Molecular diversity in amino-terminal domains of human calpastatin by exon skipping.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

Dideoxy sequencing method using denatured plasmid templates

1986 • 1,537 citations

Calcium-activated neutral protease (calpain) system: structure, function, and regulation.

1991 • 841 citations

COMPLEX TRANSCRIPTIONAL UNITS: DIVERSITY IN GENE EXPRESSION BY ALTERNATIVE RNA PROCESSING

1986 • 486 citations

Nuclear and nucleolar targeting sequences of c-erb-A, c-myb, N-myc, p53, HSP70, and HIV tat proteins

1989 • 358 citations

Sequence requirements for nucleolar localization of human T cell leukemia virus type I pX protein, which regulates viral RNA processing

1988 • 308 citations

Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1

1991 • 305 citations

Calpain and calpastatin

1983 • 304 citations

Intracellular Calcium-Dependent Proteolysis

2019 • 286 citations

Gene expression of fibroblast growth factors in human gliomas and meningiomas: demonstration of cellular source of basic fibroblast growth factor mRNA and peptide in tumor tissues.

1990 • 279 citations

Human fibronectin: cell specific alternative mRNA splicing generates polypeptide chains dfffering in the number of internal repeats

1984 • 221 citations

Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites.

1984 • 202 citations

Pig heart calpastatin: identification of repetitive domain structures and anomalous behavior in polyacrylamide gel electrophoresis

1988 • 190 citations

Calculation of the isoelectric points of polypeptides from the amino acid composition

1986 • 185 citations

Differential splicing of Alzheimer's disease amyloid A4 precursor RNA in rat tissues: PreA4695 mRNA is predominantly produced in rat and human brain

1990 • 183 citations

Endogenous inhibitor for calcium-dependent cysteine protease contains four internal repeats that could be responsible for its multiple reactive sites.

1987 • 164 citations

Calpain II Involvement in Mitosis

1988 • 163 citations

The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors

1991 • 151 citations

Inhibition of calpain by a synthetic oligopeptide corresponding to an exon of the human calpastatin gene

1989 • 142 citations

All four internally repetitive domains of pig calpastatin possess inhibitory activities against calpains I and II

1987 • 104 citations

Calcium activated neutral protease. - Structure-function relationship and functional implications.

1990 • 96 citations

A possible physiological role of the Ca-dependent protease calpain and its inhibitor calpastatin on the Ca current in guinea pig myocytes

1988 • 85 citations

Effects of alternate RNA splicing on glucokinase isoform activities in the pancreatic islet, liver, and pituitary.

1991 • 79 citations

Calpastatin and nucleotides stabilize cardiac calcium channel activity in excised patches

1991 • 65 citations

cDNA Cloning of Human Calpastatin: Sequence Homology Among Human, Pig, and Rabbit Calpastatins

1989 • 62 citations

Phosphorylation and subcellular distribution of calpastatin in human hematopoietic system cells

1991 • 58 citations

Alternative splicing of human synexin mRNA in brain, cardiac, and skeletal muscle alters the unique N-terminal domain.

1991 • 55 citations

Lethal neurotoxicity in mice of the basic domains of HIV and SIV Rev proteins Study of these regions by circular dichroism

1991 • 50 citations

Calcium-activated neutral protease inhibitor from rabbit erythrocytes lacks the N-terminal region of the liver inhibitor but retains three inhibitory units

1987 • 38 citations

Rat calpastatin has diverged primary sequence from other mammalian calpastatins but retains functionality important sequences

1991 • 38 citations

Multiple forms of rat calpastatin cDNA in the coding region of functionally unknown amino-terminal domain

1992 • 27 citations

The binding of large calpastatin to biologic membranes is mediated in part by interaction of an amino terminal region with acidic phospholipids

1989 • 27 citations

On the mechanism of binding of calpastatin, the protein inhibitor of calpains, to biologic membranes

1988 • 25 citations

Assignment of the human calpastatin gene (CAST) to chromosome 5 at region q14→q22

1990 • 19 citations

Direct measurement of calpastatin subtypes by sandwich enzyme immunoassay using monoclonal antibodies

1991 • 10 citations