Vitamin E and immunity

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

1961 • 3,579 citations

Secretory products of macrophages.

1987 • 2,670 citations

Development of a Strain of Spontaneously Hypertensive Rats

1963 • 2,492 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

1990 • 960 citations

A new murine model of accelerated senescence

1981 • 855 citations

The functional relationship of the interleukins.

1980 • 660 citations

Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects

1990 • 581 citations

VITAMIN E AND FREE RADICAL PEROXIDATION OF LIPIDS*

1972 • 471 citations

Prostaglandin E inhibits the production of human interleukin 2.

1982 • 423 citations

Macrophages and metastasis--a biological approach to cancer therapy.

1985 • 354 citations

Nutrition and immunology

1988 • 314 citations

Vitamin E supplementation suppresses prostaglandin E21 synthesis and enhances the immune response of aged mice

1986 • 275 citations

Prostaglandin Suppression of Mitogen-Stimulated Lymphocytes In Vitro

1978 • 258 citations

Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors.

1988 • 257 citations

Autooxidation as a basis for altered function by polymorphonuclear leukocytes

1977 • 237 citations

Retrovirus-induced immunodeficiency in the mouse

1992 • 221 citations

Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells.

1993 • 212 citations

Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro.

1994 • 197 citations

Tocopherol, oxygen and biomembranes

1978 • 194 citations

Antioxidant status and lipid peroxidation in patients infected with HIV

1994 • 191 citations

Enumeration of T lymphocyte subsets by monoclonal antibodies in young and aged humans.

1981 • 187 citations

Thymic Involution: Effect on T Cell Differentiation

1975 • 183 citations

Antioxidant Micronutrients and Immune Responses

1990 • 179 citations

Secretion of oxygen intermediates: role in effector functions of activated macrophages.

1982 • 146 citations

Tocopherol, Oxygen and Biomembranes

1978 • 144 citations

Dietary Vitamin E Requirement for Optimum Immune Responses in the Rat

1986 • 141 citations

Nutrition, Immunity and Illness in the Elderly

1986 • 140 citations

Recent Developments in Vitamin E and Immune Response

2009 • 138 citations

The differential effects of human leukocyte pyrogen/lymphocyte-activating factor, T cell growth factor, and interferon on human natural killer activity.

1982 • 138 citations

Suppression of human immunodeficiency virus replication by ascorbate in chronically and acutely infected cells.

1990 • 137 citations

Radiation Effects on Membranes: I. Vitamin E Deficiency and Lipid Peroxidation

1979 • 134 citations

Prostaglandin E₂ and the increase of intracellular cAMP inhibit the expression of interleukin 2 receptors in human T cells

1988 • 129 citations

Influence of vitamin E and selenium on immune response mechanisms.

1979 • 128 citations

Suppression of natural killing in vitro by monocytes and polymorphonuclear leukocytes: requirement for reactive metabolites of oxygen.

1982 • 126 citations

Protection of Liposomal Lipids against Radiation Induced Oxidative Damage

1979 • 118 citations

Immune function in aged women is improved by ingestion of vitamins C and E

1998 • 115 citations

Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol.

1977 • 110 citations

Vitamin E and immune response. I. Enhancement of helper T cell activity by dietary supplementation of vitamin E in mice.

1979 • 108 citations

Enhancement of the Humoral Immune Response by Vitamin E

1973 • 108 citations

Immunomodulation by neutrophil myeloperoxidase and hydrogen peroxide: differential susceptibility of human lymphocyte functions.

1986 • 104 citations

Identification of early stages of T lymphocyte development in the thymus cortex and medulla.

1985 • 103 citations

High Dietary Intakes of Vitamin E and Cellular Immune Functions in Rats

1990 • 100 citations

Immunological depression in spontaneously hypertensive rats.

1980 • 95 citations

Phagocyte Function in the Neonate: Selected Aspects

1979 • 95 citations

Nutritional Status and Immune Responses in Mice with Murine AIDS Are Normalized by Vitamin E Supplementation

1994 • 91 citations

Function of 2-Mercaptoethanol as a Macrophage Substitute in the Primary Immune Response in Vitro

1976 • 90 citations

Some antioxidants inhibit, in a co-ordinate fashion, the production of tumor necrosis factor-α, IL-β, and IL-6 by human peripheral blood mononuclear cells

1994 • 86 citations

Radiation effects on DNA. The Silvanus Thompson Memorial Lecture, April 1982

1983 • 81 citations

Vitamin E deficiency and impaired cellular immunity related to intestinal fat malabsorption

1992 • 79 citations

Effect of Vitamin E on the Immune Response of Hypoxic and Normal Chickens

1972 • 74 citations

Role of vitamin E in the protection of the resident macrophage membrane against oxidative damage.

1986 • 70 citations

Effect of 3 months vitamin E supplementation on indices of the cellular and humoral immune response in elderly subjects

1997 • 65 citations

Nutrition factors in relation to cellular and regulatory immune variables in a free-living elderly population

1990 • 64 citations

Characterization of immunological depression in spontaneously hypertensive rats

1981 • 59 citations

Relationship between megadose vitamin supplementation and immunological function in a healthy elderly population.

1983 • 58 citations

Minireview Murine models for Acquired Immune Deficiency Syndrome

1989 • 57 citations

Effect of Vitamin E as an Immunopotentiation Agent for Mice at Optimal Dosage and Its Toxicity at High Dosage

1982 • 55 citations

Long-Term Feeding of High Vitamin E Diet Improves the Decreased Mitogen Response of Rat Splenic Lymphocytes with Aging.

1997 • 53 citations

The potential role of nutritional factors in the induction of immunologic abnormalities in HIV-positive homosexual men.

1989 • 52 citations

Hemolytic Anemia in Vitamin E Deficiency

1968 • 51 citations

Mechanism of the age-related decline in lymphocyte proliferation: Role of IL-2 production and protein synthesis

1983 • 47 citations

Prostaglandins as regulators in cellular immunity

1978 • 47 citations

Antioxidant vitamins and immune responses

1988 • 46 citations

Natural cytotoxic autoantibody against thymocytes in spontaneously hypertensive rats

1981 • 46 citations

Immunological Depression in Spontaneously Hypertensive Rats

1980 • 45 citations

Antioxidant Effects on Cell-Mediated Immunity

1985 • 45 citations

Vitamin E Is an Important Factor in T Cell Differentiation in Thymus of F344 Rats.

1993 • 44 citations

Reduced effect of irradiation on normal and malignant cells irradiatedin vivoin mice pretreated with vitamin E

1973 • 43 citations

Ageing, nutritional status and immune response.

1998 • 42 citations

Influence of Diet on Experimental Swine Dysentery

1978 • 42 citations

Effects of dietary vitamin E on the biosynthesis of 5-lipoxygenase products by rat polymorphonuclear leukocytes (PMNL)

1989 • 42 citations

Proliferation of thymic stem cells with and without receptors for interleukin 2. Implications for intrathymic antigen recognition.

1985 • 41 citations

Effects of Dietary Restriction on Age-Related Immune Dysfunction in the Senescence Accelerated Mouse (SAM)

1990 • 39 citations

Effect of etoposide (VP16-213) on lipid peroxidation and antioxidant status in a high-dose radiochemotherapy regimen

1989 • 39 citations

Long-Term Dietary Vitamin E Retards Development of Retrovirus-Induced Disregulation in Cytokine Production

1994 • 38 citations

The Effect of Vitamin E on the Cell‐mediated Immune Response in Pigs

1988 • 38 citations

Effect of vitamin E deficiency on the proliferative response of canine lymphocytes.

1981 • 36 citations

Zidovudine (azido dideoxythymidine) inhibits characteristic early alterations of lymphoid cell populations in retrovirus-induced murine AIDS.

1990 • 32 citations

The potential role of vitamin E in the treatment of immunologic abnormalities during acquired immune deficiency syndrome.

1991 • 31 citations

Analysis of thymic stromal cell subpopulations grown in vitro on extracellular matrix in defined medium. II. Cytokine activities in murine thymic epithelial and mesenchymal cell culture supernatants.

1990 • 29 citations

The effect of vitamin E on cellular survival after X irradiation of lymphoma cells

1978 • 29 citations

Requirement for prooxidant and antioxidant states in T cell mediated immune responses. — Relevance for the pathogenetic mechanism of AIDS?

1991 • 28 citations

Metabolism and Physiologic Roles of Vitamin E

1977 • 26 citations

Elevated macrophage activity in nude mice.

1984 • 24 citations

Effects of RRR‐α‐tocopheryl succinate on il‐1 and PGE₂production by macrophages

1993 • 22 citations

Lipid peroxidation during chronic inflammation induced in rats by Freund's adjuvant: effect of vitamin E as measured by expired pentane.

1982 • 20 citations

Effect of β‐carotene on spontaneous and x‐ray‐induced chromosomal damage in bone marrow cells of mice

1994 • 19 citations

Effects of vitamin E deficiency on the functions of splenic lymphocytes and alveolar macrophages.

1989 • 15 citations

Vitamin E enhances T cell differentiation through increased epithelial cell function in rat thymus

1997 • 15 citations

Suppression of Human Immunodeficiency Virus Replication by Ascorbate in Chronically and Acutely Infected Cells

1990 • 14 citations

Elevated Macrophage Activity in Nude Mice

1984 • 13 citations

Vitamin E prevents the decrease of cellular immune function with aging in spontaneously hypertensive rats

1995 • 12 citations

The Role of Macrophages in Increased Mitogen Response of Rat Splenic Lymphocytes Following in Vitro Incubation with Vitamin E.

1995 • 11 citations

Effect of vitamin E supplementation on cellular immune functions decreased with aging in spontaneously hypertensive rats

1993 • 10 citations

Anemia in Infancy: Iron Deficiency and Vitamin E Deficiency

1980 • 7 citations

Effect of vitamin E on oxidative metabolism of macrophages

1986 • 6 citations

Vitamin E supplementation induces an early recovery of cellular immunity decreased following X-ray irradiation

1996 • 6 citations

Vitamin E supplementation normalizes immune dysfunction in murine AIDS induced by LP-BM5 retrovirus infection

1996 • 4 citations

Decreased mitogen response of splenocytes in senescence accelerated mice (SAM-P1) is not restored by high vitamin E diet

1999 • 4 citations

[Vitamin E is beneficial for the immune system in the elderly].

1998 • 2 citations

[Effect of vitamin E on the oxidative metabolism of macrophages].

1986 • 2 citations