Purified yeast RNA polymerase II reads through intrinsic blocks to elongation in response to the yeast TFIIS analogue, P37.

Transcriptional regulation

1991 • 893 citations

Eukaryotic RNA Polymerase

1985 • 500 citations

Transcript cleavage factors from E. coli

1993 • 368 citations

Tails of RNA polymerase II

1990 • 320 citations

Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II

1987 • 306 citations

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII.

1992 • 280 citations

The C-terminal domain of the largest subunit of RNA polymerase II of Saccharomyces cerevisiae, Drosophila melanogaster, and mammals: a conserved structure with an essential function.

1988 • 246 citations

Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro.

1991 • 241 citations

Transcription elongation and eukaryotic gene regulation.

1990 • 227 citations

Elongation factor-dependent transcript shortening by template-engaged RNA polymerase II.

1992 • 197 citations

Studies of in vitro transcription by calf thymus RNA polymerase II using a novel duplex DNA template.

1982 • 193 citations

Transcription Elongation Factor SII (TFIIS) Enables RNA Polymerase II to Elongate through a Block to Transcription in a Human Gene in Vitro

1989 • 189 citations

RNA Polymerase II Subunit RPB4 Is Essential for High- and Low-Temperature Yeast Cell Growth

1989 • 173 citations

Purification of eukaryotic RNA polymerase II by immunoaffinity chromatography. Elution of active enzyme with protein stabilizing agents from a polyol-responsive monoclonal antibody.

1990 • 163 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Transcription factor IIS stimulates elongation of RNA chains.

1987 • 160 citations

Structural analysis of ternary complexes of Escherichia coli RNA polymerase

1992 • 154 citations

Role of the mammalian transcription factors IIF, IIS, and IIX during elongation by RNA polymerase II.

1991 • 152 citations

Spontaneous cleavage of RNA in ternary complexes of Escherichia coli RNA polymerase and its significance for the mechanism of transcription.

1991 • 149 citations

GreA protein: a transcription elongation factor from Escherichia coli.

1992 • 149 citations

Genetic Interaction between Transcription Elongation Factor TFIIS and RNA Polymerase II

1992 • 136 citations

RNA polymerase II subunit composition, stoichiometry, and phosphorylation.

1990 • 127 citations

RNA polymerase: regulation of transcript elongation and termination

1991 • 127 citations

Purification and lipid-layer crystallization of yeast RNA polymerase II.

1990 • 113 citations

Analysis of the signals for transcription termination by purified RNA polymerase II

1990 • 113 citations

Fifty years of amanitin

1991 • 109 citations

The increment of SII-facilitated transcript cleavage varies dramatically between elongation competent and incompetent RNA polymerase II ternary complexes

1993 • 106 citations

Elongation factor SII-dependent transcription by RNA polymerase II through a sequence-specific DNA-binding protein.

1993 • 104 citations

Specific interaction of the murine transcription termination factor TTF I with class-I RNA polymerases

1990 • 104 citations

Identification of a 3'-->5' exonuclease activity associated with human RNA polymerase II.

1993 • 103 citations

Identification of intrinsic termination sites in vitro for RNA polymerase II within eukaryotic gene sequences

1987 • 97 citations

Purification and functional characterization of transcription factor SII from calf thymus. Role in RNA polymerase II elongation.

1987 • 96 citations

Identification of rpo30, a vaccinia virus RNA polymerase gene with structural similarity to a eucaryotic transcription elongation factor.

1990 • 96 citations

The RNA polymerase II elongation complex. Factor-dependent transcription elongation involves nascent RNA cleavage.

1992 • 92 citations

RNA polymerase II: subunit structure and function

1990 • 92 citations

Purification and preparation of antibody to RNA polymerase II stimulatory factors from Ehrlich ascites tumor cells

1979 • 86 citations

Stimulation of transcript elongation requires both the zinc finger and RNA polymerase II binding domains of human TFIIS

1991 • 86 citations

SII-facilitated transcript cleavage in RNA polymerase II complexes stalled early after initiation occurs in primarily dinucleotide increments

1993 • 83 citations

RPB7, one of two dissociable subunits of yeast RNA polymerase II, is essential for cell viability

1993 • 82 citations

Purification, gene cloning, and gene disruption of the transcription elongation factor S-II in Saccharomyces cerevisiae.

1992 • 80 citations

Nascent RNA cleavage by arrested RNA polymerase II does not require upstream translocation of the elongation complex on DNA.

1993 • 80 citations

Molecular cloning and characterization of cDNA for eukaryotic transcription factor S-II.

1988 • 76 citations

Purified elongation factor SII is sufficient to promote read-through by purified RNA polymerase II at specific termination sites in the human histone H3.3 gene.

1990 • 75 citations

RNA Polymerase Marching Backward

1993 • 74 citations

Properties of a Drosophila RNA Polymerase II Elongation Factor

1989 • 73 citations

3'-end formation of mouse pre-rRNA involves both transcription termination and a specific processing reaction.

1989 • 70 citations

Analysis of the stimulatory factor of RNA polymerase II in the initiation and elongation complex.

1984 • 69 citations

Interaction of a new polypeptide with yeast RNA polymerase B.

1980 • 68 citations

Complete sequence of a eukaryotic regulatory gene.

1983 • 63 citations

Structure of RNA and DNA chains in paused transcription complexes containing Escherichia coli RNA polymerase

1992 • 62 citations

Nascent RNA cleavage by purified ternary complexes of vaccinia RNA polymerase.

1993 • 62 citations

Mechanism of DmS-II-mediated pause suppression by Drosophila RNA polymerase II.

1993 • 58 citations

Cloning, expression and characterization of the human transcription elongation factor, TFIIS

1991 • 54 citations

Mechanistic studies of transcription arrest at the adenovirus major late attenuation site. Comparison of purified RNA polymerase II and washed elongation complexes.

1992 • 54 citations

Contacts between mammalian RNA polymerase II and the template DNA in a ternary elongation complex

1993 • 49 citations

RNA Polymerase II Elongation Complexes Paused after the Synthesis of 15- or 35-Base Transcripts Have Different Structures

1991 • 45 citations

Stimulatory proteins of RNA polymerase II from Ehrlich ascites tumor cells

1982 • 42 citations

Drosophila RNA polymerase II elongation factor DmS-II has homology to mouse S-II and sequence similarity to yeast PPR2

1990 • 42 citations

Heterogeneity and Tissue-Specific Expression of Eukaryotic Transcription Factor S-II-Related Protein mRNA1

1991 • 33 citations

Structural relationships of the three stimulatory factors of RNA polymerase II from Ehrlich ascites tumor cells.

1985 • 30 citations

Transcription elongation factor SII interacts with a domain of the large subunit of human RNA polymerase II.

1988 • 30 citations

Characterization of a HeLa cDNA clone encoding the human SII protein, an elongation factor for RNA polymerase II

1992 • 25 citations

Native deoxyribonucleic acid transcription by yeast RNA polymerase-P37 complex

1981 • 18 citations

Similar binding site for P37 factor on yeast RNA polymerases A and B

1980 • 17 citations

Site-directed mutagenesis of arginine 246, glutamic acid 247, and histidine 248 in the eukaryotic transcription factor S-II.

1990 • 7 citations