The Molecular Variations of Cytochrome c as a Function of the Evolution of Species1

Construction of Phylogenetic Trees

1967 • 3,637 citations

Evolutionary Rate at the Molecular Level

1968 • 3,608 citations

A Protein Sequenator

1967 • 2,826 citations

Evolutionary Divergence and Convergence in Proteins

1965 • 2,780 citations

THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION

1964 • 2,659 citations

Non-Darwinian Evolution

1969 • 1,731 citations

Distinguishing Homologous from Analogous Proteins

1970 • 1,512 citations

Stereochemical criteria for polypeptides and proteins. V. Conformation of a system of three linked peptide units

1968 • 1,497 citations

General Nature of the Genetic Code for Proteins

1961 • 1,347 citations

Molecules as documents of evolutionary history

1965 • 1,305 citations

Ferricytochrome c

1971 • 879 citations

THE COVALENT STRUCTURE OF AN ENTIRE γG IMMUNOGLOBULIN MOLECULE

1969 • 869 citations

Regulation of Enzyme Activity

1966 • 612 citations

The structure of cytochromec and the rates of molecular evolution

1971 • 540 citations

On cytochrome, a respiratory pigment, common to animals, yeast, and higher plants

1925 • 533 citations

Protein Polymorphism as a Phase of Molecular Evolution

1971 • 512 citations

An improved method for determining codon variability in a gene and its application to the rate of fixation of mutations in evolution

1970 • 469 citations

PRIMARY STRUCTURE AND EVOLUTION OF CYTOCHROME C

1963 • 419 citations

Evolution of higher-organism DNA

1970 • 328 citations

The Reversible Removal of Cytochrome c from Mitochondria

1960 • 323 citations

On the constancy of the evolutionary rate of cistrons

1971 • 318 citations

An improved method of testing for evolutionary homology

1966 • 313 citations

Comparison of the Amino Acid Sequence of Bovine α-Lactalbumin and Hens Egg White Lysozyme

1967 • 308 citations

THE RATE OF MOLECULAR EVOLUTION CONSIDERED FROM THE STANDPOINT OF POPULATION GENETICS

1969 • 298 citations

Chemical Paleogenetics. Molecular "Restoration Studies" of Extinct Forms of Life.

1963 • 297 citations

Gene Evolution and the Hæmoglobins

1961 • 295 citations

Fitting Discrete Probability Distributions to Evolutionary Events

1971 • 277 citations

Amino-Acid Sequence of Horse Heart Cytochrome C : The Complete Amino-acid Sequence

1961 • 264 citations

THE EVOLUTIONARY ORIGINS OF THE IMMUNOGLOBULINS

1966 • 258 citations

ON THE COLINEARITY OF GENE STRUCTURE AND PROTEIN STRUCTURE

1964 • 254 citations

Studies on Cytochrome c. I. Electrophoretic Purification of Cytochrome c and its Amino Acid Composition^*

1941 • 238 citations

Antibody Active Sites and Immunoglobulin Molecules

1966 • 221 citations

Conformation of ferricytochrome c. IV. Relationship between optical absorption and protein conformation

1967 • 191 citations

Quantitative Immunochemistry and the Evolution of Primate Albumins: Micro-Complement Fixation

1966 • 188 citations

On the rate of molecular evolution

1971 • 185 citations

Comparative Aspects of Primary Structures of Proteins

1968 • 184 citations

Interconversion of Horse Heart Cytochrome c Monomer and Polymers

1962 • 179 citations

Rate of change of concomitantly variable codons

1971 • 176 citations

Oxidation-linked Proton Functions in Heme Octa- and Undecapeptides from Mammalian Cytochrome c

1960 • 167 citations

Pulsed NMR Study of the Structure of Cytochrome c

1972 • 164 citations

Darwinian Evolution of Proteins

1970 • 163 citations

Electrophoretic Behavior of Mammalian-type Cytochromes c

1966 • 162 citations

Complex formation between methionine and a heme peptide from cytochrome c.

1965 • 160 citations

A method for estimating the number of invariant amino acid coding positions in a gene using cytochrome c as a model case

1967 • 156 citations

The Human Hemoglobins: Their Properties and Genetic Control

1957 • 154 citations

Mitochondria metabolite transport

1970 • 147 citations

Location of the Heme in Horse Heart Ferricytochrome c by X-Ray Diffraction

1967 • 143 citations

Non-Darwinian Evolution: A Critique

1970 • 137 citations

Bacterial Cytochromes: I. Structural Aspects

1970 • 133 citations

Human Heart Cytochrome c

1963 • 119 citations

Selective Constraints on Amino-acid Substitutions during the Evolution of Proteins

1970 • 115 citations

HIGH-RESOLUTION PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY OF CYTOCHROME c

1969 • 113 citations

Differential Binding Properties of Cytochrome c: Possible Relevance for Mitochondrial Ion Transport

1970 • 112 citations

Studies on Cytochrome c. IV. The Magnetic Properties of Ferric and Ferrous Cytochrome c

1941 • 112 citations

Cytochrome c2 of Rhodospirillum rubrum

1968 • 110 citations

Ca2+ metabolism in yeast cells and mitochondria

1970 • 107 citations

“Haldane's Dilemma” and the Rate of Evolution

1968 • 103 citations

Structural and Functional Aspects of Cytochrome c in Relation to Evolution

1965 • 103 citations

Proton magnetic resonance evidence for methionine-iron coordination in mammalian-type ferrocytochrome c

1969 • 101 citations

Amino acid free radicals in oxidised metmyoglobin

1967 • 98 citations

On the Stereochemical Structure of Cytochrome c.

1955 • 98 citations

Sequence and structure homologies in bacterial and mammalian-type cytochromes

1971 • 93 citations

Further improvements in the method of testing for evolutionary homology among proteins

1970 • 89 citations

Double Nuclear Magnetic Resonance Observation of Electron Exchange between Ferri- and Ferrocytochrome c

1970 • 88 citations

Oxidation and Energy Conservation by Mitochondria

1971 • 81 citations

Water-soluble cytochromes from a blue-green alga. I. Extraction, purification, and spectral properties of cytochromes C (549, 552, and 554, Anacystis nidulans)

1967 • 81 citations

Electron transfer within and between haemoprotein molecules

1965 • 78 citations

Neurospora crassa Cytochrome c

1966 • 76 citations

Conformational Changes upon Reduction of Cytochrome c

1972 • 76 citations

The complete amino acid sequence in baker's yeast cytochrome c

1963 • 74 citations

EVOLUTIONARY VARIABILITY OF CYTOCHROME C PRIMARY STRUCTURES

1968 • 72 citations

Über die Artspezifität von Cytochromc:Vergleich der Aminosäuresequenz des Thunfisch-Cytochromscmit der des Pferde-Cytochromsc

1963 • 63 citations

Study of a Peptic Degradation Product of Cytochrome c. II. Investigation of the Linkage between Peptide Moiety and Prosthetic Group.

1955 • 62 citations

Reconstitution of Phosphorylating Electron Transport in Mitochondria from a Cytochrome c-deficient Yeast Mutant

1966 • 60 citations

Amino acid sequence studies on artiodactyl fibrinopeptides

1967 • 57 citations

Deleterious Mutations and Neutral Substitutions

1971 • 56 citations

Population Size, Polymorphism, and the Rate of Non-Darwinian Evolution

1970 • 52 citations

LINKED FUNCTIONS IN HEME SYSTEMS: OXIDATION-REDUCTION POTENTIALS AND ABSORPTION SPECTRA OF A HEME PEPTIDE OBTAINED UPON PEPTIC HYDROLYSIS OF CYTOCHROME C

1959 • 50 citations

The nonidentity of invariable positions in the cytochromes c of different species

1971 • 48 citations

RNA SEQUENCE ANALYSIS

1970 • 48 citations

The nitration of cytochrome c

1969 • 46 citations

Comparative Biochemistry of Cytochrome c

1964 • 45 citations

Primary Structure of the Cytochrome c from the Great Grey Kangaroo, Macropus canguru

1966 • 43 citations

Nitrocytochrome c. I. Structure and enzymic properties

1970 • 43 citations

Die C-terminale Aminosäuresequenz des Thunfisch-Cytochromsc

1965 • 42 citations

Non-Darwinian Evolution: Consequences for Neutral Allelic Variation

1969 • 40 citations

Production of a ‘Cytochrome c’ with Myoglobin-like Properties by Alkylating the Cyanide Complex with Bromoacetate

1965 • 39 citations

Polymorphism and protein evolution. The neutral mutation-random drift hypothesis.

1971 • 38 citations

Nitrocytochrome c. II. Spectroscopic properties and chemical reactivity

1970 • 38 citations

A set theoretical approach to immunotaxonomy: Analysis of species comparisons in modified ouchterlony plates

1968 • 37 citations

Cytochrome c and Evolution

1967 • 37 citations

Alkylation of cytochromes c I. Properties of alkylated beef cytochrome c

1966 • 36 citations

Hemoglobins A and A₂in New World Primates: Comparative Variation and Its Evolutionary Implications

1969 • 35 citations

Amino acid sequence of the Fc region of a human gamma G-immunoglobulin.

1968 • 35 citations

The Amino-Acid Sequence of the Cytochrome c of Gikgo biloba L.

1971 • 35 citations

Primary Structure of the Cytochrome c from the Snapping Turtle, Chelydra Serpentina^*

1966 • 35 citations

The amino acid sequence of cytochrome c from Abutilon theophrasti Medic. and Gossypium barbadense L. (cotton)

1971 • 32 citations

CARBOXYMETHYLATION OF THE METHIONINE RESIDUES OF CYTOCHROMEc

1965 • 31 citations

The redox potential of cytochrome c: Ion binding and oxidation state as linked functions

1970 • 28 citations

A Comparison of the Amino Acid Sequences of the Cytochrome c of Several Vertebrates.

1963 • 25 citations

THE AMINO ACID SEQUENCE OF CYTOCHROMEcIN RELATION TO ITS FUNCTION AND EVOLUTION

1964 • 25 citations

Die Aminosäure‐Sequenz vom Cytochrom c des Karpfens, Cyprinus carpio

1970 • 22 citations

The Iron-protein Bonds in Cytochrome c.

1951 • 22 citations

The amino acid sequence of cytochrome c from Cucurbita maxima L. (pumpkin)

1971 • 21 citations

The Amino Acid Sequence of Cytochrome c from Bonito (Katsuwonus pelamis, Linnaeus)

1971 • 19 citations

Primary structure of cytochrome c from the camel, camelus dromedarius

1972 • 17 citations

Biochemical studies in the developing thoracic muscles of the tobacco horn worm IV. Primary structure of cytochrome c

1970 • 17 citations

The amino acid sequence of cytochrome c of Neurospora crassa.

1965 • 16 citations

FERRICYTOCHROME c: II. CHAIN FLEXIBILITY AND A POSSIBLE REDUCTION MECHANISM††Paper (I) in this series is reference 3. This is Contribution No. 4143 from the Norman W. Church Laboratory of Chemical Biology, California Institute of Technology, Pasadena, California 91109.

1972 • 16 citations

Commuting dilations of self-adjoint operators

1965 • 16 citations

“Haldane's Dilemma” and the Rate of Natural Selection

1969 • 15 citations

Primary structure of cytochrome c from the elephant seal, Mirounga leonina

1972 • 15 citations

Nitration of horse heart ferricytochrome C with tetranitromethane

1969 • 13 citations

Peptides from a tryptic digest of baker's yeast cytochrome c

1963 • 13 citations

Estimation and testing goodness-of-fit for some models of codon fixation variability

1970 • 13 citations

FUNCTIONAL LIMITS OF CYTOCHROME c VARIABILITY

1972 • 11 citations

Cascade Chromatography and Automated Multidimensional Fractionation

1971 • 7 citations

Permeability of housefly flight-muscle mitochondria for succinate

1970 • 7 citations

Comparative Structures of Cytochromes c

1963 • 5 citations