Expression and specificity of human GM2 activator protein.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Lysosomes in biology and pathology

1977 • 2,068 citations

The Use of Sep‐Pak™ C₁₈ Cartridges During the Isolation of Gangliosides

1980 • 472 citations

Saposins: structure, function, distribution, and molecular genetics.

1992 • 323 citations

Studies on the Glycosidases of Jack Bean Meal

1970 • 309 citations

AB variant of infantile GM2 gangliosidosis: deficiency of a factor necessary for stimulation of hexosaminidase A-catalyzed degradation of ganglioside GM2 and glycolipid GA2.

1978 • 274 citations

Activator proteins and topology of lysosomal sphingolipid catabolism

1992 • 269 citations

Coding of Two Sphingolipid Activator Proteins (SAP-1 and SAP-2) by Same Genetic Locus

1988 • 251 citations

Molecular arrangements in sphingolipids. The crystal structure of cerebroside

1977 • 231 citations

Purification of Calf Prochymosin (Prorennin) Synthesized in Escherichia Coli

1984 • 227 citations

High-resolution proton NMR studies of gangliosides. 1. Use of homonuclear two-dimensional spin-echo J-correlated spectroscopy for determination of residue composition and anomeric configurations

1983 • 218 citations

Isolation and Structural Determination of a Novel Ganglioside, a Disialosylpentahexosylceramide from Human Brain

1973 • 183 citations

Purification and Characterization of an Activator Protein for the Degradation of Glycolipids G_M2and G_A2by Hexosaminidase A

1979 • 180 citations

An activator stimulating the enzymic hydrolysis of sphingoglycolipids.

1976 • 159 citations

Complexing of Glycolipids and Their Transfer between Membranes by the Activator Protein for Degradation of Lysosomal Ganglioside G_M2

1982 • 152 citations

Structure of Full-Length cDNA Coding for Sulfatide Activator, a Co-β-Glucosidase and Two Other Homologous Proteins: Two Alternate Forms of the Sulfatide Activator1

1989 • 134 citations

Hydrolysis of Tay-Sachs Ganglioside by β-Hexosaminidase A of Human Liver and Urine

1973 • 126 citations

Novel approach to the study of the antigenicities and receptor functions of carbohydrate chains of glycoproteins

1985 • 121 citations

The human GM2 activator protein. A substrate specific cofactor of beta-hexosaminidase A

1991 • 114 citations

The Precursor of Sulfatide Activator Protein is Processed to Three Different Proteins

1988 • 114 citations

Isolation and Characterization of Ceramide Glycanase from the Leech, Macrobdella decora

1989 • 98 citations

High Resolution Proton NMR Studies of Gangliosides

1989 • 93 citations

Characterization of a nonspecific activator protein for the enzymatic hydrolysis of glycolipids.

1988 • 92 citations

A protein activator for the enzymic hydrolysis of GM2 ganglioside.

1981 • 83 citations

NMR and computational studies of interactions between remote residues in gangliosides

1990 • 80 citations

The Protein Activator Specific for the Enzymic Hydrolysis of GM₂ Ganglioside in Normal Human Brain and Brains of Three Types of GM₂ Gangliosidosis

1983 • 72 citations

Deficiency of the Hexosaminidase A Activator Protein in a Case of GM2 Gangliosidosis; Variant AB

1982 • 68 citations

Over-expression of a functionally active human GM2-activator protein in Escherichia coli

1993 • 65 citations

[32] Labeled galactosyl ceramide and lactosyl ceramide

1972 • 61 citations

The gene coding for a sphingolipid activator protein, SAP-1, is on human chromosome 10

1985 • 61 citations

alpha-N-acetylgalactosaminidase from the limpet, Patella vulgata.

1977 • 61 citations

Isolation of a cDNA encoding the human G_M2 activator protein

1989 • 58 citations

Mapping of the gene coding for the human G_M2 activator protein to chromosome 5

1985 • 58 citations

Assignment of the gene for human sphingolipid activator protein-2 (SAP-2) to chromosome 10.

1985 • 41 citations

Fluorimetric assay of sialic acids

1976 • 37 citations

1H-NMR study of GM2 ganglioside: evidence that an interresidue amide-carboxyl hydrogen bond contributes to stabilization of a preferred conformation

1991 • 33 citations

Synthesis of neoglycoconjugates using oligosaccharide transferring activity of ceramide glycanase

1991 • 32 citations

Isolation and expression of a full-length cDNA encoding the human GM2 activator protein

1991 • 30 citations

A triple-binding-domain model explains the specificity of the interaction of a sphingolipid activator protein (SAP-1) with sulphatide, GM1-ganglioside and globotriaosylceramide

1986 • 25 citations

Evidence for two cDNA clones encoding human GM2-activator protein

1992 • 21 citations

[54] Protein activators for the hydrolysis of GM1 and GM2 gangliosides

1982 • 8 citations