Angiotensin II type I antagonist prevents pulmonary metastasis of murine renal cancer by inhibiting tumor angiogenesis.

Renal-Cell Carcinoma

1996 • 2,232 citations

Transforming growth factor-beta: Vasculogenesis, angiogenesis, and vessel wall integrity

1997 • 715 citations

Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer?

1998 • 551 citations

Antibody to transforming growth factor-β ameliorates tubular apoptosis in unilateral ureteral obstruction

2000 • 322 citations

Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).

1993 • 211 citations

Angiotensin II stimulates angiogenesis in the chorio-allantoic membrane of the chick embryo

1991 • 184 citations

Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist

2001 • 145 citations

Evidence for a novel angiotensin II receptor involved in angiogenesis in chick embryo chorioallantoic membrane

1993 • 128 citations

Angiotensin II in renal fibrosis: should TGF-beta rather than blood pressure be the therapeutic target?

1997 • 122 citations

Differences between Squamous Cell Carcinoma and Keratoacanthoma in Angiotensin Type-1 Receptor Expression

2001 • 85 citations

Angiotensin II receptors: protein and gene structures, expression and potential pathological involvements

1996 • 85 citations

Angiotensin II Receptor Subtypes in the Human Renal Cortex and Renal Cell Carcinoma

1994 • 82 citations

SURGERY OF RENAL CELL CARCINOMA

1993 • 71 citations

Antihypertensive effects of a highly potent and long-acting angiotensin II subtype-1 receptor antagonist, (+-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H- benzimidazole-7-carboxylate (TCV-116), in various hypertensive rats.

1994 • 70 citations

Candesartan cilexetil: a review of its preclinical pharmacology.

1997 • 55 citations

The Role of Angiotensin Receptors in Cardiovascular Diseases

1997 • 50 citations

The effect of high-dose angiotensin II receptor blockade beyond maximal recommended doses in reducing urinary protein excretion

2001 • 41 citations

Recognition of Tissue- and Subtype-Specific Modulation of Angiotensin II Receptors Using Antibodies agains AT1 and AT2 Receptors.

1997 • 36 citations

Candesartan cilexetil: a new, long-acting, effective angiotensin II type 1 receptor blocker.

1997 • 36 citations

Pharmacology of a potent long-acting imidazole-5-acrylic acid angiotensin AT1 receptor antagonist

1995 • 20 citations

Discussion

1999 • 11 citations

Immunostimulatory Therapy With Anti-CD3 Monoclonal Antibodies and Recombinant Interleukin-2: Heightened In Vivo Expression of mRNA Encoding Cytotoxic Attack Molecules and Immunoregulatory Cytokines and Regression of Murine Renal Cell Carcinoma

1997 • 7 citations