The Inositol Phosphate/Diacylglycerol Pathway in MA-10 Leydig Tumor Cells

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

The Metabolism of Phosphoinositide-Derived Messenger Molecules

1986 • 717 citations

Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*

1981 • 596 citations

Techniques of Lipidology: isolation, analysis and identification of lipids

1974 • 540 citations

Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.

1986 • 415 citations

Insulin-Stimulated Hydrolysis of a Novel Glycolipid Generates Modulators of cAMP Phosphodiesterase

1986 • 383 citations

Inositol phosphates: synthesis and degradation.

1988 • 359 citations

The temporal integration of the aldosterone secretory response to angiotensin occurs via two intracellular pathways.

1984 • 332 citations

Antiphosphotyrosine Recovery of Phospholipase C Activity After EGF Treatment of A-431 Cells

1988 • 324 citations

Thyrotropin-releasing hormone rapidly activates the phosphodiester hydrolysis of polyphosphoinositides in GH3 pituitary cells. Evidence for the role of a polyphosphoinositide-specific phospholipase C in hormone action.

1983 • 292 citations

Epidermal growth factor stimulates the production of phosphatidylinositol monophosphate and the breakdown of polyphosphoinositides in A431 cells.

1987 • 230 citations

Rapid accumulation of inositol phosphates in isolated rat superior cervical sympathetic ganglia exposed to V1-vasopressin and muscarinic cholinergic stimuli

1984 • 224 citations

Epidermal growth factor stimulates the rapid accumulation of inositol (1,4,5)-trisphosphate and a rise in cytosolic calcium mobilized from intracellular stores in A431 cells.

1987 • 202 citations

Luteinizing hormone increases inositol trisphosphate and cytosolic free Ca2+ in isolated bovine luteal cells.

1987 • 194 citations

Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5- and inositol 1,3,4-trisphosphate in hepatocytes. Differential inhibition by pertussis toxin and phorbol 12-myristate 13-acetate.

1987 • 168 citations

Lack of association of epidermal growth factor-, insulin-, and serum-induced mitogenesis with stimulation of phosphoinositide degradation in BALB/c 3T3 fibroblasts.

1986 • 156 citations

Role of calcium fluxes in the sustained phase of angiotensin II-mediated aldosterone secretion from adrenal glomerulosa cells.

1985 • 141 citations

Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells

1978 • 141 citations

Luteinizing hormone stimulates the formation of inositol trisphosphate and cyclic AMP in rat granulosa cells. Evidence for phospholipase C generated second messengers in the action of luteinizing hormone

1986 • 139 citations

Regulation of gonadotropin receptors and gonadotropin responses in a clonal strain of Leydig tumor cells by epidermal growth factor.

1981 • 137 citations

Regulation of epidermal growth factor-stimulated formation of inositol phosphates in A-431 cells by calcium and protein kinase C.

1988 • 131 citations

Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line.

1985 • 125 citations

The role of Ca2+ in steroidogenesis in Leydig cells. Stimulation of intracellular free Ca2+ by lutropin (LH), luliberin (LHRH) agonist and cyclic AMP

1986 • 106 citations

Neurohypophysial peptides design of tissue-specific agonists and antagonists

1981 • 99 citations

Mechanism of the Inhibitory Action of Epidermal Growth Factor on Testicular Androgen Biosynthesis in Vitro*

1982 • 93 citations

Inhibition of choriogonadotropin-activated steroidogenesis in cultured Leydig tumor cells by the Rp diastereoisomer of adenosine 3′,5′-cyclic phosphorothioate.

1987 • 86 citations

Identification and Characterization of Arginine Vasopressin Receptors in the Rat Testis*

1985 • 82 citations

Removal of the surface-bound human choriogonadotropin results in the cessation of hormonal responses in cultured Leydig tumor cells.

1981 • 80 citations

Stimulatory effects of epidermal growth factor on steroidogenesis in Leydig cells

1986 • 78 citations

Identification and characterization of arginine vasopressin-like substances in the rat testis.

1985 • 64 citations

Vasopressin Induces Breakdown of Membrane Phosphoinositides in Adrenal Glomerulosa and Fasciculata Cells*

1986 • 59 citations

Inositol Phosphates Accumulation in Ovarian Granulosa After Stimulation by Luteinizing Hormone1

1987 • 59 citations

Arginine Vasopressin in the Testis: An Intragonadal Peptide Control System*

1986 • 58 citations

Epidermal growth factor activates steroid biosynthesis in cultured Leydig tumor cells without affecting the levels of cAMP and potentiates the activation of steroid biosynthesis by choriogonadotropin and cAMP.

1987 • 52 citations

Vasopressin Stimulates Phosphatidylinositol Turnover and Aldosterone Synthesis in Rat Adrenal Glomerulosa Cells: Comparison with Angiotensin II*

1986 • 49 citations

Direct inhibition of rat testicular androgen biosynthesis by arginine vasotocin. Studies on mechanisms of action.

1982 • 48 citations

Epidermal growth factor stimulates formation of inositol phosphates in BALB/c/3T3 cells pretreated with cholera toxin and isobutylmethylxanthine.

1988 • 43 citations

Arginine Vasopressin as an Intragonadal Hormone in Brattleboro Rats: Presence of a Testicular Vasopressin-Like Peptide and Functional Vasopressin Receptors*

1986 • 42 citations

Na+ modulates the affinity of the lutropin/choriogonadotropin receptor.

1984 • 40 citations

The mechanisms of LHRH agonist action in gonadal tissues

1985 • 38 citations

Effects of Prostaglandin F_2αand a Gonadotropin-Releasing Hormone Agonist on Inositol Phospholipid Metabolism in Isolated Rat Corpora Lutea of Various Ages*

1988 • 32 citations

Ca+2 Is an Inhibitor of Adenylate Cyclase in MA-10 Leydig Tumor Cells*

1988 • 27 citations

Inhibition of gonadotropin-responsive adenylate cyclase in MA-10 Leydig tumor cells by epidermal growth factor.

1988 • 26 citations

12‐O‐Tetradecanoyl phorbol 13‐acetate stimulates the myristylation of an ∼ 82 kDa protein in HL‐60 cells

1987 • 13 citations

Vasopressin induces breakdown of phosphoinositides in adrenal tumor Y-1 cells without a steroidogenic effect

1988 • 9 citations

Measurement of phosphoinositide pools in WRK-1 cells

1987 • 5 citations