The Mechanism of Enzyme-catalyzed Reduced Nicotinamide Adenine Dinucleotide-dependent Reductions

A Reëxamination of the Hammett Equation.

1953 • 2,102 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

1963 • 2,095 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 1,885 citations

Electrophilic Substituent Constants

1958 • 1,101 citations

The Magnitude of the Primary Kinetic Isotope Effect for Compounds of Hydrogen and Deuterium.

1961 • 740 citations

CRYSTALLINE ALCOHOL DEHYDROGENASE FROM BAKERS' YEAST

1950 • 630 citations

Molecular complexes;: A lecture and reprint volume

1969 • 396 citations

The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinase

1966 • 196 citations

The Oxidation Potentials of Aldehydes and Ketones

1949 • 164 citations

Equilibria for additions to the carbonyl group

1968 • 162 citations

The Reduction of Thioketones by a Model for a Coenzyme

1957 • 148 citations

Equilibrium Reaction Rates and the Mechanisms of Liver and Yeast Alcohol Dehydrogenase

1964 • 110 citations

Reactions of dihydronicotinamides. I. Evidence for an intermediate in the reduction of trifluoroacetophenone by 1-substituted dihydronicotinamides

1971 • 104 citations

The Calculation of an Enzyme-Substrate Dissociation Constant from the Over-all Initial Velocity for Reactions Involving Two Substrates

1957 • 93 citations

Mechanisms of Enzyme-catalyzed Oxidation-Reduction Reactions. I. An Investigation of the Yeast Alcohol Dehydrogenase Reaction by Means of the Isotope Rate Effect^1,2

1957 • 91 citations

Kinetic Studies with Liver Alcohol Dehydrogenase^*

1965 • 80 citations

[127] Enzymatic preparation of DPNH and TPNH

1957 • 74 citations

Model for alcohol dehydrogenase. Zinc ion catalyzed reduction of 1,10-phenanthroline-2-carboxyaldehyde by N-propyl-1,4-dihydronicotinamide

1971 • 73 citations

Correlation of kinetic isotope effects with chemical bonding in three-centre reactions

1964 • 60 citations

Effect of substrate structure on the rate of the catalytic step in the liver alcohol dehydrogenase mechanism

1971 • 57 citations

Primary kinetic isotope effects and nature of hydrogen-transfer transition states. Reaction of a series of free radicals with thiols

1971 • 57 citations

Pyridinium Complexes. IV. The Effect of N-Substituents on the Position of the Iodide Charge-transfer Band

1962 • 55 citations

Use of Substituent Effects on Isotope Effects to Distinguish between Proton and Hydride Transfers. Part I. Mechanism of Oxidation of Alcohols by Bromine in Water^1-3

1961 • 52 citations

Rate constants for reaction of hydrogen atoms with aromatic and heterocyclic compounds. Electrophilic nature of hydrogen atoms

1972 • 38 citations

The Effect of o-Substituents on Benzaldehyde Semicarbazone Formation¹

1961 • 35 citations

The Structure of a New Product from Yeast: 2-(6-Hydroxy-2-methoxy-3,4-methylenedioxyphenyl)-benzofuran

1959 • 25 citations

Evidence for Parallel Control of Reaction Rate and Stereochemistry via the Electrostatic Influence of Remote Substituent Dipoles

1962 • 24 citations

A systematic examination of charge transfer interactions of a coenzyme model

1965 • 24 citations

Stable free radicals. V. Reaction between 1-ethyl-4-carbomethoxypyridinyl and benzyl halides

1971 • 23 citations

Electronic Effects in Horse Liver Alcohol Dehydrogenase Catalysis.

1966 • 23 citations

Electronic, hydrophobic, and steric effects of binding of inhibitors to the horse liver alcohol dehydrogenase-reduced pyridine coenzyme binary complex

1972 • 21 citations

Deuterium Effects on Binding of Reduced Coenzyme Alcohol Dehydrogenase Isoenzyme EE

1971 • 20 citations

The Effect of Substitution on the Solvolysis Rates of Benzhydryl Chlorides¹

1952 • 7 citations