Nucleotide sequence of the fadA gene. Primary structure of 3-ketoacyl-coenzyme A thiolase from Escherichia coli and the structural organization of the fadAB operon.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Construction of Phylogenetic Trees

1967 • 3,637 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Molecular evolutionary genetics

1987 • 2,362 citations

Fluorescence detection in automated DNA sequence analysis

1986 • 1,694 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

One-step preparation of competent Escherichia coli: transformation and storage of bacterial cells in the same solution.

1989 • 1,585 citations

The neutral theory of molecular evolution

1984 • 1,459 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA.

1988 • 775 citations

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

1986 • 717 citations

Use of the ‘Perceptron’ algorithm to distinguish translational initiation sites inE. coli

1982 • 660 citations

Rat liver peroxisomes catalyze the beta oxidation of fatty acids.

1978 • 608 citations

Fatty Acid Degradation in Escherichia coli

1969 • 351 citations

Effect of Growth Conditions on the Formation of the Relaxation Complex of Supercoiled ColE1 Deoxyribonucleic Acid and Protein in Escherichia coli

1972 • 351 citations

Poly-β-hydroxybutyrate biosynthesis in Alcaligenes eutrophus H16

1989 • 334 citations

The Presence of a New 3‐Oxoacyl‐CoA Thiolase in Rat Liver Peroxisomes

1980 • 196 citations

Simple method for constructing phylogenetic trees from distance matrices.

1981 • 173 citations

Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase.

1987 • 159 citations

Nucleotide sequence of naturally occurring deletion mutants of cauliflower mosaic virus

1981 • 139 citations

A molecular view of fatty acid catabolism in Escherichia coli

1986 • 138 citations

Microbodies in the Living Cell

1983 • 122 citations

Fatty acid oxidation in rat brain is limited by the low activity of 3-ketoacyl-coenzyme A thiolase.

1987 • 122 citations

Purification and properties of a pig heart thiolase with broad chain length specificity and comparison of thiolases from pig heart and Escherichia coli.

1978 • 115 citations

Properties of Peroxisomal 3-Ketoacyl-CoA Thiolase from Rat Liver1

1981 • 98 citations

Mechanistic studies on .beta.-ketoacyl thiolase from Zoogloea ramigera: identification of the active-site nucleophile as Cys89, its mutation to Ser89, and kinetic and thermodynamic characterization of wild-type and mutant enzymes

1989 • 98 citations

Biosynthetic thiolase from Zoogloea ramigera. III. Isolation and characterization of the structural gene.

1987 • 94 citations

ato Operon: a Highly Inducible System for Acetoacetate and Butyrate Degradation in Escherichia coli

1972 • 92 citations

cDNA-derived amino acid sequence of rat mitochondrial 3-oxoacyl-CoA thiolase with no transient presequence: structural relationship with peroxisomal isozyme.

1987 • 75 citations

The structure of the multienzyme complex of fatty acid oxidation from Escherichia coli.

1981 • 69 citations

Isolation of a multi-enzyme complex of fatty acid oxidation from Escherichia coli.

1977 • 58 citations

The large subunit of the fatty acid oxidation complex from Escherichia coli is a multifunctional polypeptide. Evidence for the existence of a fatty acid oxidation operon (fad AB) in Escherichia coli.

1983 • 57 citations

Evidence that the fadB gene of the fadAB operon of Escherichia coli encodes 3-hydroxyacyl-coenzyme A (CoA) epimerase, delta 3-cis-delta 2-trans-enoyl-CoA isomerase, and enoyl-CoA hydratase in addition to 3-hydroxyacyl-CoA dehydrogenase

1988 • 53 citations

Molecular Cloning and Nucleotide Sequence of cDNA Encoding the Entire Precursor of Rat Mitochondrial Acetoacetyl-CoA Thiolase1

1989 • 51 citations

[17] 3-Ketoacyl-CoA thiolases of mammalian tissues

1975 • 47 citations

Molecular and catalytic properties of the acetoacetyl-coenzyme A thiolase of Escherichia coli

1976 • 46 citations

Utility of the gas-phase sequencer for both liquid- and solid-phase degradation of proteins and peptides at low picomole levels

1984 • 42 citations

The Active Site Cysteines of Thiolase

1970 • 39 citations

Cloning, mapping, and expression of genes involved in the fatty acid-degradative multienzyme complex of Escherichia coli

1984 • 39 citations

A noncleavable signal for mitochondrial import of 3-oxoacyl-CoA thiolase.

1988 • 36 citations

Cloning, sequencing and analysis of the yeastS. uvarum ERG10 gene encoding acetoacetyl CoA thiolase

1988 • 34 citations

Peroxisomal Acetoacetyl-CoA Thiolase and 3-Ketoacyl-CoA Thiolase from an n-Alkane-Utilizing Yeast, Candida tropicalis: Purification and Characterization1

1989 • 31 citations

Proton transfer from acetyl-coenzyme A catalyzed by thiolase I from porcine heart

1981 • 29 citations

Complete cDNA sequence of human foetal liver peroxisomal 3-oxoacyl-CoA thiolase

1989 • 25 citations

4-Bromo-2-octenoic acid specifically inactivates 3-ketoacyl-CoA thiolase and thereby fatty acid oxidation in rat liver mitochondria

1988 • 16 citations