Regulation of ACTH Secretion: Variations on a Theme of B

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Two Receptor Systems for Corticosterone in Rat Brain: Microdistribution and Differential Occupation

1985 • 2,530 citations

Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat

1972 • 2,054 citations

Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions

1972 • 1,975 citations

Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

1983 • 1,954 citations

Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

1986 • 1,521 citations

Corticosteroid Inhibition of ACTH Secretion*

1984 • 1,212 citations

The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat

1982 • 1,128 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin

1982 • 958 citations

Structure and Biosynthesis of Pro-Adrenocorticotropin/Endorphin and Related Peptides*

1980 • 859 citations

The Serum Transport of Steroid Hormones

1982 • 777 citations

Responses to Corticotropin-Releasing Hormone in the Hypercortisolism of Depression and Cushing's Disease

1986 • 773 citations

Central Noradrenergic Pathways for the Integration of Hypothalamic Neuroendocrine and Autonomic Responses

1981 • 579 citations

Effects of Synthetic Ovine Corticotropin-Releasing Factor, Glucocorticoids, Catecholamines, Neurohypophysial Peptides, and Other Substances on Cultured Corticotropic Cells*

1983 • 567 citations

Renal mineralocorticoid receptors and hippocampal corticosterone-binding species have identical intrinsic steroid specificity.

1983 • 515 citations

Secretory products of macrophages and their physiological functions

1984 • 494 citations

Co-expression of corticotropin-releasing factor and vasopressin immunoreactivity in parvocellular neurosecretory neurons of the adrenalectomized rat.

1984 • 481 citations

Differences in Corticosterone and Dexamethasone Binding to Rat Brain and Pituitary¹

1975 • 456 citations

Abnormal Hypothalamic–Pituitary–Adrenal Function in Anorexia Nervosa

1986 • 453 citations

Mediation by Corticotropin Releasing Factor (CRF) of Adenohypophysial Hormone Secretion

1986 • 443 citations

Natural History of Pituitary-Adrenal Recovery Following Long-Term Suppression with Corticosteroids1

1965 • 376 citations

Endocrinology and Metabolism.

1988 • 376 citations

Degeneration studies of primary afferents of IXth and Xth cranial nerves in the cat

1964 • 316 citations

Rat Brain Binds Adrenal Steroid Hormone: Radioautography of Hippocampus with Corticosterone

1972 • 309 citations

Corticotropin-releasing factor-immunoreactive neurons of the paraventricular nucleus become vasopressin positive after adrenalectomy.

1984 • 301 citations

Efferent connections of the ventral medulla oblongata in the rat

1981 • 293 citations

Suprachiasmatic Nuclear Lesions Do Not Abolish Food-Shifted Circadian Adrenal and Temperature Rhythmicity

1977 • 292 citations

Co-localization of corticotropin releasing factor and vasopressin mRNA in neurones after adrenalectomy

1985 • 287 citations

Mechanisms of action of corticotropin-releasing factor and other regulators of corticotropin release in rat pituitary cells.

1983 • 275 citations

Effects of Adrenalectomy and Dexamethasone Administration on the Level of Prepro-Corticotropin-Releasing Factor Messenger Ribonucleic Acid (mRNA) in the Hypothalamus and Adrenocorticotropin/β-Lipotropin Precursor mRNA in the Pituitary in Rats*

1985 • 274 citations

Virus-Induced Corticosterone in Hypophysectomized Mice: A Possible Lymphoid Adrenal Axis

1982 • 266 citations

Hemorrhage-Induced Secretion of Corticotropin-Releasing Factor-Like Immunoreactivity into the Rat Hypophysial Portal Circulation and Its Inhibition by Glucocorticoids*

1984 • 260 citations

The role of the solitary and paramedian reticular nuclei in mediating cardiovascular reflex responses from carotid baro‐ and chemoreceptors

1972 • 257 citations

Potentiation by Vasopressin of Corticotropin Release Induced by Corticotropin-Releasing Factor1

1971 • 247 citations

Distribution of carotid sinus and depressor nerves in cat brain stem

1968 • 244 citations

The Responses of Plasma Adrenocorticotropin and Cortisol to Corticotropin-Releasing Hormone (CRH) and Cerebrospinal Fluid Immunoreactive CRH in Anorexia Nervosa Patients*

1986 • 241 citations

Corticosteroid Feedback Control of ACTH Secretion: Effect of Stress-Induced Corticosterone Secretion on Subsequent Stress Responses in the Rat1

1973 • 237 citations

The New Steroid Analog RU 486 Inhibits Glucocorticoid Action in Man

1984 • 234 citations

Co-localization of corticotropin-releasing factor and vasopressin in median eminence neurosecretory vesicles

1985 • 231 citations

Diurnal Cortisol Peaks and Their Relationships to Meals

1982 • 226 citations

Diurnal Variation in Suppression of Adrenal Function by Glucocorticoids

1965 • 221 citations

Glucocorticoid regulation of pro-opiomelanocortin gene transcription in the rat pituitary.

1984 • 218 citations

RU 486: a steroid with antiglucocorticosteroid activity that only disinhibits the human pituitary-adrenal system at a specific time of day.

1984 • 216 citations

Steroid hormone receptors : structure and function

1983 • 210 citations

Projections of the carotid sinus nerve to the nucleus of the solitary tract in the cat

1980 • 210 citations

Glucocorticoids regulate proopiomelanocortin gene expression in vivo at the levels of transcription and secretion.

1983 • 199 citations

An autoradiographic determination of the efferent projections of the suprachiasmatic nucleus of the hypothalamus

1981 • 193 citations

Subcutaneous implantation method for chronic glucocorticoid replacement therapy

1979 • 189 citations

Characterization of Rat Brain Aldosterone Receptors Reveals High Affinity for Corticosterone

1983 • 188 citations

Evidence for a specific mineralocorticoid receptor in rat pituitary and brain

1980 • 187 citations

Effects of Destruction of the Suprachiasmatic Nuclei on the Circadian Rhythms in Plasma Corticosterone, Body Temperature, Feeding and Plasma Thyrotropin

1979 • 185 citations

EFFECTS OF LESIONS OF THE SUPRACHIASMATIC NUCLEI AND OF p-CHLOROPHENYLALANINE ON THE CIRCADIAN RHYTHMS OF ADRENOCORTICOTROPHIC HORMONE AND CORTICOSTERONE IN THE PLASMA, AND ON LOCOMOTOR ACTIVITY OF RATS

1979 • 179 citations

Chronic Administration of Corticotropin-Releasing Factor Increases Pituitary Corticotroph Number*

1987 • 178 citations

Glucocorticoid Receptors in Rat Kidney: The Rinding of Tritiated-Dexamethasone1

1973 • 173 citations

Corticosteroid-Binding Globulin in the Rat: Studies on the Sex Difference

1965 • 172 citations

Glucocorticoid sensitivity of vasopressin mRNA levels in the paraventricular nucleus of the rat.

1986 • 165 citations

Glucocorticoid Implants around the Hypothalamic Paraventricular Nucleus Prevent the Increase of Corticotropin-Releasing Factor and Arginine Vasopressin Immunostaining Induced by Adrenalectomy

1986 • 164 citations

Plasma corticosterone concentrations sensitively reflect levels of stimulus intensity in the rat

1979 • 163 citations

Regulation of Glucocorticoid Receptors in Brain by Corticosterone Treatment of Adrenalectomized Rats

1982 • 159 citations

Characterization of corticotropin receptors on adrenocortical cells.

1981 • 156 citations

Late-Onset 21-Hydroxylase Deficiency Mimicking Idiopathic Hirsutism or Polycystic Ovarian Disease

1982 • 154 citations

Regulation of Corticotropin-Releasing Factor (CRF) Receptors in the Rat Pituitary Gland: Effects of Adrenalectomy on CRF Receptors and Corticotroph Responses

1985 • 154 citations

Adrenergic innervation of corticotropin releasing factor (CRF) ? synthesizing neurons in the hypothalamic paraventricular nucleus of the rat

1986 • 152 citations

Effect of Paraventricular Lesions on Corticotropin-Releasing Factor (CRF)-Like Immunoreactivity in the Stalk-Median Eminence: Studies on the Adrenocorticotropin Response to Ether Stress and Exogenous CRF*

1984 • 151 citations

THE ADRENOCORTICAL RESPONSE TO INSULIN-INDUCED HYPOGLYCAEMIA

1963 • 143 citations

Evidence for Multifactor Regulation of the Adrenocorticotropin Secretory Response to Hemodynamic Stimuli*

1985 • 142 citations

Steroid hormone target sites in the brain: The differential distribution of estrogen, progestin, androgen and glucocorticosteroid

1976 • 142 citations

A MID-DAY SURGE IN CORTISOL LEVELS

1979 • 136 citations

Evidence for a Role of the Supraopticohypophyseal System in Regulation of Adrenocorticotropic Secretion

1954 • 136 citations

The Effects of Adrenalectomy and Glucocorticoid Replacement on Vasopressin and Vasopressin-Neurophysin in the Zona Externa of the Median Eminence of the Rat

1977 • 132 citations

VASOPRESSIN POTENTIATES CYCLIC AMP ACCUMULATION AND ACTH RELEASE INDUCED BY CORTICOTROPIN-RELEASING FACTOR (CRF) IN RAT ANTERIOR PITUITARY CELLS IN CULTURE

1982 • 128 citations

Tonic force maintenance with reduced shortening velocity in arterial smooth muscle

1982 • 123 citations

Morphometrical analysis of the distribution of corticotrophin releasing factor, glucocorticoid receptor and phenylethanolamine-N-methyltransferase immunoreactive structures in the paraventricular hypothalamic nucleus of the rat

1985 • 122 citations

Inhibition of Immunoreactive Corticotropin-Releasing Factor Secretion into the Hypophysial-Portal Circulation by Delayed Glucocorticoid Feedback*

1986 • 118 citations

Control of Adrenocortical Growth in Vivo

1984 • 116 citations

Radioautographic study of the rat brain after injection of [1,2-3H]corticosterone

1975 • 112 citations

Reset of Feedback in the Adrenocortical System: An Apparent Shift in Sensitivity of Adrenocorticotropin to Inhibition by Corticosterone between Morning and Evening*

1986 • 111 citations

The ‘suprachiasmatic syndrome’: endocrine and behavioural abnormalities following lesions of the suprachiasmatic nuclei in the female rat

1977 • 110 citations

Corticosteroid Feedback Control of ACTH Secretion: Rapid Effects of Bilateral Adrenalectomy on Plasma ACTH in the Rat1

1972 • 106 citations

Plasma Corticosterone Response to Environmental Stimulation: Effects of Duration of Stimulation and the 24-Hour Adrenocortical Rhythm

1968 • 106 citations

A putative glucocorticoid receptor and a transcortin-like macromolecule in pituitary cytosol

1976 • 103 citations

Quantification of Morphological Changes in Pituitary Corticotropes Produced byin VivoCorticotropin-Releasing Factor Stimulation and Adrenalectomy*

1985 • 103 citations

Electron microscopic analysis of tyrosine hydroxylase, dopamine-?-hydroxylase and phenylethanolamine-N-methyltransferase immunoreactive innervation of the hypothalamic paraventricular nucleus in the rat

1986 • 102 citations

Corticotrope Response to Removal of Releasing Factors and Corticosteroids in Vivo*

1985 • 100 citations

Influence of Water Deprivation on Adrenocortical Rhythms

1973 • 99 citations

Circadian Patterns of Stress-Induced ACTH Secretion Are Modified by Corticosterone Responses

1977 • 97 citations

VASOPRESSIN AND CORTICOTROPIN‐RELEASING FACTOR: AN AXONAL PATHWAY TO PORTAL CAPILLARIES IN THE ZONA EXTERNA OF THE MEDIAN EMINENCE CONTAINING VASOPRESSIN AND ITS INTERACTION WITH ADRENAL CORTICOIDS*

1977 • 96 citations

Return of Pituitary-Adrenal Function after Adrenal Enucleation or Transplantation: Diurnal Rhythms and Responses to Ether*

1981 • 95 citations

Diminishing Corticotrope Capacity to Release ACTH During Sustained Stimulation: The Twenty-four Hours After Bilateral Adrenalectomy in the Rat¹

1974 • 95 citations

Selective reduction of proadrenocorticotropin/endorphin proteins and messenger ribonucleic acid activity in mouse pituitary tumor cells by glucocorticoids

1979 • 94 citations

Control Processes in Multicellular Organisms.

1971 • 90 citations

Brain-pituitary-adrenal interrelationships

1975 • 88 citations

Diurnal Variation in the Response of Plasma Adrenocorticotropin and Cortisol to Intravenous Ovine Corticotropin-Releasing Hormone*

1985 • 82 citations

Radioautographic study of the rat brain and pituitary after injection of 3H dexamethasone

1975 • 80 citations

The Effects of Intracerebroventricular Administration of Renin on Drinking and Blood Pressure¹

1975 • 79 citations

Corticotropin Releasing Factor (CRF): Origin and Course of Afferent Pathways to the Median Eminence (ME) of the Rat Hypothalamus

1984 • 78 citations

Corticosterone-Induced Changes in Hypothalamic Corticotropin-Releasing Factor (CRF) Content After Stress¹

1975 • 77 citations

Specific Receptors for Vasopressin in the Pituitary Gland: Evidence for Down-Regulation and Desensitization to Adrenocorticotropin-Releasing Factors

1985 • 76 citations

Phorbol ester inhibition of Na-H exchange in rabbit proximal colon

1985 • 74 citations

Comparison of the Effects of 2-Deoxyglucose and Immobilization on Plasma Levels of Catecholamines and Corticosterone in Awake Rats

1979 • 71 citations

Neural Control of ACTH: A Homeostatic Reflex

1978 • 70 citations

EFFECTS OF BILATERAL ADRENALECTOMY ON IMMUNOREACTIVE CORTICOTROPIN-RELEASING FACTOR IN THE RAT MEDIAN EMINENCE AND INTERMEDIATE-POSTERIOR PITUITARY

1983 • 70 citations

Predominant Release of Vasopressin vs. Corticotropin-Releasing Factor from the Isolated Median Eminence after Adrenalectomy

1986 • 67 citations

Localization and role of transcortin-like molecules in the anterior pituitary

1977 • 66 citations

Biphasic Inhibition of Adrenocorticotropin Release by Corticosterone in Cultured Anterior Pituitary Cells

1986 • 66 citations

Characterization of an Early Inhibitory Effect of Glucocorticoids on Stimulated Adrenocorticotropin and Endorphin Release from a Clonal Strain of Mouse Pituitary Cells*

1982 • 65 citations

Diurnal Variations in Responsiveness of the Hypothalamo-Pituitary-Adrenocortical Axis of the Rat

1985 • 63 citations

Direct stimulation of beta 2-adrenergic receptors in rat anterior pituitary induces the release of adrenocorticotropin in vivo.

1983 • 61 citations

β-Adrenergic Mechanism of Insulin-Induced Adrenocorticotropin Release from the Anterior Pituitary

1984 • 60 citations

Adrenocortical Responses following Limbic Stimulation in Rats with Hypothalamic Deafferentations

1982 • 60 citations

Effects of cortisol implants in the brainstem and ventral hippocampus on diurnal corticosteroid levels

1966 • 58 citations

Regulation of the Adrenocortical Response to Insulin-Induced Hypoglycemia*

1982 • 57 citations

Insulin-Induced Hypoglycemia in Conscious Dogs. I. Dose-Related Pituitary and Adrenal Responses*

1981 • 56 citations

Amygdalar Participation in Tonic ACTH Secretion in the Rat

1975 • 56 citations

Autoradiographic studies of 3H-dexamethasone uptake by immunocytochemically characterized cells of the rat pituitary

1977 • 56 citations

Control of Release of Adrenocorticotropin and Vasopressin by the Supraoptic and Paraventricular Nuclei*

1981 • 55 citations

Inhibition of the Adrenocorticotropin and Corticosteroid Responses to Hypoglycemia after Prior Stress*

1983 • 55 citations

Adrenocorticotropic Regulations after Bilateral Lesions of the Paraventricular or Supraoptic Nuclei and in Brattleboro Rats

1982 • 54 citations

Right and left atrial B-fiber input to the medulla of the cat

1975 • 54 citations

Structure-activity relationship and the mode of action of corticosteroid feedback on the secretion of corticotrophin-releasing factor (corticoliberin)

1976 • 53 citations

Comparison of Effects of Adrenocorticotropin and Lys-γ₃Melanocyte-Stimulating Hormone on Steroidogenesis, Adenosine 3′,5′-Monophosphate Production, and Phospholipid Metabolism in Rat Adrenal Fasciculata-Reticularis Cells in Vitro*

1983 • 50 citations

PLASMA ADRENOCORTICOTROPIN AND CORTISOL RESPONSES TO INTRAVENOUS INJECTION OF CORTICOTROPINRELEASING FACTOR IN THE MORNING AND EVENING

1983 • 49 citations

Interactions between CRF, epinephrine, vasopressin and glucocorticoids in the control of acth secretion

1984 • 48 citations

Adrenocortical Sensitivity to Adrenocorticotropin (ACTH) in Awake Dogs Changes as a Function of the Time of Observation and after Hemorrhage Independently of Changes in ACTH

1981 • 48 citations

Effect of Synthetic Vasopressin on Release of Adrenocorticotrophin in Rats with Hypothalamic Lesions.

1957 • 47 citations

Measurement of hormones and blood gases during hypoxia in conscious cannulated rats

1984 • 47 citations

Norepinephrine depletion in the paraventricular nucleus inhibits the adrenocortical responses to neural stimuli

1986 • 47 citations

The Concentration of Arginine Vasopressin in Pituitary Stalk Plasma of the Rat after Adrenalectomy or Morphine^*

1986 • 45 citations

AFFERENT PATHWAYS OF STRESSFUL STIMULI: CORTICOTROPHIN RELEASE AFTER HYPOTHALAMIC DEAFFERENTATION

1970 • 44 citations

Temporal Variation in Su-4885 Responsiveness in Man: Evidence in Support of Circadian Variation in ACTH Secretion

1964 • 41 citations

EFFECT OF BILATERAL ADRENALECTOMY AND CORTICOSTEROID THERAPY ON THE SECRETION OF CORTICOTROPHIN-RELEASING FACTOR ACTIVITY FROM THE HYPOTHALAMUS OF THE RAT IN VITRO

1976 • 40 citations

The autoradiographic localization of [3H]dexamethasone in the brain and pituitary of the rat

1975 • 40 citations

Immunoreactive γ-Melanotropin in Rat Pituitary and Plasma: A Partial Characterization*

1982 • 39 citations

Pituitary Binding of Vasopressin Is Altered by Experimental Manipulations of the Hypothalamo-Pituitary-Adrenocortical Axis in Normal as well as Homozygous (di/di) Brattleboro Rats*

1985 • 38 citations

Role of atrial receptors in the control of ACTH

1976 • 37 citations

Drug-Induced Adrenal Hypertrophy Provides Evidence for Reset in the Adrenocortical System*

1983 • 37 citations

Interaction between angiotensin II and the baroreceptor reflex in the control of adrenocorticotropic hormone secretion and heart rate in conscious dogs.

1986 • 37 citations

Increased Cortisol Secretion after Small Hemorrhage Is Not Attributable to Changes in Adrenocorticotropin^*

1983 • 35 citations

Intracellular CBG-like molecules in the rat pituitary

1984 • 34 citations

Immediate and Delayed Alterations of Adrenocorticotropin and Cortisol Nyctohemeral Profiles after Corticotropin-Releasing Factor in Normal Man*

1983 • 34 citations

ACTH and Corticosterone Secretion in Rats following Removal of the Neurointermediate Lobe of the Pituitary Gland

1985 • 34 citations

Effect of steroid competition and time on the uptake of [3H]corticosterone in the rat brain; An autoradiographic study

1975 • 34 citations

Corticotrophin Release Induced byE. coliEndotoxin After Removal of the Medial Hypothalamus

1971 • 34 citations

Electrically Stimulated ACTH Release in Pharmacologically Blocked Rats1

1973 • 32 citations

THE ROLE OF THE MEDIAL FOREBRAIN BUNDLE IN MEDIATING ADRENOCORTICAL RESPONSES TO NEUROGENIC STIMULI

1971 • 32 citations

Insulin-Induced Hypoglycemia in Conscious Dogs: Effect of Maintaining Carotid Arterial Glucose Levels on the Adrenocorticotropin, Epinephrine, and Vasopressin Responses*

1983 • 30 citations

Corticosteroid Feedback Control of Stress-Induced ACTH Secretion1

2015 • 27 citations

Relationship between ACTH Secretion and Corticoid Binding to Specific Receptors in Perifused Adenohypophyses

1979 • 26 citations

Tooth Pulp Stimulation Potentiates the Adrenocorticotropin Response to Hemorrhage in Cats*

1982 • 26 citations

Hypothalamic cells in an area mediating ACTH release respond to right atrial stretch

1975 • 25 citations

Carotid vascular receptors and control of adrenal corticosteroid secretion

1966 • 24 citations

Inhibitory and Facilitatory Areas of the Dorsal Medulla Mediating ACTH Release in the Cat

1976 • 23 citations

Feedback Inhibition of Adrenocorticotropin and Vasopressin Responses to Hypoxia by Physiological Increases in Endogenous Plasma Corticosteroids in Dogs*

1984 • 22 citations

Relationship Between the Pituitary Gland and the Corticosteroid-Binding Globulin in the Rat

1966 • 22 citations

Plasma Catecholamines Do Not Participate in Pituitary-Adrenal Activation by Immobilization Stress in Rats with Transection of Nerve Fibers to the Median Eminence

1986 • 21 citations

Alterations in local cerebral glucose utilization (LCGU) in rat brain during hypoxemia.

1979 • 21 citations

Feedback inhibition of adrenocorticotropic hormone by physiological increases in plasma corticosteroids in conscious dogs.

1983 • 21 citations

Role of prostaglandin release in the response of tight epithelia to Ca2+ ionophores

1986 • 21 citations

A quantitative approach to trace the corticotrophs in culture after adrenalectomy

1981 • 21 citations

In vitro Release of Vasopressin and Oxytocin from Rat Median Eminence Tissue

1986 • 20 citations

Inhibition by corticosterone of paraventricular nucleus multiple-unit activity responses to sensory stimuli in freely moving rats

1986 • 19 citations

Negative feedback in adrenocortical response to limbic stimulation in Macaca mulatta

1967 • 19 citations

The Importance of the Hypothalamic Lateral Retrochiasmatic Area in the Control of Adrenocorticotropin and Thyrotropin Secretion*

1982 • 16 citations

Evidence for two cellular sodium compartments in suspensions of smooth muscle cells

1986 • 15 citations

Adrenocortical responses to ether stress and neural stimuli in rats following the injection of 6-hydroxydopamine into the medial forebrain bundle

1984 • 13 citations

Location of vagal receptors controlling adrenal corticosteroid secretion

1973 • 12 citations

Rate of Blood Glucose Fall as a Determinant Factor in Insulin-Induced Adrenocortical Stimulation

1966 • 12 citations

Electrolytic Lesions of the Dorsal Rostral Pons Prevent Adrenocorticotropin Increases after Hemorrhage*

1984 • 10 citations

Neuroendocrine correlates of stress

1986 • 5 citations

Responsiveness of Adenohypophysial Corticotrophs to Hypothalamic (SME) Extract Remains Unchanged in Rats with Hypothalamic Lesions Inhibiting CRF Release

1983 • 3 citations

The Lack of Effect of Electrochemical Stimulation of the Hypothalamus and Median Eminence on the Plasma Corticosterone Level after Lesion of the Paraventricular Nuclei

2009 • 3 citations