Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS

A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12

1938 • 19,183 citations

A simple method of estimating 50 per cent end points

1938 • 8,381 citations

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

1993 • 1,005 citations

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

1988 • 540 citations

Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization

1994 • 527 citations

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

1988 • 514 citations

Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera

1990 • 416 citations

Broadly Neutralizing Antibodies Elicited by the Hypervariable Neutralizing Determinant of HIV-1

1990 • 358 citations

Variable and conserved neutralization antigens of human immunodeficiency virus

1986 • 296 citations

Introduction of site-specific mutations into the genome of influenza virus.

1990 • 247 citations

Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees

1990 • 230 citations

An engineered poliovirus chimaera elicits broadly reactive HIV-1 neutralizing antibodies

1989 • 222 citations

Characterization of HIV-1 neutralization escape mutants

1989 • 220 citations

Restricted neutralization of divergent human T-lymphotropic virus type III isolates by antibodies to the major envelope glycoprotein.

1986 • 204 citations

Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene

1988 • 186 citations

Virulence factors of influenza A viruses: WSN virus neuraminidase required for plaque production in MDBK cells

1977 • 143 citations

Long-Term High-Titer Neutralizing Activity Induced by Octameric Synthetic HIV-1 Antigen

1991 • 123 citations

Type-Restricted Neutralization of Molecular Clones of Human Immunodeficiency Virus

1988 • 115 citations

Complete sequence analysis shows that the hemagglutinins of the H0 and H2 subtypes of human influenza virus are closely related

1981 • 115 citations

An influenza A virus containing influenza B virus 5' and 3' noncoding regions on the neuraminidase gene is attenuated in mice.

1991 • 95 citations

In vitro generation of an HTLV-III variant by neutralizing antibody.

1986 • 79 citations

Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1

1993 • 75 citations

Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1

1992 • 74 citations

Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.

1993 • 69 citations

Generation of neutralization-resistant HIV-1 in vitro due to amino acid interchanges of third hypervariable env region.

1990 • 52 citations

Evaluation of monoclonal antibodies to HIV-1 by neutralization and serological assays

1991 • 50 citations

Evaluation of monoclonal antibodies to HIV-1 envelope by neutralization and binding assays

1994 • 35 citations

Long-term high-titer neutralizing activity induced by octameric synthetic HIV-1 antigen

1991 • 24 citations

Antisera raised against the second variable region of the external envelope glycoprotein of human immunodeficiency virus type 1 cross-neutralize and show an increased neutralization index when they act together with antisera to the V3 neutralization epitope

1993 • 17 citations