Growth of Cultured Cells Using Collagen as Substrate

Role of cell shape in growth control

1978 • 2,434 citations

Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro.

1979 • 2,025 citations

COLLAGEN SUBSTRATA FOR STUDIES ON CELL BEHAVIOR

1972 • 1,530 citations

Role of collagenous matrices in the adhesion and growth of cells.

1981 • 1,375 citations

Osteonectin, a bone-specific protein linking mineral to collagen

1981 • 1,131 citations

Structurally Distinct Collagen Types

1980 • 1,078 citations

Fibroblast traction as a mechanism for collagen morphogenesis

1981 • 862 citations

Reconstituted rattail collagen used as substrate for tissue cultures on coverslips in Maximow slides and roller tubes.

1958 • 660 citations

Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes

1977 • 641 citations

Anchorage and growth regulation in normal and virus‐transformed cells

1968 • 547 citations

Attachment of smooth muscle cells to collagen and their migration toward platelet-derived growth factor.

1981 • 506 citations

Determination of cellular shape by the extracellular matrix and its correlation with the control of cellular growth.

1978 • 487 citations

Topoinhibition and Serum Requirement of Transformed and Untransformed Cells

1970 • 444 citations

The influence of collagen on the development of muscle clones.

1966 • 436 citations

The Growth of Cells on a Transparent Gel of Reconstituted Rat-Tail Collagen<xref ref-type="fn" rid="fn1">2</xref>

1956 • 422 citations

The stimulation of epidermal proliferation by a specific protein (EGF)

1965 • 421 citations

Connective tissue biomatrix: its isolation and utilization for long-term cultures of normal rat hepatocytes.

1980 • 395 citations

Cell proliferation and migration on collagen substrata in vitro

1980 • 347 citations

Growth of normal human mammary cells in culture

1980 • 316 citations

Influence of collagen gel on the orientation of epithelial cell polarity: follicle formation from isolated thyroid cells and from preformed monolayers.

1981 • 296 citations

Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes.

1977 • 292 citations

Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels.

1979 • 285 citations

Morphogenetic Interaction between Embryonic Mouse Tissues separated by a Membrane Filter

1953 • 285 citations

Extracellular matrix promotes mammary epithelial growth and differentiation in vitro.

1982 • 262 citations

Stimulation of clonal growth of normal fibroblasts with substrata coated with basic polymers.

1976 • 254 citations

Contact guidance in vitro

1979 • 245 citations

Isolation and Growth of Adult Human Epidermal Keratinocytes in Cell Culture

1978 • 245 citations

Epidermal cells adhere preferentially to type IV (basement membrane) collagen.

1979 • 240 citations

Primary culture of capillary endothelium from rat brain

1981 • 234 citations

Hormonal control of human colon carcinoma cell growth in serum-free medium.

1980 • 219 citations

Epithelio‐mesenchymal specificity in the morphogenesis of mouse sub‐mandibular rudiments in vitro

1953 • 216 citations

The Differentiated State of Normal and Malignant Cells or How to Define a “Normal” Cell in Culture

1981 • 208 citations

Contraction and organization of collagen gels by cells cultured from periodontal ligament, gingiva and bone suggest functional differences between cell types

1981 • 193 citations

Evidence that contact with connective tissue matrix is required for normal interaction between Schwann cells and nerve fibers.

1978 • 190 citations

Substrate properties influencing ultrastructural differentiation of mammary epithelial cells in culture

1979 • 181 citations

Different mechanisms in the attachment of cells to native and denatured collagen

1979 • 173 citations

Influence of geometry on control of cell growth

1975 • 169 citations

Differential response to growth factor by rat mammary epithelium plated on different collagen substrata in serum-free medium.

1981 • 167 citations

Basement membrane collagen requirements for attachment and growth of mammary epithelium

1979 • 166 citations

Role of collagen and fibronectin in neural crest cell adhesion and migration

1981 • 166 citations

Sustained growth in primary culture of normal mammary epithelial cells embedded in collagen gels

1980 • 165 citations

Growth of Postembryonic Skin Epithelial Cells on Collagen Gels

1971 • 156 citations

Growth Factor- and Cyclic Nucleotide-Induced Proliferation of Normal and Malignant Mammary Epithelial Cells in Primary Culture*

1980 • 145 citations

Contact guidance on oriented collagen gels

1978 • 142 citations

A Sponge Matrix Method for Tissue Culture. Formation of Organized Aggregates of Cells <italic>in Vitro</italic><xref ref-type="fn" rid="fn1">²</xref>

1951 • 142 citations

Preparation of pure neuronal and non-neuronal cultures from embryonic chick sympathetic ganglia: A new method based on both differential cell adhesiveness and the formation of homotypic neuronal aggregates

1976 • 132 citations

Cultured sympathetic neurons: Effects of cell-derived and synthetic substrata on survival and development

1980 • 124 citations

Serum-free growth of normal and tumor mouse mammary epithelial cells in primary culture.

1982 • 118 citations

The influence of cell shape on the induction of functional differentiation in mouse mammary cells in vitro

1981 • 113 citations

Neuronal stimulation of [3H]thymidine incorporation by primary cultures of highly purified non-neuronal cells

1976 • 111 citations

Hormonal requirements for basement membrane collagen deposition by cultured rat mammary epithelium.

1979 • 110 citations

Clonal proliferation of cultured nonmalignant and malignant human breast epithelia.

1981 • 108 citations

Fibroblast adhesion on collagen substrata in the presence and absence of plasma fibronectin

1981 • 103 citations

Collagen required for proliferation of cultured connective tissue cells but not their transformed counterparts

1978 • 102 citations

Do plasma and serum have different abilities to promote cell growth?

1980 • 102 citations

SUBSTRATE AND NUTRIENT EFFECTS UPON EPIDERMAL BASAL CELL ORIENTATION AND PROLIFERATION

1964 • 100 citations

Secretory function of lactating mouse mammary epithelial cells cultured on collagen gels

1980 • 99 citations

The use of three‐dimensional collagen gels for the study of tumour cell invasion in vitro: Experimental parameters influencing cell migration into the gel matrix

1982 • 94 citations

Cytodifferentiation and embryogenesis in cell colonies and tissue cultures derived from ova and blastocysts of the rabbit

1966 • 94 citations

The effects of fibronectin on the migration of human foreskin fibroblasts and syrian hamster melanoma cells into three-dimensional gels of native collagen fibres

1981 • 88 citations

Photo-reconstituted collagen gel for tissue culture substrates

1973 • 84 citations

Effects of hormones and growth factors on human mammary epithelial cells in collagen gel culture.

1981 • 84 citations

Mouse mammary epithelial cells on floating collagen gels: Transepithelial ion transport and effects of prolactin

1979 • 80 citations

Separation of neuronal and nonneuronal cells in monolayer cultures from chick embryo optic lobe

1979 • 77 citations

Influence of Seeding Density on Multicellular Organization and Nuclear Events in Cultures of Normal and Neoplastic Mouse Mammary Epithelium2

1974 • 76 citations

Morphogenesis of branching tubules in cultures of cloned mammary epithelial cells

1980 • 75 citations

Primary Culture of Human Mammary Epithelial Cells Embedded in Collagen Gels&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;

1980 • 73 citations

The influence of the substratum on mesenchyme spreading in vitro

1979 • 72 citations

Importance of a collagen substratum for stimulation of capillary endothelial cell proliferation by tumour angiogenesis factor

1979 • 70 citations

Long-term growth of chicken fibroblasts on a collagen substrate

1974 • 68 citations

Collagen-Coated Cellulose Sponge: Three-Dimensional Matrix for Tissue Culture of Walker Tumor 256

1967 • 68 citations

Growth and Differentiation of Transplanted Epithelial Cell Cultures*

1968 • 62 citations

Growth of human mammary epithelial cells on collagen gel surfaces.

1981 • 59 citations

Glucocorticoid Regulation of Prolactin Receptors on Mammary Cells in Culture*

1979 • 59 citations

Growth of mouse mammary gland end buds cultured in a collagen gel matrix

1982 • 55 citations

Use of collagen-hydroxyethylmethacrylate hydrogels for cell growth.

1980 • 52 citations

Patterns of three-dimensional growth in vitro in collagen-coated cellulose sponge: carcinomas and embryonic tissues.

1968 • 51 citations

Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production.

1981 • 50 citations

Invasion of endothelial cell monolayers on collagen gels by cells from mammary tumor spheroids.

1980 • 48 citations

Stimulation of non-neuronal cell proliferation in vitro by mitogenic factors present in highly purified sympathetic neurons

1978 • 48 citations

Growth in primary culture of mouse submandibular epithelial cells embedded in collagen gels

1982 • 48 citations

Attachment of smooth muscle cells to collagen and their migration toward platelet-derived growth factor

1981 • 47 citations

The cultivation of human embryonic liver cells

1962 • 47 citations

Endothelial cell culture on fibrillar collagen: model to study platelet adhesion and liposome targeting to intercellular collagen matrix.

1981 • 44 citations

Three-dimensional growth and morphogenesis of mouse submandibular epithelial cells in serum-free primary culture

1982 • 43 citations

Explant culture of rat liver. I. Method, morphology, and cytogenesis.

1970 • 40 citations

An estrogen responsive primary amphibian liver cell culture system

1978 • 38 citations

Stimulation by a low-molecular-weight angiogenic factor of capillary endothelial cells in culture

1980 • 38 citations

Collagen gels as a matrix for haemopoiesis

1981 • 38 citations

Scanning and transmission electron microscopy study of a human breast carcinoma cell line (MCF-7) cultured in collagen-coated cellulose sponge.

1977 • 37 citations

Cell shape-mediated growth control of lens epithelial cells grown in culture

1981 • 37 citations

Isolation and Serial Cultivation of Rabbit Skin Epithelial Cells

1978 • 37 citations

Reexpression of the Original Tumor Pattern by a Human Breast Carcinoma Cell Line (MCF-7) in Sponge Culture 2

1976 • 36 citations

The growth and differentiation of transitional epithelium in vitro.

1979 • 36 citations

Serum-free primary culture of human normal mammary epithelial cells in collagen gel matrix

1982 • 35 citations

Growth and Differentiation of Primary Cultures of Mouse Mammary Epithelium Embedded in Collagen Gel

1982 • 35 citations

Neoplastic transformation of rat mammary cells exposed to 7,12-dimethylbenz[alpha]anthracene or N-nitrosomethylurea in cell culture.

1978 • 35 citations

Prolactin effects on ion transport across cultured mouse mammary epithelium

1981 • 28 citations

Transplantation of mouse mammary epithelial cells grown in primary collagen gel cultures.

1982 • 27 citations

Primary culture of mouse mammary tumor epithelial cells embedded in collagen gels

1980 • 27 citations

Simultaneous production of casein and mammary tumor virus in mouse mammary epithelial cells grown on floating collagen gels

1979 • 26 citations

Regulation of mammary tumor virus production by prolactin in BALB/cfC3H mouse normal mammary epithelial cells in vitro.

1977 • 26 citations

A note on growth patterns of epithelial tumor cells in primary culture.

1974 • 24 citations

Growth of preneoplastic mammary epithelial cells in serum-free medium.

1980 • 22 citations

Effect of Collagen and Acid Polysaccharides on the Growth of BHK/21 Cells in Semi-solid Media

1970 • 22 citations

Characterization of a variety of standard collagen substrates: Ultrastructure, uniformity, and capacity to bind and promote growth of neurons

1981 • 21 citations

Effect of hormones and EGF on proliferation of rat mammary epithelium enriched for alveoli

1982 • 21 citations

Effect of polypeptide hormones on stimulation of casein secretion by mouse mammary epithelial cells grown on floating collagen gels

1978 • 20 citations

The effects of egta and trypsin on the serum requirements for cell attachment to collagen

1979 • 20 citations

In Vitro Orientation of Fibroblasts and Myoblasts on Aligned Collagen Film

1981 • 16 citations

Blocking basement membrane collagen deposition inhibits the growth of 7,12-dimethylbenzanthracene-induced rat mammary tumors

1981 • 15 citations

Collagen and glycosaminoglycans in cell adhesion

1980 • 14 citations

Secretion of Casein in Cultures of Mouse Mammary Epithelial Cells on Floating Collagen Gels

1978 • 12 citations

Micro-Culture of Hela Cells and Human Embryo Liver on Poythene Disks

1963 • 10 citations

Attachment of human pancreatic tumor cell lines to collagen in vitro.

1981 • 9 citations

Clinical bladder cancer in sponge matrix tissue culture.Procedures for collection, cultivation, and assessment of viability

1978 • 9 citations

Adenovirus Infection of Human Embryo Liver Cells

1967 • 8 citations

Growth regulation of cells grown in suspension culture

1976 • 8 citations

Macrocrystalline Collagen (Avitene) Film as a Substrate for Outgrowth of Primary Rabbit Kidney Fibroblasts

1972 • 7 citations

Behavior of primary and serially transplanted estrogen-dependent renal carcinoma cells in monolayer and in collagen gel culture

1982 • 7 citations

Collagen cell attachment protein from rat hepatoma cells.

1981 • 6 citations

Chapter 13 Histophysiologic Gradient Culture of Stratified Epitbelium

1980 • 6 citations

The probable role of collagen when used as a growth surface for cell culture.

1972 • 5 citations

Growth Characteristics of a Hamster Cell Line on Collagen Gel

1974 • 1 citations