Expression of the alpha7beta1 laminin receptor suppresses melanoma growth and metastatic potential.

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

1997 • 1,400 citations

Integrins and anoikis

1997 • 1,145 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

The tetraspanin superfamily: molecular facilitators

1997 • 938 citations

Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.

1987 • 727 citations

Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations.

1991 • 447 citations

Anchorage-dependent Cell Cycle Progression

1997 • 384 citations

Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown.

1993 • 335 citations

The α6β4 Integrin Is a Receptor for both Laminin and Kalinin

1994 • 315 citations

Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).

1996 • 274 citations

H36-alpha 7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis [published erratum appears in J Cell Biol 1992 Jul;118(1):213]

1992 • 236 citations

Association of TM4SF proteins with integrins: relevance to cancer

1996 • 209 citations

Activation of β1 Integrin Signaling Stimulates Tyrosine Phosphorylation of p190 and Membrane-protrusive Activities at Invadopodia

1998 • 204 citations

Demonstration of multiple phenotypic diversity in a murine melanoma of recent origin.

1981 • 195 citations

Inhibition of the Mitogen-activated Protein Kinase Pathway Triggers B16 Melanoma Cell Differentiation

1998 • 187 citations

Laminin 5 Deposition Promotes Keratinocyte Motility

1996 • 185 citations

Specific Association Of CD63 with the VLA-3 and VLA-6 Integrins

1995 • 181 citations

β1 And β3 integrins have different roles in the adhesion and migration of vascular smooth muscle cells on extracellular matrix

1992 • 179 citations

Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production.

1990 • 178 citations

Identification of integrin α3β1 as a neuronal thrombospondin receptor mediating neurite outgrowth

1995 • 166 citations

Characterization of the enhanced adhesion of neutrophil leukocytes to thrombin-stimulated endothelial cells.

1990 • 163 citations

Skeletal myoblasts utilize a novel beta 1-series integrin and not alpha 6 beta 1 for binding to the E8 and T8 fragments of laminin.

1991 • 158 citations

A new isoform of the laminin receptor integrin alpha 7 beta 1 is developmentally regulated in skeletal muscle.

1993 • 150 citations

Alternative extracellular and cytoplasmic domains of the integrin alpha 7 subunit are differentially expressed during development.

1993 • 150 citations

CD9-regulated adhesion. Anti-CD9 monoclonal antibody induce pre-B cell adhesion to bone marrow fibroblasts through de novo recognition of fibronectin.

1994 • 136 citations

Identification and Characterization of the Cell Type-specific and Developmentally Regulated α7 Integrin Gene Promoter

1996 • 132 citations

Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor

1996 • 124 citations

The α3β1 Integrin Is Involved in Melanoma Cell Migration and Invasion

1995 • 120 citations

Human melanoma cells express a novel integrin receptor for laminin

1989 • 120 citations

A Mechanism for Regulation of Melanoma Invasion

1996 • 117 citations

α7 Integrin Mediates Cell Adhesion and Migration on Specific Laminin Isoforms

1996 • 116 citations

Cell and heparin binding in the distal long arm of laminin: identification of active and cryptic sites with recombinant and hybrid glycoprotein [published erratum appears in J Cell Biol 1993 Dec;123(6 Pt 1):1623]

1993 • 110 citations

Formation of hemidesmosomes in cells of a transformed murine mammary tumor cell line and mechanisms involved in adherence of these cells to laminin and kalinin

1993 • 105 citations

Identification of a Melanoma Progression Antigen as Integrin VLA-2

1991 • 89 citations

Specific Induction of Cell Motility on Laminin by α7 Integrin

1996 • 81 citations

Integrin expression in malignant melanoma

1991 • 77 citations

Suppression of mouse melanoma metastasis by EA-1, a monoclonal antibody specific for alpha 6 integrins.

1993 • 73 citations

The Role of Integrins in Tumorigenesis and Metastasis

1998 • 71 citations

Regulation of integrin‐mediated adhesion to laminin and collagen in human melanocytes and in non‐metastatic and highly metastatic human melanoma cells

1993 • 70 citations

Laminin-binding integrins in tumor progression and metastasis

1996 • 65 citations

Liver metastasis formation by laminin-1 peptide (LQVQLSIR)-adhesion selected B16-F10 melanoma cells

1997 • 58 citations

Glomerular epithelial and mesangial cells differentially modulate the binding specificities of VLA-1 and VLA-2.

1995 • 58 citations

Different Deficiencies in the Prevention of Tumorigenic-Low-Metastatic Murine K-1735b Melanoma Cells From Producing Metastases<xref ref-type="fn" rid="FN2">2</xref>

1986 • 54 citations

The laminin-binding activity of the alpha 7 integrin receptor is defined by developmentally regulated splicing in the extracellular domain.

1997 • 48 citations

Modulation of murine B16F10 melanoma plasminogen activator production by a synthetic peptide derived from the laminin A chain.

1993 • 47 citations

Melanoma cells selected for adhesion to laminin peptides have different malignant properties.

1993 • 40 citations

Role of Integrin α2β1 (VLA-2) in the Migration of Human Melanoma Cells on Laminin and Type IV Collagen

1993 • 37 citations

Thein vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants

1989 • 37 citations

Mitogenic activity of laminin on human melanoma and melanocytes: different signal requirements and role of beta 1 integrins.

1995 • 35 citations

Integrin β3 cDNA Transfection into a Highly Metastatic αvβ3-Negative Human Melanoma Cell Line Inhibits Invasion and Experimental Metastasis

1996 • 33 citations

Predominance of the metastatic phenotype in somatic cell hybrids of the K-1735 murine melanoma.

1991 • 23 citations

Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras.

1989 • 23 citations

Studies on the effects of laminin, E-8 fragment of laminin and synthetic laminin peptides PA22-2 and YIGSR on matrix metalloproteinases and tissue inhibitor of metalloproteinase expression.

1994 • 20 citations

Expression of the Human α2 Integrin Subunit in Mouse Melanoma Cells Confers the Ability to Undergo Collagen-Directed Adhesion, Migration, and Matrix Reorganization

1996 • 17 citations

Correlation of melanoma cell motility and invasion in vitro

1995 • 11 citations