Advances in Pancreatic Cancer Detection

Pancreatic Cancer

2000 • 7,332 citations

Cancer Statistics, 2006

2006 • 5,351 citations

p21 is a universal inhibitor of cyclin kinases

1993 • 3,408 citations

TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders

2000 • 2,354 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer

2003 • 1,572 citations

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

2003 • 1,465 citations

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

2008 • 1,243 citations

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

2003 • 1,243 citations

Expression profiling identifies microRNA signature in pancreatic cancer

2006 • 900 citations

Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer

2006 • 801 citations

MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

2006 • 769 citations

Strategies for discovering novel cancer biomarkers through utilization of emerging technologies

2008 • 732 citations

MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma

2007 • 661 citations

The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells.

1999 • 640 citations

Curcumin Potentiates Antitumor Activity of Gemcitabine in an Orthotopic Model of Pancreatic Cancer through Suppression of Proliferation, Angiogenesis, and Inhibition of Nuclear Factor-κB–Regulated Gene Products

2007 • 570 citations

Enhanced expression of transforming growth factor β isoforms in pancreatic cancer correlates with decreased survival

1993 • 518 citations

Screening for Early Pancreatic Neoplasia in High-Risk Individuals: A Prospective Controlled Study

2006 • 508 citations

Perioperative CA19-9 Levels Can Predict Stage and Survival in Patients With Resectable Pancreatic Adenocarcinoma

2006 • 507 citations

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

2004 • 504 citations

Transforming growth factor-β in cancer and metastasis

2006 • 500 citations

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

2003 • 485 citations

Biomarker Discovery from Pancreatic Cancer Secretome Using a Differential Proteomic Approach

2005 • 479 citations

High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma

2000 • 398 citations

MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology

2008 • 318 citations

Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins

2007 • 317 citations

Bortezomib Sensitizes Pancreatic Cancer Cells to Endoplasmic Reticulum Stress-Mediated Apoptosis

2005 • 301 citations

Identification of hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein I as a biomarker for pancreatic ductal adenocarcinoma by protein biochip technology.

2002 • 294 citations

Serum Diagnosis of Pancreatic Adenocarcinoma Using Surface-Enhanced Laser Desorption and Ionization Mass Spectrometry

2004 • 288 citations

Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers

2004 • 269 citations

A Mouse to Human Search for Plasma Proteome Changes Associated with Pancreatic Tumor Development

2008 • 262 citations

Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer

2009 • 261 citations

Retracted: Notch‐1 down‐regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells

2006 • 259 citations

Molecular prognostic markers in pancreatic cancer: A systematic review

2005 • 256 citations

MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.

2003 • 255 citations

Role of Macrophage Inhibitory Cytokine-1 in Tumorigenesis and Diagnosis of Cancer

2006 • 245 citations

Divergent Roles for RalA and RalB in Malignant Growth of Human Pancreatic Carcinoma Cells

2006 • 244 citations

Common Activation of Canonical Wnt Signaling in Pancreatic Adenocarcinoma

2007 • 233 citations

Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer

2000 • 232 citations

Inhibition of MUC4 Expression Suppresses Pancreatic Tumor Cell Growth and Metastasis

2004 • 231 citations

Fibroblast Activation Protein and Its Relationship to Clinical Outcome in Pancreatic Adenocarcinoma

2008 • 219 citations

K-Ras Promotes Growth Transformation and Invasion of Immortalized Human Pancreatic Cells by Raf and Phosphatidylinositol 3-Kinase Signaling

2007 • 217 citations

Serum Markers in Patients with Resectable Pancreatic Adenocarcinoma: Macrophage Inhibitory Cytokine 1 versus CA19-9

2006 • 215 citations

Focus on pancreas cancer

2002 • 215 citations

DNA Methylation Alterations in the Pancreatic Juice of Patients with Suspected Pancreatic Disease

2006 • 215 citations

Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients

2008 • 210 citations

A prospective study of K-ras mutations in the plasma of pancreatic cancer patients.

1998 • 207 citations

Evaluation of Osteopontin as Biomarker for Pancreatic Adenocarcinoma

2004 • 193 citations

Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer.

2002 • 189 citations

Prognostic Significance of Tissue Transglutaminase in Drug Resistant and Metastatic Breast Cancer

2004 • 184 citations

Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma

2002 • 178 citations

Proteomic Analysis of Chronic Pancreatitis and Pancreatic Adenocarcinoma

2005 • 175 citations

Plasma Protein Profiling for Diagnosis of Pancreatic Cancer Reveals the Presence of Host Response Proteins

2005 • 169 citations

Mucin expression profile in pancreatic cancer and the precursor lesions

2007 • 165 citations

DPC4/Smad4 Expression and Outcome in Pancreatic Ductal Adenocarcinoma

2002 • 159 citations

Detection of K-ras gene mutations in plasma DNA of patients with pancreatic adenocarcinoma: correlation with clinicopathological features.

1998 • 159 citations

Prognostic Impact of Perioperative Serum CA 19-9 Levels in Patients with Resectable Pancreatic Cancer

2010 • 156 citations

Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation.

2003 • 155 citations

CEACAM1, a Novel Serum Biomarker for Pancreatic Cancer

2007 • 155 citations

Sp1, a New Biomarker That Identifies a Subset of Aggressive Pancreatic Ductal Adenocarcinoma

2008 • 150 citations

Proteomic Profiling of Pancreatic Cancer for Biomarker Discovery

2005 • 149 citations

Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma

2002 • 148 citations

K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16INK4A, p21WAF-1, cyclin D1, erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma

2000 • 147 citations

Characterization of Proteins in Human Pancreatic Cancer Serum Using Differential Gel Electrophoresis and Tandem Mass Spectrometry

2005 • 146 citations

Identification of Potential Markers for the Detection of Pancreatic Cancer Through Comparative Serum Protein Expression Profiling

2007 • 146 citations

Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy

2007 • 145 citations

New Markers of Pancreatic Cancer Identified Through Differential Gene Expression Analyses: Claudin 18 and Annexin A8

2008 • 142 citations

Smad4-mediated TGF-β signaling in tumorigenesis

2010 • 140 citations

High Expression of HIF1a Is a Predictor of Clinical Outcome in Patients with Pancreatic Ductal Adenocarcinomas and Correlated to PDGFA, VEGF, and bFGF

2008 • 139 citations

Increased angiogenin expression in pancreatic cancer is related to cancer aggressiveness.

1996 • 136 citations

bax, but notbcl-2, influences the prognosis of human pancreatic cancer

1998 • 130 citations

Differential diagnosis of pancreatic cancer and focal pancreatitis by using EUS-guided FNA

2005 • 129 citations

Retracted: Inhibition of nuclear factor κb activity by genistein is mediated via Notch‐1 signaling pathway in pancreatic cancer cells

2005 • 123 citations

Pancreatic cancer: Pathogenesis, prevention and treatment

2006 • 123 citations

Secreted and cell surface genes expressed in benign and malignant colorectal tumors.

2001 • 122 citations

Molecular Analysis to Detect Pancreatic Ductal Adenocarcinoma in High-Risk Groups

2005 • 120 citations

Heparanase expression is a prognostic indicator for postoperative survival in pancreatic adenocarcinoma

2002 • 115 citations

Inhibition of STAT3Tyr705 Phosphorylation by Smad4 Suppresses Transforming Growth Factor β–Mediated Invasion and Metastasis in Pancreatic Cancer Cells

2008 • 114 citations

Pancreatic Cancer Serum Detection Using a Lectin/Glyco-Antibody Array Method

2008 • 113 citations

Measurement of Serum Levels of Macrophage Inhibitory Cytokine 1 Combined with Prostate-Specific Antigen Improves Prostate Cancer Diagnosis

2006 • 112 citations

Expression of MAP4K4 Is Associated with Worse Prognosis in Patients with Stage II Pancreatic Ductal Adenocarcinoma

2008 • 110 citations

Expressions of Angiogenic Factors in Pancreatic Ductal Carcinoma: A Correlative Study with Clinicopathologic Parameters and Patient Survival

2003 • 107 citations

Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma

2008 • 102 citations

Prediction of Muscle-invasive Bladder Cancer Using Urinary Proteomics

2009 • 102 citations

Recent Advances on the Molecular Mechanisms Involved in Pancreatic Cancer Progression and Therapies

2005 • 100 citations

Survivin expression is a prognostic marker in pancreatic cancer patients

2004 • 99 citations

Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer

2007 • 98 citations

Identifying Molecular Markers for the Early Detection of Pancreatic Neoplasia

2007 • 97 citations

Multiplexed Proximity Ligation Assays to Profile Putative Plasma Biomarkers Relevant to Pancreatic and Ovarian Cancer

2008 • 96 citations

Adenovirus-mediated transfer of p53 and p16INK4a results in pancreatic cancer regression in vitro and in vivo

2001 • 95 citations

Protein Profiling of Microdissected Pancreas Carcinoma and Identification of HSP27 as a Potential Serum Marker

2007 • 95 citations

S100P Is an Early Developmental Marker of Pancreatic Carcinogenesis

2006 • 95 citations

Molecular biomarkers: their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer

2006 • 93 citations

Serum vascular endothelial growth factor levels in pancreatic cancer patients correlate with advanced and metastatic disease and poor prognosis

2003 • 93 citations

Tissue Transglutaminase Regulates Focal Adhesion Kinase/AKT Activation by Modulating PTEN Expression in Pancreatic Cancer Cells

2008 • 92 citations

Hedgehog signaling in pancreas development and disease

2006 • 91 citations

MicroRNA in pancreatic cancer: Pathological, diagnostic and therapeutic implications

2009 • 88 citations

Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer

2001 • 86 citations

Increased PDX-1 expression is associated with outcome in patients with pancreatic cancer

2003 • 86 citations

Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19‐9 levels in pancreatic cancer

2008 • 85 citations

VEGF-RII Influences the Prognosis of Pancreatic Cancer

2002 • 84 citations

Pancreatic Tumor Cells with Mutant K-ras Suppress ERK Activity by MEK-Dependent Induction of MAP Kinase Phosphatase-2

2001 • 83 citations

Prognostic significance of maspin in pancreatic ductal adenocarcinoma: tissue microarray analysis of 223 surgically resected cases

2007 • 80 citations

Differential roles of alterations of p53, p16, and SMAD4 expression in the progression of intraductal papillary-mucinous tumors of the pancreas

2003 • 79 citations

Reduced membranous and ectopic cytoplasmic expression of ? -catenin correlate with cyclin D1 overexpression and poor prognosis in pancreatic cancer

2001 • 78 citations

Expression of SGLT1, Bcl-2 and p53 in Primary Pancreatic Cancer Related to Survival

2008 • 74 citations

A Small‐Molecule Antagonist of the Hedgehog Signaling Pathway

2007 • 73 citations

Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: Implications for tumor progression and clinical outcome

2008 • 71 citations

Small Molecules with EGFR-TK Inhibitor Activity

2005 • 69 citations

Developmental biology informs cancer

2003 • 67 citations

Preoperative serum carcinoembryonic antigen and carbohydrate antigen 19-9 levels for the evaluation of curability and resectability in patients with pancreatic adenocarcinoma

2007 • 66 citations

Bcl-2 expression in pancreas development and pancreatic cancer progression

2001 • 66 citations

Serum Vascular Endothelial Growth Factor/Soluble Vascular Endothelial Growth Factor Receptor 1 Ratio Is an Independent Prognostic Marker in Pancreatic Cancer

2008 • 65 citations

Expression of thrombospondin-1 in pancreatic carcinoma: correlation with microvessel density

2001 • 65 citations

Tumor M2-Pyruvate Kinase, a New Metabolic Marker for Pancreatic Cancer

2004 • 65 citations

Evaluation of urinary plasminogen activator, its receptor, matrix metalloproteinase-9, and von Willebrand factor in pancreatic cancer.

2003 • 64 citations

Angiogenesis and Cathepsin Expression Are Prognostic Factors in Pancreatic Adenocarcinoma after Curative Resection

2000 • 64 citations

Value of preoperative serum CA 19-9 levels in predicting resectability for pancreatic cancer.

2006 • 64 citations

Analysis of Ki-67 antigen expression, DNA proliferative fraction, and survival in resected cancer of the pancreas

2003 • 63 citations

Current Status of Tumor M2 Pyruvate Kinase (Tumor M2-PK) as a Biomarker of Gastrointestinal Malignancy

2007 • 63 citations

Erlotinib/gemcitabine for first-line treatment of locally advanced or metastatic adenocarcinoma of the pancreas.

2007 • 61 citations

Immunohistochemical analysis of p53 and MIB-1 in tissue specimens obtained from endoscopic ultrasonography-guided fine needle aspiration biopsy for the diagnosis of solid pancreatic masses.

2005 • 61 citations

Human Heparanase-1 Gene Expression in Pancreatic Adenocarcinoma,

2002 • 61 citations

Dysregulation of ?-Catenin Expression Correlates With Tumor Differentiation in Pancreatic Duct Adenocarcinoma

2003 • 61 citations

Detailed Tissue Expression of bcl-2, bax, bak and bcl-x in the Normal Human Pancreas and in Chronic Pancreatitis, Ampullary and Pancreatic Ductal Adenocarcinomas

2001 • 61 citations

Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas

2003 • 60 citations

Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis

2008 • 60 citations

Surrogate biomarkers in evaluating response to anti-angiogenic agents: focus on sunitinib

2007 • 60 citations

Predictors of cancer in patients with suspected pancreatic malignancy without a tissue diagnosis

2006 • 59 citations

Thrombospondin-1 expression as a prognostic predictor of pancreatic ductal carcinoma

2002 • 58 citations

Expression of thrombospondin-1 in human pancreatic adenocarcinomas: Role in matrix metalloproteinase-9 production

2001 • 58 citations

Transforming Growth Factor α Expression Drives Constitutive Epidermal Growth Factor Receptor Pathway Activation and Sensitivity to Gefitinib (Iressa) in Human Pancreatic Cancer Cell Lines

2006 • 56 citations

bcl-2 and p53 expression in resectable pancreatic adenocarcinomas: association with clinical outcome.

1996 • 56 citations

Progress on molecular markers of pancreatic cancer

2007 • 56 citations

Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer

2008 • 56 citations

Early Detection and Biomarkers in Pancreatic Cancer

2007 • 55 citations

Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis

2009 • 55 citations

PDX-1 Acts as a Potential Molecular Target for Treatment of Human Pancreatic Cancer

2008 • 55 citations

Single-Nucleotide Polymorphisms of DNA Damage Response Genes Are Associated with Overall Survival in Patients with Pancreatic Cancer

2008 • 54 citations

Polymorphisms of p16, p27, p73, and MDM2 Modulate Response and Survival of Pancreatic Cancer Patients Treated with Preoperative Chemoradiation

2008 • 51 citations

Combined detection of serum tumor markers for differential diagnosis of solid lesions located at the pancreatic head.

2007 • 51 citations

The Role of Death Receptor Ligands in Shaping Tumor Microenvironment

2006 • 51 citations

Sonic hedgehog is an early developmental marker of intraductal papillary mucinous neoplasms: clinical implications of mRNA levels in pancreatic juice

2006 • 51 citations

Improved Diagnosis of Pancreatic Adenocarcinoma Using Haptoglobin and Serum Amyloid A in a Panel Screen

2008 • 50 citations

Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma

2009 • 49 citations

The Expression Pattern of PDX-1, SHH, Patched and Gli-1 Is Associated with Pathological and Clinical Features in Human Pancreatic Cancer

2008 • 49 citations

Dual targeting of Raf and VEGF receptor 2 reduces growth and metastasis of pancreatic cancer through direct effects on tumor cells, endothelial cells, and pericytes

2008 • 48 citations

Expression of K homology domain Containing protein Overexpressed in cancer in pancreatic FNA for diagnosing adenocarcinoma of pancreas

2007 • 48 citations

Epidermal Growth Factor Receptor–Related Protein Inhibits Cell Growth and Invasion in Pancreatic Cancer

2006 • 48 citations

Preoperative evaluation of pancreatic adenocarcinoma

2008 • 46 citations

Comparative proteomic analysis for the detection of biomarkers in pancreatic ductal adenocarcinomas

2007 • 45 citations

CA 19-9 as a Predictor for Response and Survival in Advanced Pancreatic Cancer Patients Treated With Chemoradiotherapy

2008 • 45 citations

Potent Inhibitors of the Hedgehog Signaling Pathway

2008 • 44 citations

Tissue MicroArray Analyses of Pancreatic Duodenal Homeobox‐1 in Human Cancers

2005 • 44 citations

Expression of Smad2 and Smad4 in cervical cancer: absent nuclear Smad4 expression correlates with poor survival

2008 • 43 citations

Proteomic Classification of Pancreatic Adenocarcinoma Tissue Using Protein Chip Technology

2006 • 43 citations

Apoptotic index or a combination of Bax/Bcl-2 expression correlate with survival after resection of pancreatic adenocarcinoma

2005 • 43 citations

Epidermal growth factor receptor inhibition strategies in pancreatic cancer: past, present and the future.

2007 • 42 citations

β-Catenin is a promising key factor in the SDF-1/CXCR4 axis on metastasis of pancreatic cancer

2007 • 41 citations

Transforming growth factor beta I expression in benign and malignant prostatic tumors

1994 • 40 citations

Comparison of circulating MMP-9, TIMP-1 and CA19-9 in the detection of pancreatic cancer.

2010 • 39 citations

Pancreas duodenal homeobox-1 expression and significance in pancreatic cancer

2007 • 37 citations

Clinical utility of quantitative RT‐PCR targeted to α1,4‐N‐acetylglucosaminyltransferase mRNA for detection of pancreatic cancer

2006 • 36 citations

Tumor M2-Pyruvate Kinase as Tumor Marker in Exocrine Pancreatic Cancer A Meta-Analysis

2007 • 36 citations

Loss of p27 Expression Is Associated with Poor Prognosis in Stage I–II Pancreatic Cancer

2003 • 36 citations

TPS, CA 19-9, VEGF-A, and CEA as Diagnostic and Prognostic Factors in Patients with Mass Lesions in the Pancreatic Head

2008 • 35 citations

A Review of Kinases Implicated in Pancreatic Cancer

2009 • 35 citations

Clinical contribution of bcl-2, p53 and Ki-67 proteins in pancreatic ductal adenocarcinoma.

1998 • 34 citations

Diagnostic and prognostic biomarkers in pancreatic carcinoma.

2009 • 33 citations

Assessment of soluble angiogenic markers in pancreatic cancer

2008 • 33 citations

Caveolin-1: a marker for pancreatic cancer diagnosis

2008 • 33 citations

Antiangiogenic Treatment with Three Thrombospondin-1 Type 1 Repeats versus Gemcitabine in an Orthotopic Human Pancreatic Cancer Model

2005 • 32 citations

Pancreatic cancer biomarkers discovery by surface-enhanced laser desorption and ionization time-of-flight mass spectrometry

2009 • 32 citations

Methods and rationale for the early detection of pancreatic cancer. Highlights from the "2010 ASCO Gastrointestinal Cancers Symposium". Orlando, FL, USA. January 22-24, 2010.

2010 • 31 citations

Apoptosis and Expression of Bcl-2 and Bax Proteins in Invasive Ductal Carcinoma of the Pancreas

2001 • 31 citations

Tumor-associated CD75s- and iso-CD75s-gangliosides are potential targets for adjuvant therapy in pancreatic cancer

2008 • 30 citations

Expression of Ki-67, p53, and K-ras in chronic pancreatitis and pancreatic ductal adenocarcinoma

2005 • 29 citations

New Aspects of Regulatory Signaling Pathways and Novel Therapies in Pancreatic Cancer

2008 • 28 citations

Bortezomib is ineffective in an orthotopic mouse model of pancreatic adenocarcinoma

2008 • 28 citations

Molecular prognostic factors in patients with pancreatic cancer

2007 • 27 citations

Tumor M2 pyruvate kinase: a tumor marker and its clinical application in gastrointestinal malignancy

2008 • 27 citations

MUC1 Is a Useful Molecular Marker for Malignant Intraductal Papillary Mucinous Neoplasms in Pancreatic Juice Obtained From Endoscopic Retrograde Pancreatography

2010 • 25 citations

Correlation Between TGF-β1 and p21 (WAF1/CIP1) Expression and Prognosis in Resectable Invasive Ductal Carcinoma of the Pancreas

2001 • 25 citations

Expression of Survivin in pancreatic cancer and its correlation to expression of Bcl-2

2004 • 24 citations

p27Kip1 expression is reduced in pancreatic carcinoma but has limited prognostic value

2003 • 24 citations

CXCR2 and RET Single Nucleotide Polymorphisms in Pancreatic Cancer

2008 • 24 citations

Expression of the bcl-2 gene and its significance in human pancreatic carcinoma.

2002 • 23 citations

MALDI/SELDI Protein Profiling of Serum for the Identification of Cancer Biomarkers

2008 • 23 citations

Bcl-XL Protein Levels Determine Apoptotic Index in Pancreatic Carcinoma

2005 • 22 citations

Ras‐Driven Transformation of Human Nestin‐Positive Pancreatic Epithelial Cells

2008 • 20 citations

The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity

2004 • 20 citations

Expression of the tumor suppressor gene maspin and its significance in intraductal papillary mucinous neoplasms of the pancreas.

2008 • 19 citations

Tumor marker M2-pyruvate-kinase in differential diagnosis of chronic pancreatitis and pancreatic cancer.

2008 • 17 citations

Usefulness of Plasma Vascular Endothelial Growth Factor in the Diagnosis of Pancreatic Carcinoma

2005 • 16 citations

Expression of K Homology Domain Containing Protein (KOC) in Pancreatic Cytology with Corresponding Histology

2009 • 15 citations

Maspin is Useful in the Distinction of Pancreatic Adenocarcinoma From Chronic Pancreatitis

2007 • 15 citations

alpha-, beta- and chi-catenin expression in human pancreatic cancer.

2004 • 13 citations

Biomarkers in the diagnosis and early detection of pancreatic cancer

2009 • 13 citations

Circulating vascular endothelial growth factor and interferon-gamma-inducible protein-10 levels in pancreatic cancer during chemotherapy.

2005 • 12 citations

Antiangiogenic therapy in human gastrointestinal malignancies

2006 • 11 citations

Pancreatic cancer: a plea for good and comprehensive morphological studies

2008 • 9 citations

[Relationship between the expression of beta-cat, cyclin D1 and c-myc and the occurance and biological behavior of pancreatic cancer].

2003 • 9 citations

Differential Diagnosis of Pancreatic Tumors by Molecular Analysis of Clinical Specimens

2008 • 8 citations

Translational research in pancreatic cancer. Highlights from the "44th ASCO Annual Meeting". Chicago, IL, USA. May 30 - June 3, 2008.

2008 • 7 citations

Diagnostic performance of MUC1 for pancreatic ductal adenocarcinoma: A meta-analysis

2008 • 4 citations

CD44 isoforms expression in intraductal and invasive pancreatic cancer and its correlation to p53 gene mutations.

1999 • 3 citations

CAV1 (caveolin 1, caveolae protein, 22kDa)

2011 • 2 citations