocclusive severity of sickling disorders

1981 • 99 citations

Hemoglobin Indianapolis (beta 112[G14] arginine). An unstable beta-chain variant producing the phenotype of severe beta-thalassemia.

1979 • 96 citations

Relatively Benign Sickle-cell Anaemia in 60 Patients Aged Over 30 in the West Indies

1968 • 95 citations

Determination of deoxyhemoglobin S polymer in sickle erythrocytes upon deoxygenation.

1980 • 91 citations

α-Thalassemia in the American Negro

1972 • 83 citations

A New Sickling Disorder Resulting from Interaction of the Genes for Haemoglobin S and α‐Thalassaemia

1969 • 81 citations

Alpha-thalassemia is related to prolonged survival in sickle cell anemia

1983 • 80 citations

Two types of triplicateda-globin loci in humans

1981 • 79 citations

Haematological factors associated with proliferative retinopathy in homozygous sickle cell disease.

1981 • 78 citations

Haematological factors associated with avascular necrosis of the femoral head in homozygous sickle cell disease

1982 • 76 citations

Clinical diversity of sickle cell anemia: Genetic and cellular modulation of disease severity

1983 • 76 citations

Comparison of Sickle Cell‐β° Thalassaemia with Homozygous Sickle Cell Disease

1979 • 74 citations

Mild sickle cell disease. Clinical and laboratory studies.

1973 • 61 citations

Rheology of Sickle Cells and Erythrocyte Content

1978 • 58 citations

NEGRO α-THALASSÆMIA IS CAUSED BY DELETION OF A SINGLE α-GLOBIN GENE

1979 • 50 citations

Sickle cell anemia as a rheologic disease

1981 • 49 citations

Benign Obstetric History in Women with Sickle-cell Anaemia Associated with -Thalassaemia

1972 • 44 citations

Clinical, hematologic and biosynthetic studies in sickle cell‐β°‐thalassemia: A comparison with sickle cell anemia

1976 • 30 citations

Sickle cell syndromes

1978 • 30 citations

The association of sickle cell anemia with heterozygous and homozygous α‐thalassemia‐2: In vitro HB chain synthesis

1979 • 29 citations

The effects of alpha‐thalassaemia in HbSC disease

1983 • 26 citations

Mapping the alpha-globin genes in an Algerian HbH patient and his family

1980 • 23 citations

Failure of the alpha-thalassemia gene to decrease the severity of sickle cell anemia

1978 • 21 citations

Red Cell Size and the Clinical and Haematological Features of Homozygous Sickle Cell Disease

1981 • 12 citations

Alpha thalassemia and homozygous sickle cell disease.

1981 • 8 citations

The effects of dromostanolone in sickle cell anemia

1974 • 5 citations