Telomere stability is frequently impaired in high-risk groups of patients with myelodysplastic syndromes.

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes

1997 • 4,416 citations

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

1985 • 3,331 citations

A survey of telomerase activity in human cancer

1997 • 2,747 citations

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

1988 • 2,281 citations

Telomere length predicts replicative capacity of human fibroblasts.

1992 • 2,209 citations

Solid Cancers after Bone Marrow Transplantation

1997 • 950 citations

Activation of telomerase in human lymphocytes and hematopoietic progenitor cells.

1995 • 871 citations

Myelodysplastic syndromes: a scoring system with prognostic significance

1985 • 526 citations

Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes [see comments]

1995 • 445 citations

Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)

1995 • 395 citations

Telomerase Regulation, Cell Cycle, and Telomere Stability in Primitive Hematopoietic Cells

1997 • 273 citations

Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals

1998 • 258 citations

Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants

1998 • 236 citations

Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions.

1995 • 191 citations

Clinical implications of chromosomal abnormalities in 401 patients with myelodysplastic syndromes: a multicentric study in Japan.

1993 • 174 citations

Fas/Apo-1(CD95) expression and apoptosis in patients with myelodysplastic syndromes

1997 • 169 citations

Telomere shortening associated with disease evolution patterns in myelodysplastic syndromes.

1994 • 130 citations

Telomere dynamics and genome instability in human cancer

1995 • 129 citations

Cytological detection of telomerase activity using an in situ telomeric repeat amplification protocol assay.

1997 • 97 citations

Telomere length in myelodysplastic syndromes

1997 • 86 citations

Clinical implications of telomerase activity levels in acute leukemia.

1997 • 85 citations

Changes of telomere length in children after hematopoietic stem cell transplantation

1998 • 84 citations

Telomere Crisis, the Driving Force in Cancer Cell Evolution

1997 • 70 citations

The relationship between telomere length and therapy-associated cytogenetic responses in patients with chronic myeloid leukemia

1997 • 61 citations

A nonradioactive, fluorescence-based telomeric repeat amplification protocol to detect and quantitate telomerase activity

1996 • 45 citations

Replication errors in hematological neoplasias: genomic instability in progression of disease is different among different types of leukemia.

1996 • 28 citations