NK Cells Lyse T Regulatory Cells That Expand in Response to an Intracellular Pathogen

N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

2003 • 3,323 citations

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 • 2,516 citations

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

2002 • 1,733 citations

Natural versus adaptive regulatory T cells

2003 • 1,363 citations

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

2005 • 1,246 citations

ULBPs, Novel MHC Class I–Related Molecules, Bind to CMV Glycoprotein UL16 and Stimulate NK Cytotoxicity through the NKG2D Receptor

2001 • 1,190 citations

Reciprocal Activating Interaction between Natural Killer Cells and Dendritic Cells

2002 • 1,027 citations

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells

2007 • 818 citations

TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

2006 • 768 citations

CD4+CD25+ TR Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms

2003 • 748 citations

Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4+CD25+ regulatory T cell proliferation

2005 • 716 citations

Foxp3 occupancy and regulation of key target genes during T-cell stimulation

2007 • 695 citations

The Dynamic Life of Natural Killer Cells

2004 • 565 citations

An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection

2004 • 558 citations

Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1

2006 • 532 citations

Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration.

1995 • 458 citations

CD25+CD4+ Regulatory T Cells from the Peripheral Blood of Asymptomatic HIV-infected Individuals Regulate CD4+ and CD8+ HIV-specific T Cell Immune Responses In Vitro and Are Associated with Favorable Clinical Markers of Disease Status

2004 • 444 citations

Regulatory T Cells Are Expanded in Blood and Disease Sites in Patients with Tuberculosis

2005 • 437 citations

NK cell and DC interactions

2003 • 437 citations

Human CD4⁺CD25⁺Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens

2004 • 436 citations

CD4+CD25+ T Regulatory Cells Suppress NK Cell-Mediated Immunotherapy of Cancer

2006 • 395 citations

Escape of malaria parasites from host immunity requires CD4+CD25+ regulatory T cells

2003 • 366 citations

Upregulation of TGF-β, FOXP3, and CD4+CD25+ Regulatory T Cells Correlates with More Rapid Parasite Growth in Human Malaria Infection

2005 • 364 citations

On guard—activating NK cell receptors

2001 • 350 citations

The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo

2005 • 336 citations

Helicobacter pylori - Specific CD4 ⁺ CD25 ^high Regulatory T Cells Suppress Memory T-Cell Responses to H . pylori in Infected Individuals

2003 • 310 citations

Innate Immune Response to Malaria: Rapid Induction of IFN-γ from Human NK Cells by LivePlasmodium falciparum-Infected Erythrocytes

2002 • 306 citations

The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo

2005 • 295 citations

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

2006 • 290 citations

Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of Mycobacterium tuberculosis

2007 • 273 citations

Cross-Talk between Activated Human NK Cells and CD4+ T Cells via OX40-OX40 Ligand Interactions

2004 • 262 citations

Ligands for natural killer cell receptors: redundancy or specificity

2001 • 246 citations

A role for CD4+CD25+ T cells in regulation of the immune response during human tuberculosis

2006 • 232 citations

NK Cell-Derived IFN-γ Differentially Regulates Innate Resistance and Neutrophil Response in T Cell-Deficient Hosts Infected with Mycobacterium tuberculosis

2006 • 225 citations

Activated, But Not Resting, T Cells Can Be Recognized and Killed by Syngeneic NK Cells

2003 • 207 citations

Host innate and Th1 responses and the bacterial factors that control Mycobacterium tuberculosis infection

2005 • 205 citations

NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection

2007 • 198 citations

Role of NK Cell-Activating Receptors and Their Ligands in the Lysis of Mononuclear Phagocytes Infected with an Intracellular Bacterium

2005 • 198 citations

NK Cells Regulate CD8+ T Cell Effector Function in Response to an Intracellular Pathogen

2004 • 165 citations

The NKp46 Receptor Contributes to NK Cell Lysis of Mononuclear Phagocytes Infected with an Intracellular Bacterium

2002 • 162 citations

Virus-induced dysfunction of CD4+CD25+ T cells in patients with HTLV-I–associated neuroimmunological disease

2005 • 158 citations

The Early IL-4 Response toLeishmania majorand the Resulting Th2 Cell Maturation Steering Progressive Disease in BALB/c Mice Are Subject to the Control of Regulatory CD4+CD25+ T Cells

2002 • 146 citations

Regulatory Cells and Infectious Agents: Détentes Cordiale and Contraire

2004 • 143 citations

Suppression of natural killer cell-mediated bone marrow cell rejection by CD4⁺CD25⁺regulatory T cells

2006 • 138 citations

NKG2D ligands are expressed on stressed human airway epithelial cells

2006 • 132 citations

Cell-surface IL-7 receptor expression facilitates the purification of FOXP3+ regulatory T cells

2006 • 127 citations

Mannose‐capped lipoarabinomannan‐ and prostaglandin E2‐dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection

2008 • 112 citations

Th1 memory: implications for vaccine development

2006 • 104 citations

Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses.

1998 • 81 citations

Lymphokine-Activated Killer Cells Lyse Listeria-Infected Hepatocytes and Produce Elevated Quantities of Interferon-

1996 • 25 citations

Murine γ-Herpesvirus 68 Limits Naturally Occurring CD4+CD25+ T Regulatory Cell Activity following Infection

2006 • 22 citations

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