Purification of a 130-kDa T cell glycoprotein that binds human interleukin 4 with high affinity.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities.

1986 • 514 citations

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

1988 • 509 citations

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1987 • 449 citations

Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.

1986 • 355 citations

Recombinant interleukin 4 promotes the growth of human T cells.

1987 • 252 citations

Characterization of the human B cell stimulatory factor 1 receptor.

1987 • 232 citations

Molecular Biology of Interleukin 4 and Interleukin 5 Genes and Biology of their Products that Stimulate B Cells, T Cells and Hemopoietic Cells

1988 • 211 citations

B cell growth-promoting activity of recombinant human interleukin 4.

1987 • 211 citations

IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures.

1988 • 167 citations

Interleukin-4 mediates CDS induction on human CD4+ T-cell clones

1988 • 163 citations

Characterization of the high-affinity cell-surface receptor for murine B-cell-stimulating factor 1.

1987 • 140 citations

Regulation of cytolytic cell populations from human peripheral blood by B cell stimulatory factor 1 (interleukin 4).

1987 • 137 citations

Interleukin 4 counteracts the interleukin 2-induced proliferation of monoclonal B cells.

1988 • 130 citations

Inhibitory influence of IL-4 on human B cell responsiveness.

1988 • 123 citations

Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM.

1988 • 119 citations

Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2.

1988 • 100 citations

Purification of human gamma interferon receptors by sequential affinity chromatography on immobilized monoclonal antireceptor antibodies and human gamma interferon.

1987 • 95 citations

High affinity binding of human interleukin 4 to cell lines

1987 • 70 citations

Internalization of Human Interleukin 4 and Transient Down-regulation of Its Receptor in the CD23-inducible Jijoye Cells

1989 • 62 citations

Human interleukin 4 down‐regulates the surface expression of CD5 on normal and leukemic B cells

1989 • 58 citations

Isolation and characterization of multiple variants of recombinant human interleukin 4 expressed in mammalian cells.

1988 • 53 citations

Phorbol ester and calcium ionophore are sufficient to promote cell replication in cultures of quiescent human B lymphocytes.

1989 • 13 citations