Inhibition of Ribosomal Ribonucleic Acid Maturation in Rat Liver by 5-Fluoroorotic Acid Resulting in the Selective Labeling of Cytoplasmic Messenger Ribonucleic Acid

Resolution of Multiple Ribonucleic Acid Species by Polyacrylamide Gel Electrophoresis^*

1967 • 866 citations

Electrophoretic separation of viral nucleic acids on polyacrylamide gels

1967 • 770 citations

Ribosomal Aggregate Engaged in Protein Synthesis: Characterization of the Ergosome

1963 • 742 citations

Molecular weights of ribosomal RNA in relation to evolution

1968 • 613 citations

Localization and kinetics of formation of nuclear heterodisperse RNA, cytoplasmic heterodisperse RNA and polyribosome-associated messenger RNA in HeLa cells

1968 • 572 citations

Characterization of Macromolecules by Constant Velocity Sedimentation

1967 • 449 citations

Messenger RNA-protein complexes and newly synthesized ribosomal subunits: Analysis of free particles and components of polyribosomes

1968 • 416 citations

THE DETERMINATION OF DENSITY DISTRIBUTIONS AND DENSITY GRADIENTS IN BINARY SOLUTIONS AT EQUILIBRIUM IN THE ULTRACENTRIFUGE¹

1961 • 399 citations

The Second Sir Hans Krebs Lecture

2005 • 397 citations

Diversity of RNA Components in Green Plant Tissues

1967 • 305 citations

Structure and Synthesis of Ribosomal RNA

1970 • 289 citations

REVERSAL OF MUTANT PHENOTYPES BY 5-FLUOROURACID: AN APPROACH TO NUCLEOTIDE SEQUENCES IN MESSENGER-RNA

1962 • 280 citations

The roles of inducer and catabolite repressor in the synthesis of β-galactosidase by Escherichia coli

1964 • 277 citations

Fluorinated Pyrimidines

1965 • 252 citations

A PARADOXICAL EFFECT OF ACTINOMYCIN D: THE MECHANISM OF REGULATION OF ENZYME SYNTHESIS BY HYDROCORTISONE

1964 • 249 citations

Studies on fluorinated pyrimidines. III. The metabolism of 5-fluorouracil-2-C14 and 5-fluoroorotic-2-C14 acid in vivo.

1958 • 247 citations

Biosynthesis of Messenger and Ribosomal Ribonucleic Acids in the Nucleolochromosomal Apparatus of Animal Cells

1963 • 238 citations

Processing of 45 s nucleolar RNA

1970 • 234 citations

Acrylamide gel electrophoresis of HeLa cell nucleolar RNA.

1967 • 221 citations

Messenger RNA in rat liver polyribosomes: Evidence that it exists as ribonucleoprotein particles

1968 • 220 citations

A SURVEY OF THE METABOLISM OF OROTIC ACID IN THE RAT

1952 • 189 citations

Messenger RNA in HeLa Cells:

1970 • 171 citations

Studies on the Induction and Repression of Enzymes in Rat Liver

1964 • 155 citations

Rapid equilibrium isopycnic CsCl gradients

1969 • 145 citations

"Superinduction" of tyrosine transaminase in hepatoma cell cultures: differential inhibition of synthesis and turnover by actionomycin D.

1968 • 128 citations

The Incorporation of 5-Fluorouracil Into RNA and its Molecular Consequences

1969 • 117 citations

Selective inhibition of ribosomal RNA synthesis in mammalian cells

1968 • 102 citations

Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells

1970 • 102 citations

Ribonucleic Acid Maturation in animal Cells

1971 • 96 citations

Rapidly Labeled Messenger Ribonucleic Acid-Protein Complex of Rat Liver Nuclei

1968 • 65 citations

Characterization of Protein Bound to Rapidly‐Labelled RNA in Polyribosomes from Rat Liver

1970 • 65 citations

Intermediary steps of ribosome formation in Escherichia coli

1964 • 61 citations

Miscoding caused by 5-fluorouracil

1969 • 58 citations

Modification by 8-Azaguanine of the Effects of Hydrocortisone on the Induction and Inactivation of Tyrosine Transaminase of Rat Liver

1969 • 44 citations

Pulse-labeled ribonucleic acid complexes released by dissociation of rat liver polysomes

1971 • 42 citations

Ribosome Synthesis in Escherichia coli Treated with 5-Fluorouracil^*

1966 • 30 citations

Characteristics of 5-fluorouracil-induced synthesis of alkaline phosphatase

1965 • 30 citations

Polyacrylamide-Agarose Electrophoretic Pattern of the RNA Labelling in Liver Cytoplasm and Total Liver of 5-Fluorouracil Treated Rats

1970 • 25 citations

The effect of pyrimidine analogues and tryptophan on enzyme synthesis and degradation in rat liver

1971 • 24 citations

Cytological, radioautographic and ultrastructural studies on the effect of 5-fluorouracil on rat liver.

1966 • 23 citations

RNA synthesis in the liver of rats treated with 5-fluorouracil

1967 • 22 citations

Cytological, radioautographic and ultrastructural studies on the effect of 5-fluorouracil on rat liver

1966 • 22 citations

Some effects of 5-fluoroorotic acid and 5-fluorouracii, on the soluble ribonucleic acid of rat liver

1962 • 16 citations

Comparative effects of actinomycin and ionizing radiation on enzyme synthesis in mammalian cells in vivo.

1968 • 16 citations

Comparative Effects of Actinomycin and Ionizing Radiation on Enzyme Synthesis in Mammalian Cells in Vivo

1968 • 15 citations

Incorporation of label from 5‐fluoroorotate into non‐ribosomal cytoplasmic RNA in rat liver

1970 • 15 citations

Ribonucleoprotein complexes containing messenger ribonucleic acid from rat liver polyribosomes: Analysis of conditions of their appearance after diaminoethane tetra-acetic acid treatment of polyribosomes

1970 • 10 citations

Radioautographic, ultrastructural and biochemical studies on the effect of fluorouracil on the RNA synthesis in the liver of rats

1967 • 9 citations

Inhibitory mechanism of 5-fluoroorotate action in rat liver

1971 • 3 citations