The Cell and Molecular Biology of Apolipoprotein E Synthesis by Macro Phages

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

1983 • 1,918 citations

Regulation of Plasma Cholesterol by Lipoprotein Receptors

1981 • 958 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Secretory products of macrophages and their physiological functions

1984 • 494 citations

Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells

1982 • 340 citations

Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E.

1981 • 302 citations

Biochemical and genetic studies of the apoprotein E secreted by mouse macrophages and human monocytes.

1982 • 296 citations

Independent Pathways for Secretion of Cholesterol and Apolipoprotein E by Macrophages

1983 • 162 citations

Rat apolipoprotein E mRNA. Cloning and sequencing of double-stranded cDNA.

1983 • 137 citations

Cellular and molecular biology of lymphokines

1985 • 124 citations

Apoprotein E suppresses phytohemagglutinin-activated phospholipid turnover in peripheral blood mononuclear cells.

1982 • 107 citations

How the macrophage regulates its extracellular environment

1983 • 102 citations

Endotoxin suppresses expression of apoprotein E by mouse macrophages in vivo and in culture. A biochemical and genetic study.

1983 • 86 citations

Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages.

1983 • 80 citations

Onset of apoprotein E secretion during differentiation of mouse bone marrow-derived mononuclear phagocytes.

1983 • 79 citations

Retroendocytosis of low density lipoprotein. Effect of lysosomal inhibitors on the release of undegraded 125I-low density lipoprotein of altered composition from skin fibroblasts in culture.

1984 • 72 citations

Molecular regulation of MHC class III (C4 and factor B) gene expression in mouse peritoneal macrophages.

1984 • 54 citations

Immunoregulatory plasma low density lipoprotein: the biologic activity and receptor-binding specificity is independent of neutral lipids.

1981 • 38 citations

Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages.

1984 • 36 citations

Imbalanced accumulation of ribosomal RNA in macrophages activated in vivo or in vitro to a cytolytic stage.

1985 • 23 citations