The OmpR protein of Escherichia coli binds to sites in the ompF promoter region in a hierarchical manner determined by its degree of phosphorylation.

Improved single and multicopy lac-based cloning vectors for protein and operon fusions

1987 • 1,537 citations

Physiological and genetic responses of bacteria to osmotic stress

1989 • 1,433 citations

DNA LOOPING

1992 • 408 citations

The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12

1981 • 329 citations

Influence of osmolarity of the growth medium on the outer membrane protein pattern of Escherichia coli

1977 • 326 citations

Genetic analysis of the ompB locus in Escherichia coli K-12

1981 • 301 citations

Mutations in a new chromosomal gene of Escherichia coli K-12, pcnB, reduce plasmid copy number of pBR322 and its derivatives

1986 • 263 citations

Phosphorylation of OmpR by the osmosensor EnvZ modulates expression of the ompF and ompC genes in Escherichia coli.

1989 • 258 citations

Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism.

1988 • 217 citations

EnvZ controls the concentration of phosphorylated OmpR to mediate osmoregulation of the porin genes

1991 • 186 citations

cis-acting ompF mutations that result in OmpR-dependent constitutive expression

1991 • 175 citations

Localization and membrane topology of EnvZ, a protein involved in osmoregulation of OmpF and OmpC in Escherichia coli.

1987 • 174 citations

A bacterial environmental sensor that functions as a protein kinase and stimulates transcriptional activation.

1989 • 152 citations

Evidence for the Physiological Importance of the Phosphotransfer between the Two Regulatory Components, EnvZ and OmpR, in Osmoregulation in Escherichia coli

1989 • 150 citations

Transcriptional regulation of Escherichia coli K-12 major outer membrane protein 1b

1979 • 139 citations

Phosphorylation of a Bacterial Activator Protein, OmpR, by a Protein Kinase, EnvZ, Results in Stimulation of Its DNA-Binding Ability1

1989 • 138 citations

DNA looping

1992 • 136 citations

Interaction of a transcriptional activator, OmpR, with reciprocally osmoregulated genes, ompF and ompC, of Escherichia coli.

1986 • 130 citations

Genetic analysis of the switch that controls porin gene expression in Escherichia coli K-12

1989 • 123 citations

Purification and characterization of the OmpR protein, a positive regulator involved in osmoregulatory expression of the ompF and ompC genes in Escherichia coli.

1986 • 104 citations

Identification of the DNA-binding domain of the OmpR protein required for transcriptional activation of the ompF and ompC genes of Escherichia coli by in vivo DNA footprinting

1989 • 94 citations

In vivo phosphorylation of OmpR, the transcription activator of the ompF and ompC genes in Escherichia coli

1990 • 85 citations

Interaction of OmpR, a positive regulator, with the osmoregulated ompC and ompF genes of Escherichia coli. Studies with wild-type and mutant OmpR proteins.

1988 • 85 citations

Regulation of ompC and ompF expression in Escherichia coli in the absence of envZ

1988 • 83 citations

Isolation and Characterization of Deletion Mutants of ompR and envZ, Regulatory Genes for Expression of the Outer Membrane Proteins OmpC and OmpF in Escherichia coli1

1987 • 76 citations

Static bend of DNA helix at the activator recognition site of the ompF promoter in Escherichia coli

1987 • 72 citations

cis-acting sites required for osmoregulation of ompF expression in Escherichia coli K-12

1986 • 64 citations

DNA-binding properties of the transcription activator (OmpR) for the upstream sequences of ompF in Escherichia coli are altered by envZ mutations and medium osmolarity

1989 • 57 citations

Transmembrane Signal Transduction and Osmoregulation in Escherichia coli: II. The Osmotic Sensor, EnvZ, Located in the Isolated Cytoplasmic Membrane Displays Its Phosphorylation and Dephosphorylation Abilities as to the Activator Protein, OmpR1

1990 • 53 citations

Altered osmoregulation of ompF in integration host factor mutants of Escherichia coli

1988 • 53 citations

Signal transduction and osmoregulation in Escherichia coli. A novel type of mutation in the phosphorylation domain of the activator protein, OmpR, results in a defect in its phosphorylation-dependent DNA binding

1991 • 53 citations

Transmembrane Signal Transduction and Osmoregulation in Escherichia coli: I. Analysis by Site-Directed Mutagenesis of the Amino Acid Residues Involved in Phosphotransfer between the Two Regulatory Components, EnvZ and OmpR1

1990 • 40 citations

Procaine, a local anesthetic, signals through the EnvZ receptor to change the DNA binding affinity of the transcriptional activator protein OmpR

1991 • 38 citations

Uncoupling of osmoregulation of the Escherichia coli K-12 ompF gene from ompB-dependent transcription

1985 • 31 citations

Phenotypic revertant mutations of a new OmpR2 mutant (V203Q) of Escherichia coli lie in the envZ gene, which encodes the OmpR kinase

1993 • 26 citations

Characterization of OmpR binding sequences in the upstream region of the ompF promoter essential for transcriptional activation

1989 • 26 citations

A dominant mutation in Escherichia coli OmpR lies within a domain which is highly conserved in a large family of bacterial regulatory proteins

1988 • 17 citations

Immunocytochemical Study of the Distribution of a Ganglioside in Sea Urchin Eggs1

1990 • 16 citations