Structure/function analysis of interleukin-2-toxin (DAB486-IL-2). Fragment B sequences required for the delivery of fragment A to the cytosol of target cells.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (24)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
DNA sequencing with chain-terminating inhibitors
1977 • 69,181 citations
Molecular Cloning. A Laboratory Manual
1983 • 27,328 citations
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors
1985 • 15,222 citations
Current protocols in molecular biology
1988 • 7,584 citations
Analysis of membrane and surface protein sequences with the hydrophobic moment plot
1984 • 2,234 citations
Using mini-prep plasmid DNA for sequencing double stranded templates with Sequenase.
1988 • 552 citations
An improved procedure for protein staining in polyacrylamide gels with a new type of Coomassie Brilliant Blue
1972 • 498 citations
The interleukin 2 receptor. Functional consequences of its bimolecular structure.
1987 • 409 citations
‘ATG vectors’ for regulated high-level expression of cloned genes in Escherichia coli
1985 • 392 citations
Diphtheria Toxin and Related Proteins
1973 • 285 citations
Diphtheria toxin receptor binding domain substitution with interleukin-2: genetic construction and properties of a diphtheria toxin-related interleukin-2 fusion protein
1987 • 236 citations
Interleukin 2 receptor-targeted cytotoxicity. Interleukin 2 receptor-mediated action of a diphtheria toxin-related interleukin 2 fusion protein.
1988 • 220 citations
An immunological study of the diphtheria toxin molecule
1972 • 182 citations
Binding of triton X-100 to diphtheria toxin, crossreacting material 45, and their fragments.
1976 • 139 citations
Secondary Structure of Diphtheria Toxin and Its Fragments Interacting with acidic Liposomes Studied by Polarized Infrared Spectroscopy
1989 • 134 citations
Primary structure of diphtheria toxin fragment B: structural similarities with lipid-binding domains.
1980 • 77 citations
Cloned fragment of diphtheria toxin linked to T cell-specific antibody identifies regions of B chain active in cell entry.
1986 • 76 citations
Thyrotropin-releasing hormone-diphtheria toxin-related polypeptide conjugates. Potential role of the hydrophobic domain in toxin entry.
1983 • 70 citations
High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coli
1987 • 55 citations
Integration of corynebacteriophages beta tox+, omega tox+, and gamma tox- into two attachment sites on the Corynebacterium diphtheriae chromosome
1983 • 49 citations
Diphtheria toxin and its mutant crm 197 differ in their interaction with lipids
1987 • 32 citations
Epidermal growth factor receptor binding is affected by structural determinants in the toxin domain of transforming growth factor-alpha-Pseudomonas exotoxin fusion proteins.
1989 • 30 citations
A C terminus cysteine of diphtheria toxin B chain involved in immunotoxin cell penetration and cytotoxicity.
1988 • 14 citations