Murine Bone Marrow-Derived Mast Cells as Potent Producers of IL-9: Costimulatory Function of IL-10 andkitLigand in the Presence of IL-1

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

1990 • 1,155 citations

Luciferase reporter gene vectors for analysis of promoters and enhancers.

1988 • 1,016 citations

Mast cells as a source of multifunctional cytokines

1990 • 708 citations

Interleukin 10: a novel stimulatory factor for mast cells and their progenitors.

1991 • 514 citations

Expression of Interleukin 9 in the Lungs of Transgenic Mice Causes Airway Inflammation, Mast Cell Hyperplasia, and Bronchial Hyperresponsiveness

1998 • 448 citations

Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities.

1984 • 386 citations

Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis.

1995 • 354 citations

Cytokine production by mast cells and basophils

1991 • 344 citations

Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors.

1990 • 304 citations

Mast cell growth‐enhancing activity (MEA) is structurally related and functionally identical to the novel mouse T cell growth factor P40/TCGFIII (interleukin 9)

1990 • 302 citations

PCR Technology

1989 • 297 citations

IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma.

1994 • 284 citations

Interleukin 9: A candidate gene for asthma

1997 • 236 citations

Evidence for Linkage Between Asthma/Atopy in Childhood and Chromosome 5q31-q33 in a Japanese Population

1997 • 187 citations

Interleukin‐9 is involved in host protective immunity to intestinal nematode infection

1997 • 185 citations

Generation of hybridomas secreting murine reaginic antibodies of anti-DNP specificity.

1980 • 176 citations

Cloning and characterization of a cDNA for a new mouse T cell growth factor (P40).

1989 • 173 citations

The mast cell in health and disease

1990 • 170 citations

Interleukin-9 Enhances Resistance to the Intestinal NematodeTrichuris muris

1998 • 149 citations

Intraepithelial Infiltration by Mast Cells with Both Connective Tissue-Type and Mucosal-Type Characteristics in Gut, Trachea, and Kidneys of IL-9 Transgenic Mice

1998 • 137 citations

IL-9 induces chemokine expression in lung epithelial cells and baseline airway eosinophilia in transgenic mice

1999 • 135 citations

Interleukin 9 and its Receptor: An Overview of Structure and Function

1998 • 129 citations

Tcgfiii/p40 is produced by naive murine cd4+ t cells but is not a general t cell growth factor*

1989 • 115 citations

IL-9 pathway in asthma: New therapeutic targets for allergic inflammatory disorders

1999 • 115 citations

A comparison of apparent mRNA half-life using kinetic labeling techniques vs decay following administration of transcriptional inhibitors

1991 • 114 citations

Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene.

1990 • 109 citations

Thiol-sensitive mast cell lines derived from mouse bone marrow respond to a mast cell growth-enhancing activity different from both IL-3 and IL-4.

1989 • 93 citations

The cromolyn binding protein constitutes the Ca2+ channel of basophils opening upon immunological stimulus.

1984 • 92 citations

Interleukin 9 is expressed by primary and cultured Hodgkin and Reed-Sternberg cells.

1992 • 89 citations

Differential regulation of mast cell function by IL-10 and stem cell factor.

1997 • 76 citations

Potential role of interleukin-1 in allergen-induced late asthmatic reactions in guinea pigs: Suppressive effect of interleukin-1 receptor antagonist on late asthmatic reaction

1995 • 74 citations

IL-1 serves as a secondary signal for IL-9 expression.

1991 • 71 citations

A cascade of cytokines is responsible for IL-9 expression in human T cells. Involvement of IL-2, IL-4, and IL-10.

1995 • 61 citations

IL-4-independent regulation of in vivo IL-9 expression.

1997 • 57 citations

Co-activation of naive CD4⁺ T cells and bone marrow-derived mast cells results in the development of T_h2 cells

1995 • 55 citations

Stem Cell Factor-Induced Airway Hyperreactivity in Allergic and Normal Mice

1999 • 54 citations

Interleukin‐9 stimulates in vitro growth of mouse thymic lymphomas

1993 • 47 citations

Characterization of hemopoietic cell populations from human cord blood expressing c-kit.

1993 • 47 citations

Airway epithelial cells produce stem cell factor

1996 • 44 citations

Partial purification of a mast cell growth-enhancing activity and its separation from IL-3 and IL-4.

1989 • 37 citations

Characterization of a T-cell-derived mast cell costimulatory activity (MCA) that acts synergistically with interleukin 3 and interleukin 4 on the growth of murine mast cells

1990 • 9 citations

mRNA Abundance and Half-Life Measurements

2003 • 4 citations