Catalytic Aspects of Enzymatic Racemization

Catalysis in chemistry and enzymology

1969 • 3,236 citations

A General Mechanism for Vitamin B₆-catalyzed Reactions¹

1954 • 627 citations

The Enzymatic Oxidation of Pyridoxine and Pyridoxamine Phosphates

1961 • 547 citations

Alkylation and Identification of the Histidine Residues at the Active Site of Ribonuclease

1963 • 423 citations

Carbohydrate Metabolism and Its Disorders.

1969 • 415 citations

Conformation and reaction specificity in pyridoxal phosphate enzymes.

1966 • 353 citations

D-Amino Acids in Animals

1969 • 324 citations

THE FEEDBACK CONTROL OF SUGAR NUCLEOTIDE BIOSYNTHESIS IN LIVER

1964 • 310 citations

The β-Ketoadipate Pathway

1973 • 272 citations

THE ENZYMIC INTERCONVERSION OF URIDINE DIPHOSPHOGALACTOSE AND URIDINE DIPHOSPHOGLUCOSE

1957 • 228 citations

Mechanism of <scp>d</scp> -Cycloserine Action: Alanine Racemase from Escherichia coli W

1972 • 218 citations

The Enzymes of the Galactose Operon in Escherichia coli

1964 • 211 citations

Properties and Conformation of the Histidine Residues at the Active Site of Ribonuclease

1963 • 201 citations

Amino acid racemization reactions and their geochemical implications

1975 • 185 citations

The Relation of Spectral Changes and Tritium Exchange Reactions to the Mechanism of Tryptophanase-catalyzed Reactions

1967 • 178 citations

d-ALANINE FORMATION: A RACEMASE IN STREPTOCOCCUS FAECALIS

1951 • 176 citations

COMPETITIVE INHIBITION OF ENZYMATIC REACTIONS BY OXAMYCIN

1960 • 174 citations

Purification and mechanism of action of proline racemase

1968 • 173 citations

Biosynthesis of alginate

1971 • 171 citations

Formation of Guanosine Diphosphate l-Fucose from Guanosine Diphosphate d-Mannose

1960 • 169 citations

Biosynthesis of alginate

1971 • 158 citations

Studies on the Biosynthesis of Guanosine Diphosphate l-Fucose

1961 • 154 citations

Regulation of catabolic pathways in Pseudomonas

1971 • 149 citations

Nonribosomal polypeptide synthesis on polyenzyme templates

1973 • 145 citations

Chemistry and Biosynthesis of the Poly(γ-d-glutamyl) Capsule in Bacillus licheniformis

1973 • 143 citations

PEPTIDYL TRANSFERS IN GRAMICIDIN S BIOSYNTHESIS FROM ENZYME-BOUND THIOESTER INTERMEDIATES

1969 • 136 citations

The mechanism of the action of notatin

1949 • 118 citations

Mechanisms of Enzyme Action

1966 • 117 citations

Reaction mechanism and structure of the active site of proline racemase

1975 • 117 citations

THE RÔLE OF XYLULOSE 5-PHOSPHATE IN XYLOSE METABOLISM OF LACTOBACILLUS PENTOSUS

1956 • 115 citations

The enzymic conversion of glucosamine to galactosamine

1959 • 115 citations

Catalytic Racemization of Amino Acids by Pyridoxal and Metal Salts

1952 • 107 citations

Theory of the process of amino-acid metabolism, catalysed by pyridoxal enzymes.

1953 • 107 citations

Mutarotation of Sugars in Solution: Part I

1968 • 101 citations

Stereochemical Aspects of Pyridoxal Phosphate Catalysis

1971 • 101 citations

Metabolism of Proline and of Hydroxyproline

1970 • 100 citations

Biosynthesis of alginate

1971 • 100 citations

Enzymic synthesis of N-acetyl-D-mannosamine

1958 • 100 citations

OXAMYCIN, A COMPETITIVE ANTAGONIST OF THE INCORPORATION OF D-ALANINE INTO A URIDINE NUCLEOTIDE IN STAPHYLOCOCCUS AUREUS

1959 • 99 citations

Control of Aspartate β-Decarboxylase Activity by Transamination

1964 • 96 citations

Origin of the Word Climate

1954 • 94 citations

STUDIES ON THE ENZYMIC REDUCTION OF AMINO ACIDS

1957 • 93 citations

Purification and properties of uridine diphosphate galactose-4-epimerase from yeast

1968 • 93 citations

The stereoisomers of α∈-diaminopimelic acid. 3. Properties and distribution of diaminopimelic acid racemase, an enzyme causing interconversion of the <scp>ll</scp> and meso isomers

1957 • 90 citations

Mutarotation of Sugars in Solution: PART II

1969 • 87 citations

Xylulose-5-phosphate, a new intermediate in the pentose phosphate cycle

1955 • 87 citations

Stereochemical Evidence for the Evolution of Pyridoxal-phosphate Enzymes of Various Function from a Common Ancestor

1974 • 86 citations

Biological catalysis of mutarotation of glucose

1952 • 83 citations

The Mechanism of Action of the Enzyme Uridine Diphosphoglucose 4-Epimerase

1971 • 82 citations

The Sialic Acids

1965 • 82 citations

Pentose phosphate isomerase and epimerase from animal tissues

1956 • 81 citations

The Enzymes of the Galactose Operon in Escherichia coli

1969 • 79 citations

Purification of Uridine Diphosphate Galactose-4-epimerase from Yeast, and the Identification of Protein-bound Diphosphopyridine Nucleotide

1960 • 78 citations

Biosynthesis of Uridine Diphosphate D-Xylose. I. Uridine Diphosphate Glucuronate Carboxy-lyase of Wheat Germ^*

1965 • 74 citations

The Biosynthesis of N-Acetylgalactosamine

1959 • 74 citations

A basis for utlization of unnatural pentoses and pentitols by Aerobacter aerogenes.

1965 • 74 citations

THE PURIFICATION OF PHOSPHOKETOPENTOEPIMERASE FROM LACTOBACILLUS PENTOSUS AND THE PREPARATION OF XYLULOSE 5-PHOSPHATE

1956 • 74 citations

Metabolism of Propionic Acid in Animal Tissues

1962 • 71 citations

Biosynthesis of Uronic Acids by Skin Enzymes

1962 • 69 citations

Arginine Racemase of Pseudomonas graveolens

1971 • 68 citations

Mandelic acid racemase from Pseudomonas putida. Purification and properties of the enzyme

1970 • 66 citations

INTERRELATION BETWEEN ACTIVATION AND POLYMERIZATION IN GRAMICIDIN S BIOSYNTHESIS

1969 • 63 citations

Hydroxyproline Metabolism

1959 • 63 citations

Methylmalonyl Coenzyme A Racemase Defect: Another Cause of Methylmalonic Aciduria

1972 • 63 citations

The Mechanism of 6-Deoxyhexose Synthesis

1968 • 61 citations

Uridine Diphosphate-4-Keto-Glucose, an Intermediate in the Uridine Diphosphate-Galactose-4-Epimerase Reaction

1971 • 59 citations

Epimerization of disaccharides by enzyme preparations from Ruminococcus albus

1967 • 59 citations

THE ENZYMATIC CONVERSION OF MANDELIC ACID TO BENZOIC ACID I

1953 • 58 citations

Kinetic and Structural Studies of Hydroxyproline 2-Epimerase

1970 • 58 citations

Purification and Properties of Lactate Racemase from Lactobacillus sake

1968 • 57 citations

Coenzyme content of purified alanine racemase from Pseudomonas

1969 • 57 citations

<scp>d</scp> -Lysine Catabolic Pathway in Pseudomonas putida: Interrelations with <scp>l</scp> -Lysine Catabolism

1974 • 57 citations

Crystalline amino acid racemase with low substrate specificity

1969 • 56 citations

Some considerations concerning the nature of the enzymic galactose-glucose conversion

1956 • 54 citations

Anomalous mutarotation of glucose 6-phosphate. An example of intramolecular catalysis

1970 • 54 citations

Racemization of D- or L-alanine by crystalline tyrosine phenol-lyase from Eshherichia intermedia

1970 • 54 citations

The Sialic Acids

1965 • 53 citations

Enzymatic Racemization of β-Hydroxybutyryl-S-CoA and the Stereospecificity of Enzymes of the Fatty Acid Cycle¹

1955 • 52 citations

PENTOSE FERMENTATION BY LACTOBACILLUS PLANTARUM

1958 • 52 citations

Mutarotase from Penicillium notatum

1960 • 51 citations

The Isolation, Purification, and Properties of Methylmalonyl Racemase

1963 • 51 citations

Studies on Escherichia coli Enzymes Involved in the Synthesis of Uridine Diphosphate- N -Acetyl-Muramyl-Pentapeptide

1972 • 49 citations

On the Mechanism of Action of the Antibiotic O -Carbamyl- <scp>d</scp> -Serine in Streptococcus faecalis

1966 • 48 citations

Inducible Degradation of Hydroxyproline in Pseudomonas putida: Pathway Regulation and Hydroxyproline Uptake

1969 • 48 citations

Purification and Properties of Inducible Hydroxyproline 2-Epimerase from Pseudomonas

1964 • 47 citations

Glutamic Acid Racemase from Lactobacillus arabinosus

1960 • 47 citations

Studies on Amino Acid Racemases

1969 • 47 citations

4-Hydroxy-2-ketoglutarate Aldolase of Rat Liver

1967 • 47 citations

3 Stereospecificity of Enzymic Reactions

1970 • 47 citations

Identification and partial characterization of inositol; NAD⁺ epimerase and inosose: NAD(P)H reductase from the fat body of the American cockroach, Periplaneta americana

1973 • 46 citations

Wirkungsmechanismus der Glyoxalase I

1956 • 45 citations

D2O-Alanine exchange reactions catalyzed by Alanine Racemase and Glutamic Pyruvic Transaminase

1974 • 44 citations

Mandelate racemase from Pseudomonas putida. Subunit composition and absolute divalent metal ion requirement

1974 • 44 citations

Mandelic acid racemase from Pseudomonas putida. Evidence favoring a carbanion intermediate in the mechanism of action

1970 • 43 citations

Arginine Racemase of Pseudomonas graveolens

1971 • 43 citations

The nature of the enzyme bound intermediates in gramicidin s biosynthesis

1970 • 42 citations

d(−)β-hydroxybutyryl CoA dehydrogenase

1955 • 41 citations

The absolute configuration of methylmalonyl-CoA

1964 • 41 citations

Studies on the Mechanism of Action of Uridine Diphosphate Galactose 4-Epimerase

1973 • 41 citations

Basische Thiole als Katalysatoren der intramolekularen Cannizzaro‐Reaktion

1955 • 41 citations

Biological Mechanisms Involved in the Formation of Deoxy Sugars: Enzymatic Hydrogen Mediation

1973 • 40 citations

Alanine Racemase from Staphylococcus aureus: Conformation of Its Substrates and Its Inhibitor, D-Cycloserine

1966 • 39 citations

The Mechanism of Pentose Phosphate Isomerization and Epimerization Studied with T2O and H2O18

1961 • 39 citations

THE FORMS OF LACTIC ACID PRODUCED BY PURE AND MIXED CULTURES OF BACTERIA

1926 • 39 citations

Uridine diphosphate N-acetyl-d-glucosamine 2-epimerase from rat liver

1972 • 37 citations

The mechanism of the galactose-glucose interconversion in Lactobacillus bulgaricus

1956 • 37 citations

Active-site sulfhydryl groups of yeast alcohol dehydrogenase

1973 • 37 citations

Uridine diphosphate-N-acetylglucosamine-4-epimerase from Bacillus subtilus

1959 • 37 citations

Adenosine Triphosphate and Pyrophosphate Dependent Phenylalanine Racemase of Bacillus brevis NAGANO*

1968 • 36 citations

METABOLISM OF L-LYSINE BY BACTERIAL ENZYMES

1960 • 36 citations

FORMATION OF XYLULOSE PHOSPHATE FROM RIBOSE PHOSPHATE IN SPLEEN EXTRACTS

1954 • 36 citations

Partial Purification and Characterization of an Aspartate Racemase from Streptococcus faecalis

1972 • 35 citations

Mandelate racemase. V. Mandelate racemase from Pseudomonas putida. Magnetic resonance and kinetic studies of the mechanism of catalysis

1975 • 35 citations

Further Purification and Properties of Adenosine Triphosphate-dependent Phenylalanine Racemase of Bacillus brevis NAGANO*

1969 • 35 citations

4-Uloses as Intermediates in Enzyme-Nicotinamide Adenine Dinucleotide-mediated Oxidoreductase Mechanisms

1973 • 34 citations

The Stereochemistry of Pyridoxal Phosphate Enzymes

1973 • 34 citations

Purification and properties of -N- 2′-epimerase from rat liver

1973 • 34 citations

The absolute configuration of methylmalonyl CoA and stereochemistry of the methylmalonyl CoA mutase reaction

1964 • 33 citations

The Enzymatically Catalyzed Mutarotation. The Mechanism of Action of Mutarotase (Aldose 1-Epimerase) from Escherichia coli

1971 • 33 citations

The Reductive Inactivation of UDPgalactose-4-Epimerase from Yeast and E. coli

1970 • 32 citations

The galactose-glucose conversion in isotopic water

1956 • 32 citations

19 Fumarase and Crotonase

1971 • 32 citations

Reversible changes of ordered polypeptide structures in oxidized and reduced epimerase.

1968 • 31 citations

Molecular transitions in an induced enzyme with enhanced fluorescence

1965 • 30 citations

Assay and properties of diaminopimelate epimerase from Bacillus megaterium

1969 • 30 citations

A New Enzyme in the Conversion of Propionyl Coenzyme A to Succinyl Coenzyme A

1961 • 30 citations

Studies on amino acid racemases II. Purification and properties of the glutamate racemase from Lactobacillus fermenti

1969 • 29 citations

Ionic strength dependent dissociation and association of yeast uridine diphosphate galactose 4-epimerase subunits

1971 • 29 citations

Mechanism of action of uridine diphosphate N-acetylglucosamine 2-epimerase

1970 • 29 citations

Lactate racemase. Direct evidence for an α-carbonyl intermediate

1974 • 28 citations

Crystalline L-Ribulose 5-Phosphate 4-Epimerase from Escherichia coli

1968 • 28 citations

On the Mechanism of the Pentose Phosphate Epimerases

1972 • 28 citations

Lactic Acid Racemization in Clostridium butylicum. Evidence for a Direct Internal Hydride Shift^*

1965 • 28 citations

On the mechanism of N-acetylmannosamine formation

1960 • 28 citations

Enzymatic Synthesis of Cytidine Diphosphate 3,6-Dideoxyhexoses

1966 • 28 citations

l-Ribulose 5-Phosphate 4-Epimerase from Aerobacter aerogenes

1972 • 27 citations

The synthesis of thymidine-linked sugars III. On the mechanism of thymidine diphosphate-l-rhamnose formation

1961 • 27 citations

Interaction of Nucleotides with Liver Uridine Diphosphate-glucose-4′-epimerase

1974 • 26 citations

Alanine racemase of Pseudomonas

1974 • 25 citations

Intramolecular hydrogen transfer catalyzed by UDP-D-glucose 4′-epimerase from Escherichia coli

1970 • 25 citations

Glutamic acid racemase from Lactobacillusfermenti purification and properties

1961 • 24 citations

On the mechanism of the UDP-D-glucose-4′-epimerase evidence for a 3-keto-hexose intermediate

1971 • 24 citations

Synthesis and proof of structure of tritiated glucose and its use in the study of the mechanism of UPPGal-C-4-epimerase

1963 • 24 citations

Uridine diphosphate N-acetyl-d-glucosamine 2-epimerase from rat liver

1972 • 23 citations

Mandelate racemase from Pseudomonas putida. Affinity labeling of the enzyme by D, L-α-phenylglycidate in the presence of magnesium ion

1974 • 23 citations

l-Ribulose-5-phosphate-d-xylulose-5-phosphate stereoisomerase and its role in l-arabinose fermentation

1957 • 23 citations

Concerted reduction of yeast uridine diphosphate galactose 4-epimerase

1971 • 22 citations

Racemization of Phenylalanine by Adenosine Triphosphate-dependent Phenylalanine Racemase of Bacillus brevis Nagano*

1971 • 22 citations

l-Ribulose 5-Phosphate 4-Epimerase of Aerobacter aerogenes

1970 • 22 citations

PROPERTIES OF THE LACTIC ACID-RACEMIZING ENZYME OF CLOSTRIDIUM BUTYLICUM

1939 • 22 citations

[110] UDP-N-acetyl-d-glucosamine 2′-epimerase

1966 • 22 citations

10 Epimerases

1972 • 22 citations

Studies on the Mechanism of Action of Uridine Diphosphate-galactose-4-epimerase

1972 • 22 citations

Steroidepimerase—ein neues enzyme des oestrogenstoff-wechsels

1968 • 21 citations

Production of racemic lactic acid in Pediococcus cerevisiae cultures by two lactate dehydrogenases

1975 • 21 citations

Effect of pH on the reactivity of the active-site sulfhydryl groups in yeast alcohol dehydrogenase

1974 • 21 citations

Some properties of mandelate racemase from Pseudomonas fluorescens

1966 • 21 citations

Mutarotase. Photooxidation reactions and nature of the enzyme catalysis

1973 • 21 citations

Interaction between uridine diphosphate galactose and uridine diphosphate galactose 4-epimerase from Escherichia coli

1972 • 20 citations

Allantoin racemase: A new enzyme from Pseudomonas species

1975 • 20 citations

Specific tritium labeling of uridine diphosphogalactose 4-epimerase by D-[1-3H]galactose

1972 • 19 citations

Uridine diphosphoglucose 4-epimerase: Kinetic isotope effect

1970 • 19 citations

The Intermediate in the Uridine Diphosphate Galactose 4-Epimerase Reaction

1973 • 18 citations

The inhibition of proline racemase by a transition state analogue: Δ-1-Pyrroline-2-carboxylate

1974 • 17 citations

Inhibition of alanine racemase by aminoxyacetic acid

1967 • 17 citations

Mechanism of cellobiose epimerase

1969 • 17 citations

Uridine Diphosphate Galacturonate 4-Epimerase from the Blue-Green Alga Anabaena flos-aquae

1974 • 16 citations

Substrate stereochemical requirements in the reductive inactivation of uridine diphosphate galactose 4-epimerase by sugar and 5'-uridine monophosphate

1973 • 15 citations

Mutarotase in Higher Plants: Distribution and Properties

1966 • 15 citations

The Mechanism of Uridine Diphosphate-Sugar-4-Epimerase Reactions

1974 • 14 citations

Epimerisation of naturally occurring C-19 steroid allylic alcohols by rat liver preparations

1969 • 14 citations

Occurrence of arginine racemase in bacterial extract

1967 • 13 citations

A general NMR method for the assay of racemase activity with optically active or optically inactive substrates

1975 • 13 citations

4-Uloses as Intermediates in Enzyme-Nicotinamide Adenine Dinucleotide-mediated Oxidoreductase Mechanisms

1973 • 13 citations

Mutarotase: Still candidate for the role of membrane glucose carrier?

1970 • 13 citations

Active site comparison of mutarotase with the glucose carrier in human erythrocytes

1970 • 12 citations

The metabolism of hydroxyproline

1973 • 12 citations

Inhibition of kidney mutarotase activity by glucose, urea and guanidine hydrochloride

1963 • 10 citations

Mutarotase (aldose-1-epimerase) catalyzed anomerization of glucose-6-phosphate

1974 • 10 citations

Analysis of a crystalline mutarotase from bovine kidney cortex

1973 • 10 citations

Kinetics of mutarotation of glucose catalyzed by purified hog kidney mutarotase

1964 • 10 citations

l-Ribulose 5-Phosphate 4-Epimerase from Aerobacter aerogenes

1972 • 9 citations

Quantitative relationships between glucose reabsorption and mutarotation by dog kidney invivo

1972 • 9 citations

Electrophilic substitution at saturated carbon. XXXIV. Isoinversion as a mechanistic component in base-catalyzed hydrogen-deuterium exchange between carbon acids and medium

1967 • 8 citations

Lactic acid racemization in Cl.butylicum: 18O exchange studies

1966 • 8 citations

Hydroxyproline-2-epimerase of pseudomonas: Active-site peptides

1975 • 8 citations

A RACEMIZING ENZYME SYSTEM OF LACTOBACILLUS PLANTARUM

1965 • 7 citations

On the Metabolism of Organic Acids by Clostridium acetobutylicum

1961 • 7 citations

myo-Inosose-2 reactivation of reduced UDP-d-galactose 4-epimerase from Escherichia coli

1972 • 6 citations

Freedom of hydroxyproline-2-epimerase from pyridoxal phosphate

1963 • 6 citations

Induced Reoxidation and Reactivation of a Reduced Uridine Diphosphate Galactose-4-epimerase Complex

1974 • 4 citations

Epimerization of an intermediary metabolite of norethynodrel by a 3β-hydroxy-Δ5(10)-steroid epimerase

1971 • 4 citations

Enzymatic Racemization of Leucine and α-Aminobutyrate

1969 • 3 citations

Sugar Transport Systems and the Evolution of Mutarotases

1973 • 1 citations

On the Metabolism of Organic Acids by Clostridium acetobutylicum

1961 • 1 citations