The role of interleukin-5 in protective immunity to Strongyloides venezuelensis infection in mice.

Antibody to Interleukin-5 Inhibits Helminth-Induced Eosinophilia in Mice

1989 • 635 citations

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor.

1988 • 619 citations

Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors.

1988 • 528 citations

Eosinophils as mediators of antibody-dependent damage to schistosomula

1975 • 369 citations

Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni.

1990 • 238 citations

Isolation and characterization of lymphokine cDNA clones encoding mouse and human IgA-enhancing factor and eosinophil colony-stimulating factor activities: relationship to interleukin 5.

1987 • 236 citations

Characterization of T helper 1 and 2 cell subsets in normal mice. Helper T cells responsible for IL-4 and IL-5 production are present as precursors that require priming before they develop into lymphokine-secreting cells.

1988 • 172 citations

Murine eosinophil differentiation factor. An eosinophil-specific colony-stimulating factor with activity for human cells.

1986 • 170 citations

Interleukin 5, a T-cell-derived B-cell differentiation factor also induces cytotoxic T lymphocytes.

1987 • 140 citations

Eosinophils and resistance to Trichinella spiralis.

1977 • 134 citations

Regulation of parasite-induced eosinophilia: selectively increased interleukin 5 production in helminth-infected patients.

1990 • 131 citations

Human eosinophil hematopoiesis studied in vitro by means of murine eosinophil differentiation factor (IL5): production of functionally active eosinophils from normal human bone marrow

1988 • 120 citations

Antigen-induced T cell-replacing factor (TRF). I. Functional characterization of a TRF-producing helper T cell subset and genetic studies on TRF production.

1980 • 118 citations

BCGFII activity on activated B cells of a purified murine T cell-replacing factor (TRF) from a T cell hybridoma (B151K12).

1985 • 100 citations

Defective protective capacity of W/W^v mice against Strongyloides vatti infection and its reconstitution with bone marrow cells

1985 • 98 citations

Production of a monoclonal antibody useful in the molecular characterization of murine T-cell-replacing factor/B-cell growth factor II.

1987 • 88 citations

Worm expulsion and mucosal mast cell response induced by repetitive IL-3 administration in Strongyloides ratti-infected nude mice.

1988 • 82 citations

Characterization of the murine interleukin 5 receptor by using a monoclonal antibody

1990 • 53 citations

In vivo changes of hemopoietic progenitors and the expression of the interleukin 5 gene in eosinophilic mice infected with Toxocara canis.

1990 • 41 citations

Strongyloides ratti: Dissociation of the rat's protective immunity into systemic and intestinal components

1981 • 31 citations

Effects of spleen cells and serum on transfer of immunity to Strongyloides venezuelensis infection in hypothymic (nude) mice

1990 • 26 citations

Strongyloides ratti: The role of enteral antigenic stimuli by adult worms in the generation of protective immunity in rats

1983 • 22 citations

Effects of Preintestinal Larval Antigenic Stimuli on the Generation of Intestinal Immunity in Strongyloides ratti Infection in Rats

1983 • 21 citations

STRONGYLOIDES RATTI: INCREASE IN SUSCEPTIBILITY TO INFECTION FOLLOWING BLOCKADE OF THE MONONUCLEAR PHAGOCYTE SYSTEM IN FEMALE MICE

1985 • 16 citations

THE LOCATION OF ANTIGENIC SITES ON THE SURFACE OF THE NEMATODE PARASITE STRONGYLOIDES RATTI REACTIVE TO ANTIBODY‐DIRECTED CELLULAR CYTOTOXICITY FROM BOTH MACROPHAGES AND EOSINOPHILS FROM THE NATURAL HOST

1983 • 10 citations

Effects of Rat and Human Intestinal Lamina Propria Cells on Viability and Muscle Establishment of Trichinella spiralis Newborn Larvae

1989 • 8 citations

Dissociation of the protective immune response in the mouse to Strongyloides ratti

1989 • 6 citations