Nonlinear pharmacokinetics of CPT-11 in rats.

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata^1,2

1966 • 2,159 citations

Noncompartmental Determination of the Steady‐State Volume of Distribution

1979 • 740 citations

Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors.

1987 • 412 citations

Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): correlation with preclinical studies.

1972 • 315 citations

Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse.

1990 • 292 citations

Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogs

1980 • 232 citations

Studies on the Antitumor Activity, Mechanism of Action, and Cell Cycle Effects of Camptothecin

1971 • 213 citations

Antitumor effect of CPT-11, a new derivative of camptothecin, against pleiotropic drug-resistant tumors in vitro and in vivo

1988 • 213 citations

Action of camptothecin on mammalian cells in culture.

1972 • 190 citations

Treatment of malignant melanoma with camptothecin (NSC-100880).

1972 • 158 citations

Lethal activity of camptothecin sodium on human lymphoma cells.

1974 • 54 citations

[Antitumor activity of CPT-11 against rat Walker 256 carcinoma].

1988 • 19 citations

Action of 7-ethylcamptothecin on tumor cells and its disposition in mice.

1987 • 18 citations