A guanine nucleotide-binding protein participates in IgE receptor-mediated activation of endogenous and reconstituted phospholipase A2 in a permeabilized cell system.

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

How is the level of free arachidonic acid controlled in mammalian cells?

1982 • 1,193 citations

Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization.

1980 • 653 citations

A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca ²⁺ -Dependent Protein Kinase

1984 • 618 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

Structure and function of phospholiphase A2

1981 • 478 citations

Phospholipase A2 and its zymogen from porcine pancreas. VI. Histidine at the active site of phospholipase A2

1974 • 465 citations

Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.

1986 • 424 citations

A comparison of the crystal structures of phospholipase A2 from bovine pancreas and Crotalus atrox venom.

1985 • 396 citations

The mechanism of the calcium signal and correlation with histamine release in 2H3 cells.

1984 • 351 citations

Stimulation of phospholipase A2 activity in bovine rod outer segments by the beta gamma subunits of transducin and its inhibition by the alpha subunit.

1987 • 344 citations

Calmodulin stimulates human platelet phospholipase A2

1979 • 309 citations

THE INTERACTION OF IgE WITH RAT BASOPHILIC LEUKEMIA CELLS

1974 • 307 citations

Phospholipase A2 and phospholipase C activities of platelets. Differential substrate specificity, Ca2+ requirement, pH dependence, and cellular localization.

1980 • 287 citations

Homology of the rat basophilic leukemia cell and the rat mucosal mast cell.

1985 • 227 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

Chemical modification of the histidine residue in phospholipase A2 (Naja naja naja). A case of half-site reactivity.

1977 • 210 citations

Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.

1988 • 203 citations

Light activation of phospholipase A2 in rod outer segments of bovine retina and its modulation by GTP-binding proteins.

1987 • 186 citations

Regulation of phospholipid metabolism in differentiating cells from rat brain cerebral hemispheres in culture. Patterns of acetylcholine phosphocholine, and choline phosphoglycerides labeling from (methyl-14C)choline.

1976 • 164 citations

Phospholipase A2 and its zymogen from porcine pancreas. V. Interaction of phospholipase A2 and its zymogen with divalent metal ions

1974 • 159 citations

Effects of Arachidonic Acid and Its Metabolites on Antigen-Induced Histamine Release from Human Basophils in Vitro

1979 • 158 citations

Rat mast cells permeabilised with streptolysin O secrete histamine in response to Ca2+ at concentrations buffered in the micromolar range

1987 • 126 citations

Approximate dimensions of membrane lesions produced by streptolysin S and streptolysin O

1983 • 105 citations

IgE-mediated histamine release in rat basophilic leukemia cells: Receptor activation, phospholipid methylation, Ca2+ flux, and release of arachidonic acid

1981 • 103 citations

Possible Role of Arachidonic Acid and Its Metabolites in Mediator Release from Rat Mast Cells

1979 • 96 citations

Evidence for sequential signals in the induction of the arachidonic acid cascade in macrophages.

1986 • 80 citations

The kinetics of phosphoinositide hydrolysis in rat basophilic leukemia (RBL-2H3) cells varies with the type of IgE receptor cross-linking agent used.

1987 • 79 citations

G-proteins, the inositol lipid signalling pathway, and secretion

1988 • 75 citations

Phospholipase activation in the IgE-mediated and Ca2+ ionophore A23187-induced release of histamine from rat basophilic leukemia cells

1981 • 72 citations

Noncytotoxic IgE-Mediated Release of Histamine and Serotonin from Murine Mastocytoma Cells

1977 • 64 citations

Cholera toxin increases the rate of antigen-stimulated calcium influx in rat basophilic leukemia cells.

1988 • 60 citations

Phospholipase A2 stimulation during cell secretion in rat basophilic leukemia cells.

1986 • 54 citations

IgE receptor-activated calcium permeability pathway in rat basophilic leukemia cells: measurement of the unidirectional influx of calcium using quin2-buffered cells

1987 • 46 citations

Receptor-mediated release of inositol 1,4,5-trisphosphate and inositol 1,4-bisphosphate in rat basophilic leukemia RBL-2H3 cells permeabilized with streptolysin O

1989 • 42 citations

Localization of phospholipase A2 in normal and ras-transformed cells.

1988 • 41 citations

Arachidonic acid‐induced release of calcium in permeabilized human neutrophils

1987 • 34 citations

Guanosine 5′-(γ-thio)triphosphate stimulates arachidonic acid liberation in permeabilized rat peritoneal mast cells

1987 • 28 citations

Source of the arachidonic acid released on stimulation of rat basophilic leukemia cells.

1986 • 27 citations

Calcium-dependent binding of calmodulin to phospholipase A2 subunits induces enzymatic activation

1985 • 17 citations