Forms of pp60v-src isolated from Rous sarcoma virus-transformed cells

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Die Molekularbiologie der Tumorviren

1977 • 951 citations

Identification of a transformation-specific antigen induced by an avian sarcoma virus

1977 • 931 citations

A one-step purification of membrane proteins using a high efficiency immunomatrix.

1982 • 782 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

1980 • 510 citations

A rapid purification of alpha-actinin, filamin, and a 130,000-dalton protein from smooth muscle.

1980 • 395 citations

Neurones express high levels of a structurally modified, activated form of pp60c-src

1985 • 372 citations

Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).

1981 • 363 citations

Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation.

1982 • 337 citations

Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation

1984 • 333 citations

Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylation

1979 • 319 citations

Cell Transformation by RNA Tumor Viruses

1977 • 298 citations

Identification of a polypeptide encoded by the avian sarcoma virus src gene.

1978 • 266 citations

Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product

1978 • 251 citations

Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinase.

1979 • 232 citations

Construction and analysis of in vivo activity of E. coll promoter hybrids and promoter mutants that alter the −35 to −10 spacing

1982 • 219 citations

The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor.

1985 • 207 citations

Expression of v-src and chicken c-src in rat cells demonstrates qualitative differences between pp60v-src and pp60c-src

1984 • 194 citations

Local mutagenesis of Rous sarcoma virus: The major sites of tyrosine and serine phosphorylation of p60src are dispensable for transformation

1983 • 189 citations

Genetics of RNA Tumor Viruses

1977 • 185 citations

Low Level of Cellular Protein Phosphorylation by Nontransforming Overproduced p60^c-src

1985 • 176 citations

Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin

1984 • 163 citations

Overexpression of the c-src protein does not induce transformation of NIH 3T3 cells.

1984 • 161 citations

Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src

1983 • 138 citations

Highly specific antibody to Rous sarcoma virus src gene product recognizes a novel population of pp60v-src and pp60c-src molecules.

1985 • 133 citations

The stimulation of pp60v-src kinase activity by vanadate in intact cells accompanies a new phosphorylation state of the enzyme.

1984 • 121 citations

Use of bacterial expression cloning to define the amino acid sequences of antigenic determinants on the G2 glycoprotein of Rift Valley fever virus

1986 • 111 citations

Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60src

1983 • 103 citations

Antibodies to a defined region of pp60src neutralize the tyrosine-specific kinase activity.

1983 • 99 citations

Protein Phosphorylation Mediated by Partially Purified Avian Sarcoma Virus Transforming-gene Product

1980 • 98 citations

Development of Anti-pp60 ^src Serum with Antigen Produced in Escherichia coli

1983 • 75 citations

Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus

1986 • 75 citations

Tyrosine phosphorylation within the amino-terminal domain of pp60c-src molecules associated with polyoma virus middle-sized tumor antigen.

1985 • 73 citations

Increase in the phosphotransferase specific activity of purified Rous sarcoma virus pp60v-src protein after incubation with ATP plus Mg2+.

1983 • 68 citations

Structurally and Functionally Modified Forms of pp60^v-src in Rous Sarcoma Virus-Transformed Cell Lysates

1984 • 68 citations

Tyrosine protein kinases.

1984 • 64 citations

An immunologically active chimaeric protein containing herpes simplex virus type 1 glycoprotein D

1983 • 63 citations

Antiserum specific for the carboxy terminus of the transforming protein of Rous sarcoma virus

1982 • 54 citations

Synthetic peptide fragment of src gene product inhibits the src protein kinase and crossreacts immunologically with avian onc kinases and cellular phosphoproteins.

1981 • 54 citations

Molecular cloning of avian sarcoma virus closed circular DNA: structural and biological characterization of three recombinant clones

1980 • 53 citations

A mutation at the major phosphotyrosine in pp60v-src alters oncogenic potential

1984 • 52 citations

Physical modification of purified rous sarcoma virus pp60v-src protein after incubation with ATP/Mg2+

1983 • 50 citations

Phospholipids stimulate phosphorylation of vinculin by the tyrosine-specific protein kinase of Rous sarcoma virus.

1982 • 43 citations

Detection of the Viral Sarcoma Gene Product in Cells Infected with Various Strains of Avian Sarcoma Virus and of a Related Protein in Uninfected Chicken Cells

1979 • 41 citations

Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein

1986 • 34 citations

Bacterial Synthesis of Herpes Simplex Virus Types 1 and 2 Glycoprotein D Antigens

1984 • 29 citations

Human cells contain two forms of pp60c-src

1981 • 28 citations

Specific proteolytic fragmentation of p60v-src in transformed cell lysates

1983 • 22 citations

Isolation and partial characterization of a monoclonal antibody to the Rous sarcoma virus transforming protein pp60src

1983 • 17 citations

Increase in the Phosphotransferase Specific Activity of Purified Rous Sarcoma Virus pp60^v-src Protein After Incubation with ATP Plus Mg²⁺

1983 • 16 citations

Enzymatic characteristics of pp60^v‐src isolated from vanadium‐treated transformed cells

1984 • 7 citations