Diabetic and Galactosaemic Cataracts

Formation of Polyols by the Lens of the Rat with ‘Sugar’ Cataract

1959 • 431 citations

Polyol Accumulation in Galactosemic and Diabetic Rats: Control by an Aldose Reductase Inhibitor

1973 • 262 citations

Diabetic Cataracts and Flavonoids

1977 • 189 citations

The sorbitol pathway in the human lens: aldose reductase and polyol dehydrogenase.

1981 • 161 citations

Immunohistochemical Localization of Aldose Reductase: II. Rat Eye and Kidney

1980 • 148 citations

Sorbitol pathway in diabetic and galactosemic rat lens

1974 • 130 citations

Role of nonenzymatic glycosylation in the development of the sequelae of diabetes mellitus

1979 • 116 citations

A biochemical evaluation of a cataract induced in a high-glucose medium.

1969 • 112 citations

Altering the course of cataracts in diabetic rats.

1980 • 108 citations

Implications of aldose reductase in cataracts in human diabetes.

1979 • 106 citations

The absence of cataracts in mice with congenital hyperglycemia

1974 • 95 citations

The Effect of an Aldose Reductase Inhibitor (Sorbinil) on the Level of Metabolites in Lenses of Diabetic Rats

1983 • 95 citations

Disulphide cross-linked protein of high molecular weight in human cataractous lens

1973 • 92 citations

Cortical cataract formation prevented by vitamin E and glutathione

1979 • 81 citations

Galactose cataract prevention with sorbinil, an aldose reductase inhibitor: a light microscopic study.

1982 • 80 citations

Glucosylation of human lens protein and cataractogenesis

1979 • 78 citations

Biochemical changes associated with the development and reversal of galactose cataracts

1976 • 75 citations

Affinity purification and glucose specificity of aldose reductase from bovine lens

1982 • 72 citations

Role of nonenzymatic glycosylation in experimental cataract formation

1980 • 68 citations

Galactokinase Deficiency as a Cause of Cataracts

1973 • 64 citations

Changes in cation permeability in the galactose-exposed rabbit lens

1968 • 60 citations

Role of glycosylation in protein disulfide formation and cataractogenesis

1980 • 59 citations

Presenile Cataract Formation and Decreased Activity of Galactosemic Enzymes

1980 • 56 citations

The oxidation of oxyhaemoglobin by glyceraldehyde and other simple monosaccharides

1984 • 56 citations

The effects of xylose on the isolated lens.

1974 • 52 citations

Galactokinase Deficiency and Cataracts

1972 • 49 citations

Efficacy of Alrestatin, An Aldose Reductase Inhibitor, in Human Diabetic and Nondiabetic Lenses

1979 • 46 citations

Bovine lens aldehyde reductase (aldose reductase). Purification, kinetics and mechanism

1984 • 46 citations

Studies on free and enzyme-bound nicotinamide adenine dinucleotide free radicals

1980 • 43 citations

Alterations of lens protein synthesis in galactosemic rats.

1979 • 42 citations

The effect of an unsaturated-fat diet on cataract formation in streptozotocin-induced diabetic rats

1976 • 40 citations

Aldose reductase and sorbitol dehydrogenase distribution in substructures of normal and diabetic rat lens.

1977 • 38 citations

Diminished sugar cataractogenesis by quercetin

1979 • 31 citations

Reversible Unilateral Lens Opacities in a Diabetic Patient

1976 • 28 citations

The Nutritional Teamwork Approach: Prevention and Regression of Cataracts in Rats

1974 • 25 citations

Inhibition of Sorbitol Production in Human Lenses by an Aldose Reductase Inhibitor

1979 • 23 citations

13C-nuclear magnetic resonance studies of sugar cataractogenesis in the single intact rabbit lens.

1982 • 21 citations

NADPH-oxidising activity in lens and erythrocytes in diabetic and nondiabetic patients with cataract.

1983 • 19 citations

Effect of gossypin, a flavonoid, on the formation of galactose-induced cataracts in rats

1979 • 16 citations

Some effects of aldose reductase inhibition upon the eyes of long-term streptozotocin-diabetic rats

1982 • 13 citations

Galactokinase-Deficiency Cataracts in Identical Twins

1972 • 10 citations

Topical Treatment of Galactose Cataracts

1976 • 9 citations

Xylose cataract: A comparison between the weanling and the older rat

1969 • 8 citations

[Effects of M79175, an aldose reductase inhibitor, on experimental sugar cataracts].

1982 • 6 citations

Optical spectroscopy as an in vitro method to monitor aldose reductase inhibitors in the lens.

1983 • 5 citations

Localization of aldose reductase in the human eye

1984 • 1 citations