Gonadal hormones affect neuronal vulnerability to excitotoxin-induced degeneration.

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

1996 • 1,640 citations

Unbiased Stereology: Three-Dimensional Measurement in Microscopy

1998 • 1,154 citations

The Endocrinology of Aging

1997 • 957 citations

Estrogen Deficiency and Risk of Alzheimer's Disease in Women

1994 • 843 citations

Organizational and activational effects of sex steroids on brain and behavior: A reanalysis

1985 • 811 citations

Kainic acid seizures in the rat

1994 • 693 citations

17-β Estradiol Protects Neurons from Oxidative Stress-Induced Cell Death in Vitro

1995 • 612 citations

The Mitogen-Activated Protein Kinase Pathway Mediates Estrogen Neuroprotection after Glutamate Toxicity in Primary Cortical Neurons

1999 • 581 citations

Estradiol Protects against Ischemic Injury

1998 • 548 citations

Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate‐treated rats

1997 • 501 citations

Ovarian steroids and the brain

1997 • 481 citations

Estrogen-Induced Activation of Mitogen-Activated Protein Kinase in Cerebral Cortical Explants: Convergence of Estrogen and Neurotrophin Signaling Pathways

1999 • 474 citations

Androgens Prevent Normally Occurring Cell Death in a Sexually Dimorphic Spinal Nucleus

1985 • 470 citations

Novel Mechanisms of Estrogen Action in the Brain: New Players in an Old Story

1999 • 434 citations

Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain.

1992 • 431 citations

The effect of ovariectomy and estradiol replacement on brain-derived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats.

1995 • 422 citations

Aromatase expression by astrocytes after brain injury: implications for local estrogen formation in brain repair

1999 • 366 citations

Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neurons

1994 • 362 citations

Estrogen protects primary cortical neurons from glutamate toxicity

1996 • 329 citations

The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area

1996 • 321 citations

Progesterone Facilitates Cognitive Recovery and Reduces Secondary Neuronal Loss Caused by Cortical Contusion Injury in Male Rats

1994 • 319 citations

17β-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors

1997 • 278 citations

BDNF Mediates the Effects of Testosterone on the Survival of New Neurons in an Adult Brain

1999 • 267 citations

Estrogen and the developing mammalian brain

1999 • 263 citations

Gonadal hormones as promoters of structural synaptic plasticity: Cellular mechanisms

1994 • 263 citations

Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death

1998 • 242 citations

Increased Synaptic Sprouting in Response to Estrogen via an Apolipoprotein E-Dependent Mechanism: Implications for Alzheimer’s Disease

1998 • 241 citations

Progesterone therapy in women with complex partial and secondary generalized seizures

1995 • 216 citations

Stress induces neuronal death in the hippocampus of castrated rats

1992 • 206 citations

The neurosteroid 3α,5α-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy

1995 • 194 citations

Sexual dimorphism and the influence of neonatal androgen in the dorsolateral motor nucleus of the rat lumbar spinal cord

1982 • 178 citations

Brain aromatization of androgens.

1994 • 167 citations

Estrogen Provides Neuroprotection in Transient Forebrain Ischemia Through Perfusion-Independent Mechanisms in Rats

1999 • 166 citations

Analysis of cell death in the trochlear nucleus of the chick embryo: Calibration of the optical disector counting method reveals systematic bias

1999 • 155 citations

Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroid effects by interactions with growth factors?

1988 • 148 citations

Testosterone differentially regulates the regenerative properties of injured hamster facial motoneurons

1991 • 128 citations

β-Estradiol protects hippocampal CA1 neurons against transient forebrain ischemia in gerbil

1997 • 126 citations

Estradiol prevents kainic acid-induced neuronal loss in the rat dentate gyrus

1998 • 117 citations

Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation

1996 • 117 citations

Trophic Effects of Estradiol on Fetal Rat Hypothalamic Neurons

1992 • 104 citations

Estrogen receptor immunoreactivity in the adult primate brain: Neuronal distribution and association with p75,trkA, and choline acetyltransferase

1999 • 94 citations

Gonadal Steroid Regulation of Hamster Facial Nerve Regeneration: Effects of Dihydrotestosterone and Estradiol

1997 • 92 citations

Effect of testosterone on the regeneration of the hypoglossal nerve in rats

1982 • 87 citations

The effects of 17β-estradiol on ischemia-induced neuronal damage in the gerbil hippocampus

1998 • 87 citations

Psychoneuroendocrine Aspects of Temporolimbic Epilepsy

1999 • 86 citations

Androgen Enhances Neuronal Degeneration in the Developing Preoptic Area: Apoptosis in the Anteroventral Periventricular Nucleus (AVPvN-POA)

1994 • 83 citations

Neuronal death in the developing sexually dimorphic periventricular nucleus of the preoptic area in the female rat: Effect of neonatal androgen treatment

1989 • 80 citations

Estrogen and NGF synergistically protect terminally differentiated, ERα-transfected PC12 cells from apoptosis

1999 • 80 citations

Androgen treatment of neonatal rats decreases susceptibility of cerebellar granule neurons to oxidative stress in vitro

1999 • 79 citations

Testosterone propionate administration prevents the loss of neurons within the central part of the medial peroptic nucleus

1993 • 78 citations

Estradiol replacement to female rats facilitates dorsal hippocampal but not ventral hippocampal kindled seizure acquisition

1991 • 76 citations

Cyclic Withdrawal From Endogenous and Exogenous Progesterone Increases Kainic Acid and Perforant Pathway Induced Seizures

1999 • 74 citations

Phasic synaptic remodeling of the rat arcuate nucleus during the estrous cycle depends on insulin-like growth factor-I receptor activation

1999 • 72 citations

Steroid hormone effects on picrotoxin-induced seizures in female and male rats

1989 • 68 citations

Hormonal Effects on Epilepsy in Women

1998 • 68 citations

Psychoneuroendocrine Aspects of Temporolimbic Epilepsy

1999 • 65 citations

Estrogen blocks neurotoxic effects of β-amyloid (1–42) and induces neurite extension on B103 cells

1997 • 62 citations

17 β-Estradiol Attenuates Fimbrial Lesion-Induced Decline of ChAT-Immunoreactive Neurons in the Rat Medial Septum

1997 • 58 citations

Hormonal control of neuron number in sexually dimorphic spinal nuclei of the rat: III. Differential effects of the androgen dihydrotestosterone

1989 • 52 citations

Estradiol replacement facilitates the acquisition of seizures kindled from the anterior neocortex in female rats

1989 • 51 citations

Trophic Effects of Androgen: Receptor Expression and the Survival of Laryngeal Motor Neurons after Axotomy

1996 • 47 citations

The role of neuron death in the development of the gender difference in the number of neurons in the rat superior cervical ganglion

1987 • 41 citations

Androgenic Enhancement of Motor Neuron Regeneration

1994 • 40 citations

Gonadal steroid preservation of central synaptic input to hamster facial motoneurons following peripheral axotomy.

1997 • 40 citations

Action of steroid hormones on growth and differentiation of CNS and spinal cord organotypic cultures

1996 • 16 citations

Mechanism underlying potentiation by progesterone of the kainate-induced current in cultured neurons

1998 • 16 citations