The structure and biosynthesis of new tetrahydropyrimidine derivatives in actinomycin D producer Streptomyces parvulus. Use of 13C- and 15N-labeled L-glutamate and 13C and 15N NMR spectroscopy.

Mass spectrometry : organic chemical applications

1962 • 641 citations

Control of antibiotic biosynthesis

1980 • 469 citations

Regulation of Secondary Metabolite Biosynthesis: Catabolite Repression of Phenoxazinone Synthase and Actinomycin Formation by Glucose

1972 • 149 citations

Effects of intracellular trehalose content on Streptomyces griseus spores

1987 • 80 citations

Glycogen and Trehalose Accumulation during Colony Development in Streptomyces antibioticus

1986 • 74 citations

Development of a Chemically Defined Medium for the Synthesis of Actinomycin D by Streptomyces parvulus

1977 • 63 citations

13C NMR studies of carbon metabolism in the hyphal fungus Aspergillus nidulans.

1985 • 58 citations

Actinomycin synthetases. Multifunctional enzymes responsible for the synthesis of the peptide chains of actinomycin.

1987 • 57 citations

Partial Purification and Properties of a Highly Specific Trehalose Phosphate Phosphatase from Mycobacterium smegmatis

1971 • 45 citations

The biosynthesis of tabtoxinine-beta-lactam. Use of specifically 13C-labeled glucose and 13C NMR spectroscopy to identify its biosynthetic precursors.

1987 • 43 citations

In vivo 15N NMR studies of regulation of nitrogen assimilation and amino acid production by Brevibacterium lactofermentum.

1983 • 42 citations

Regulation of pool sizes and turnover rates of amino acids in humans: 15N-glycine and 15N-alanine single-dose experiments using gas chromatography—Mass spectrometry analysis

1980 • 33 citations

¹³C‐NMR, ¹H‐NMR and gas‐chromatography mass‐spectrometry studies of the biosynthesis of ¹³C‐enriched <scp>l</scp>‐lysine by Brevibacterium flavum

1987 • 30 citations

Acyl pentapeptide lactone synthesis in actinomycin-producing streptomycetes by feeding with structural analogs of 4-methyl-3-hydroxyanthranilic acid.

1984 • 30 citations

Purification and characterization of kynurenine formamidase activities from Streptomyces parvulus

1986 • 29 citations

Distinct kynureninase and hydroxykynureninase enzymes in an actinomycin-producing strain of Streptomyces parvulus

1980 • 26 citations

Control of Actinomycin D Biosynthesis inStreptomyces parvullus: Regulation of Tryptophan Oxygenase Activity

1981 • 24 citations

A quantitative analysis of the metabolic pathways of hepatic glucose synthesis in vivo with ¹³C‐labeled substrates

1987 • 24 citations

Natural‐abundance ¹³C nuclear magnetic resonance studies of regulation and overproduction of <scp>l</scp>‐lysine by Brevibacterium flavum

1985 • 17 citations

Microbial production of l-[15N]glutamic acid and its gas chromatography-mass spectrometry analysis

1983 • 15 citations