Molecular cloning of cDNA for rat L-type pyruvate kinase and aldolase B.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Methylmercury as a reversible denaturing agent for agarose gel electrophoresis

1976 • 1,323 citations

Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels

1979 • 564 citations

Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation.

1979 • 501 citations

[103a] The use of guanidinium chloride in the isolation of nucleic acids

1968 • 494 citations

Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.

1979 • 484 citations

The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit β-globin DNA

1981 • 473 citations

Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase

1978 • 426 citations

Synthesis of double-stranded DNA complementary to lysozyme, ovomucoid, and ovalbumin mRNAs. Optimization for full length second strand synthesis by Escherichia coli DNA polymerase I.

1978 • 395 citations

Multimolecular Forms of Pyruvate Kinase from Rat and Other Mammalian Tissues*

1972 • 359 citations

Primary activation of the vitellogenin gene in the rooster.

1977 • 353 citations

Enzymatic in vitro synthesis of globin genes

1976 • 343 citations

Isozymes current topics in biological and medical research

1984 • 328 citations

Studies on the selectivity of DNA precipitation by spermine

1981 • 267 citations

Molecular cloning of a human histocompatibility antigen cDNA fragment.

1980 • 145 citations

Anomalie de l’aldolase hépatique dans l’intolérance au fructose

1961 • 140 citations

Increased amplification of pBR322 plasmid deoxyribonucleic acid in Escherichia coli K-12 strains RR1 and chi1776 grown in the presence of high concentrations of nucleoside

1979 • 140 citations

Cloning of cDNA for argininosuccinate synthetase mRNA and study of enzyme overproduction in a human cell line.

1981 • 135 citations

Molecular cloning of cDNA for the alpha, beta, and gamma chains of rat fibrinogen. A family of coordinately regulated genes.

1981 • 129 citations

A general method for detection and characterization of an mRNA using an oligonucleotide probe.

1981 • 128 citations

Enzymes Involved in Fructose Metabolism in Liver and the Glyceraldehyde Metabolic Crossroads

1969 • 127 citations

Anomaly of Aldolase in Primary Liver Cancer

1963 • 126 citations

Expression and methylation of the mouse alpha-fetoprotein gene in embryonic, adult, and neoplastic tissues.

1982 • 119 citations

Purification of low-abundance messenger RNAs from rat liver by polysome immunoadsorption.

1982 • 119 citations

Isozymes And Cancer

1973 • 113 citations

ALDOLASE VARIANTS: STRUCTURE AND PHYSIOLOGICAL SIGNIFICANCE*

1968 • 108 citations

cDNA clones for the heavy chain of HLA-DR antigens obtained after immunopurification of polysomes by monoclonal antibody.

1982 • 107 citations

Studies on Pyruvate Kinase (PK) Deficiency

1973 • 103 citations

[3] Addition of homopolymers to the 3′-ends of duplex DNA with terminal transferase

1979 • 101 citations

Changes in the frequency of specific transcripts during development of the pancreas.

1977 • 95 citations

Identification of cDNA clones coding for rat tyrosine hydroxylase antigen.

1982 • 94 citations

Dietary and Hormonal Regulation of Enzymes of Fructose Metabolism in Rat Liver

1966 • 91 citations

Cell‐Free Translation of Messenger RNAs from Adult and Fetal Human Muscle

1981 • 81 citations

One gene, but two messenger RNAs encode liver L and red cell L′ pyruvate kinase subunits

1981 • 80 citations

Regulation of Rat Liver L‐Type Pyruvate Kinase mRNA by Insulin and by Fructose

1982 • 78 citations

αA-Crystallin Messenger RNA of the Mouse Lens: More Noncoding Than Coding Sequences

1982 • 78 citations

Pyruvate Kinase Isozymes from Rat Tissues

1973 • 67 citations

Probable nuclear precursors of preprolactin mRNA in rat pituitary cells.

1981 • 62 citations

Liver pyruvate kinase (PK) isozymes in a PK‐deficient patient*

1968 • 56 citations

[23] Pyruvate kinases from human erythrocytes and liver

1982 • 52 citations

Amino acid sequence at the phosphorylated site of rat liver pyruvate kinase

1975 • 50 citations

Pyruvate kinase isozymes in man

1976 • 48 citations

[34] Maximizing gene expression on a plasmid using recombination in Vitro

1979 • 40 citations

Chronic Haemolytic Anaemia in Two Patients Heterozygous for Erythrocyte Pyruvate Kinase Deficiency

1976 • 38 citations

[38] Detection and isolation of mammalian fructose-diphosphate aldolases

1975 • 38 citations

Dietary alteration of translatable mRNA sequences coding for rat liver pyruvate kinase.

1980 • 34 citations

Characterization of messenger RNA for aldolase B in adult and fetal human liver

1982 • 31 citations

Construction of bacterial plasmids containing sequences complementary to chicken α-tropomyosin mRNA

1981 • 29 citations

Characterization of pyruvate kinase from the liver of a patient with aberrant erythrocyte pyruvate kinase, PK Nagasaki.

1977 • 25 citations

A new pyruvate kinase variant (PK Osaka) demonstrated by partial purification and condensation.

1976 • 24 citations

The induction of synthesis of L-type pyruvate kinase in cultured rat hepatocytes

1982 • 24 citations

Extreme deficiency of L-type pyruvate kinase with moderate clinical expression

1982 • 23 citations

Two different species of messenger RNAs specify synthesis of M1 and M2 pyruvate kinase subunits

1982 • 23 citations

Unusually long mRNA species coding for human alpha and beta interferons.

1982 • 22 citations

Isoelectrofocusing of aldolase B from normal human livers and from livers with hereditary fructose intolerance

1977 • 18 citations

Cotranslation of L and L′ pyruvate kinase messenger RNAs from human fetal liver

1982 • 17 citations

Cell free synthesis of human prothrombin: Immunological characterization of the translation product

1981 • 16 citations

Enzyme des Fructosestoffwechsels. Änderungen von Enzymaktivitäten in Leber und Niere der Ratte bei fructose- und glucosereicher Ernährung

1968 • 15 citations

Long-term modulation of type L pyruvate kinase activity in young and mature rats

1982 • 12 citations

Molecular organization of human L′ and L pyruvate kinases

1982 • 8 citations